J Korean Ophthalmol Soc.
2003 Sep;44(9):2117-2121.
An Automatic System for the Delivery of Eye-Drops Using a Microinfusion Pump
- Affiliations
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- 1Department of Ophthalmology, Seoul National University, College of Medicine, Korea. wrwee@snu.ac.kr
- 2Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Korea.
- 3Department of Internal Medicine, College of Medicine, Konkuk University, Korea.
Abstract
- PURPOSE
To evaluate the efficacy of continuous drug delivery system using microinfusion pump by animal study METHODS: Schirmer test was performed after connecting the microinfusion pump at the superior fornix of rabbit eye. The pump was settled to instill artificial tears. We also evaluated the efficacy of continuous 0.1% fluorometholone infusion after alkali burn induced by 1N NaOH.
RESULTS
Average change in Schirmer tear test value was 12.0mm/5min. The recovery after alkali burn was improved in the eye of continuous infusion of steroid eye drops.
CONCLUSIONS
Microinfusion pump was thought to be useful as a continuous eye drops delivery system. It would be applicable to infuse artificial tears continuously in severe dry eye patients and to infuse antibiotic eye drops in infectous eye disease patients.
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