J Korean Child Neurol Soc.  2006 May;14(1):127-132.

Ischemic Encephalothy Found Accidentally in Children Diagnosed as Febrile Seizures

• Kim WS

Abstract

PURPOSE: Febrile seizures with ischemic encephalopathy were not mainly studied in children. Selected children with febrile seizures and ischemic encephalopathy were studied to evaluate the risk factors of developmental delay and epilepsy.
METHODS
Nine children with febrile seizures and hypoxic ischemic encephalopathy were retrospectively reviewed to evaluate the risk factors of epilepsy and developmental delay.
RESULTS
Nine patients with atypical febrile seizures have multiple ischemic lesions in the brain MRI. The average gestational period was 38 weeks. Four children have minor perinatal problems. Among them, 3 children were born as premature and one received ventilator care because of respiratory distress syndrome. The types of seizures were generalized seizures except two who showed partial type seizures. There were two cases of status epilepticus. During follow-ups, 3 children showed delayed development and academic difficulties. One patient were treated by antiepileptic drugs becuase of epilepsy during follow-up and one took valproic acid because of repeated atypical febrile convulsions.
CONCLUSION
Even though the number of the patients is guiet small, continous follow-ups of seizures and developmental status are needed in children with atypical febrile seizures with multifocal ischemic encephalopathy.

Keyword

Ischemic encephalopathy; Febrile seizures

MeSH Terms

Anticonvulsants
Brain
Brain Ischemia
Child*
Epilepsy
Follow-Up Studies
Humans
Hypoxia-Ischemia, Brain
Magnetic Resonance Imaging
Retrospective Studies
Risk Factors
Seizures
Seizures, Febrile*
Status Epilepticus
Valproic Acid
Ventilators, Mechanical
Anticonvulsants
Valproic Acid