- Hypoxia-inducible factor: role in cell survival in superoxide dismutase overexpressing mice after neonatal hypoxia-ischemia
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Jeon GW, Sheldon RA, Ferriero D
- KMID: 2469014
- Korean J Pediatr.
- 2019 Dec;62(12):444-449.
- doi: 10.3345/kjp.2019.00850
BACKGROUND: Sixty percent of infants with severe neonatal hypoxic-ischemic encephalopathy die, while most survivors have permanent disabilities. Treatment for neonatal hypoxic-ischemic encephalopathy is limited to therapeutic hypothermia, but it does... -
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- SYM 2081 Exerts Neuroprotective Effect Modulating Anti-Apoptosis in the Hypoxic-Ischemic Brain Injury of Neonatal Rats
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Park JK, Jang YY, Jeong JE, Lee EJ, Choi EJ, Chung HL, Kim WT
- KMID: 2460024
- Perinatology.
- 2019 Sep;30(3):117-125.
- doi: 10.14734/PN.2019.30.3.117
OBJECTIVE: SYM 2081 ((2S,4R)-4-methylglutamic acid), an agonist and functional antagonist of the kainite receptor, has shown a neuroprotective effect in neurodegenerative diseases in adults but little is known concerning perinatal... -
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- Paradoxical Motor and Cognitive Function Recovery in Response to Zolpidem in a Patient with Hypoxic-ischemic Brain Injury: A Case Report
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Hahm MH, Woo J
- KMID: 2457412
- Clin Psychopharmacol Neurosci.
- 2019 Aug;17(3):453-457.
- doi: 10.9758/cpn.2019.17.3.453
We report an extremely rare case of a patient with hypoxic-ischemic brain injury who recovered consciousness and motor and cognitive functions due to paradoxical response after zolpidem administration. A 32-year-old... -
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- Differential Effects of Pentoxifylline on Learning and Memory Impairment Induced by Hypoxic-ischemic Brain Injury in Rats
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Halis H, Bitiktaş , Baştuğ O, Tan B, Kavraal S, Güneş T, Süer C
- KMID: 2457402
- Clin Psychopharmacol Neurosci.
- 2019 Aug;17(3):388-399.
- doi: 10.9758/cpn.2019.17.3.388
OBJECTIVE: Hypoxic-ischemic (HI) brain injury in the human perinatal period often leads to significant long-term neurobehavioral dysfunction in the cognitive and sensory-motor domains. Using a neonatal HI injury model (unilateral... -
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- Neurodevelopmental Outcome of Severe Acidemic Term Infants
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Chang SH, Hong SH, Hwang IJ, Song ES, Choi YY
- KMID: 2453038
- Perinatology.
- 2019 Jun;30(2):54-59.
- doi: 10.14734/PN.2019.30.2.54
OBJECTIVE: This study aimed to evaluate the perinatal factors associated with neonatal mortality and neurologic morbidity in term infants with severe acidosis. METHODS: We retrospectively reviewed the data of term infants... -
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- A Functional Domain Based Approach in Neurocognitive Rehabilitation with Transcranial Direct Current Stimulation: A Case Report
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Sreeraj VS, Shivakumar V, Bose A, Abhiram PN, Agarwal SM, Chhabra H, Narayanaswamy JC, Venkatasubramanian G
- KMID: 2441641
- Clin Psychopharmacol Neurosci.
- 2019 Feb;17(1):125-129.
- doi: 10.9758/cpn.2019.17.1.125
Transcranial direct current stimulation (tDCS) is a novel brain stimulation technique which has kindled hope in alleviating motor, language as well as cognitive deficits in neuronal injury. Current case report... -
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- Predictors of Neurodevelopmental Outcomes in Newborns Undergoing Hypothermia Therapy
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Chun MK, Sung HJ, Park JH, Lim GY, Kim SY
- KMID: 2440696
- Neonatal Med.
- 2019 Feb;26(1):17-23.
- doi: 10.5385/nm.2019.26.1.17
PURPOSE: This study aimed to identify the early predictors of neurodevelopmental outcomes in infants undergoing therapeutic hypothermia for neonatal hypoxic ischemic encephalopathy. METHODS: The medical records of 24 neonates who underwent... -
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- Human Neural Stem Cells: Translational Research for Neonatal Hypoxic-Ischemic Brain Injury
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Shin JE, Han J, Lim JH, Eun HS, Park KI
- KMID: 2440695
- Neonatal Med.
- 2019 Feb;26(1):1-16.
- doi: 10.5385/nm.2019.26.1.1
Neonatal hypoxic-ischemic (HI) brain injury is a major cause of neonatal mortality and long-term neurodevelopmental disabilities. Although promising neuroprotective interventions have been studied, the current management of HI brain injury... -
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- Infant Percutaneous Endoscopic Gastrostomy: Risks or Benefits?
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Macchini F, Zanini A, Farris G, Morandi A, Brisighelli G, Gentilino , Fava G, Leva E
- KMID: 2414867
- Clin Endosc.
- 2018 May;51(3):260-265.
- doi: 10.5946/ce.2017.137
BACKGROUND/AIMS: To present a single center's experience with percutaneous endoscopic gastrostomy (PEG) tube placement in infants. METHODS: Clinical records of infants who underwent PEG tube placement between January 2010 and December... -
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- Therapeutic Hypothermia for Hypoxic-Ischemic Encephalopathy in Newborn Infants
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Sung IK
- KMID: 2396829
- Neonatal Med.
- 2017 Nov;24(4):145-156.
- doi: 10.5385/nm.2017.24.4.145
Neonatal hypoxic-ischemic encephalopathy (HIE) is an ongoing process, which may persist for weeks to years after an acute asphyxial insult, causing delayed programmed cell death. The typical clinical signs and... -
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- Utility of Susceptibility-Weighted Imaging in Comatose Patients after Cardiac Arrest: A Preliminary Study
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Hwang JT, Kim YH, Lee JH, Cho KW, Kang MJ, Lee DW, Song YG, Kim JM, Byun JH, Hwang SY, Lee JH
- KMID: 2394392
- J Korean Soc Emerg Med.
- 2017 Oct;28(5):441-448.
- doi: 10.0000/jksem.2017.28.5.441
PURPOSE: This study was conducted to examine the efficacies of susceptibility weighted images (SWI) for predicting the clinical prognosis of comatose patients following cardiac arrest. METHODS: Thirty-two patients who were resuscitated... -
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- Myoclonic status epilepticus in hypoxic ischemic encephalopathy which recurred after somatosensory evoked potential testing
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Kim S, Kim Y, Kim S, Lee SY
- KMID: 2387235
- Ann Clin Neurophysiol.
- 2017 Jul;19(2):136-140.
- doi: 10.14253/acn.2017.19.2.136
A 77-year-old male with amyotrophic lateral sclerosis had a hypoxic event. After resuscitation, generalized myoclonus appeared and resolved after two days. Five days after the hypoxic event, myoclonic seizures re-emerged... -
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- Contributing Factors on Pharmacokinetic Variability in Critically Ill Neonates
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An SH
- KMID: 2387585
- Korean J Clin Pharm.
- 2017 Jun;27(2):63-68.
- doi: 10.24304/kjcp.2017.27.2.63
Neonates have large inter-individual variability in pharmacokinetic parameters of many drugs due to developmental differences. The aim of this study was to investigate the factors affecting the pharmacokinetic parameters of... -
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- Neuroprotective effects of erythropoietin against hypoxic injury via modulation of the mitogen-activated protein kinase pathway and apoptosis
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Jeong JE, Park JH, Kim CS, Lee SL, Chung HL, Kim WT, Lee EJ
- KMID: 2383997
- Korean J Pediatr.
- 2017 Jun;60(6):181-188.
- doi: 10.3345/kjp.2017.60.6.181
PURPOSE: Hypoxic-ischemic encephalopathy is a significant cause of neonatal morbidity and mortality. Erythropoietin (EPO) is emerging as a therapeutic candidate for neuroprotection. Therefore, this study was designed to determine the... -
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- Stem Cell Therapy for Neonatal Disorders: Prospects and Challenges
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Chang YS, Ahn SY, Sung S, Park WS
- KMID: 2427113
- Yonsei Med J.
- 2017 Mar;58(2):266-271.
- doi: 10.3349/ymj.2017.58.2.266
Despite recent advances in neonatal medicine, neonatal disorders, such as bronchopulmonary dysplasia and intraventricular hemorrhage in preterm neonates and hypoxic ischemic encephalopathy in term neonates, remain major causes of mortality... -
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- Neurodevelopmental Outcomes According to Brain Injury Patterns in Neonates with Postasphyxial Hypoxic Ischemic Encephalopathy
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Jeong SY, Choi SY, Chang YP, Lee YS
- KMID: 2371413
- Neonatal Med.
- 2017 Feb;24(1):32-39.
- doi: 10.5385/nm.2017.24.1.32
PURPOSE: To investigate the relationship between brain injury patterns on magnetic resonance imaging (MRI) and neurodevelopmental outcomes in neonates with postasphyxial hypoxic ischemic encephalopathy (HIE). METHODS: Clinical characteristics and brain MRI... -
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- Human Umbilical Cord Blood CD34-Positive Cells as Predictors of the Incidence and Short-Term Outcome of Neonatal Hypoxic-Ischemic Encephalopathy: A Pilot Study
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Hassanein , Nasr Eldin MH, Amer HA, Abdelhamid AE, El Houssinie M, Ibrahim A
- KMID: 2364902
- J Clin Neurol.
- 2017 Jan;13(1):84-90.
- doi: 10.3988/jcn.2017.13.1.84
BACKGROUND AND PURPOSE: Neonatal hypoxic-ischemic encephalopathy (HIE) is one of the leading causes of neurological handicap in developing countries. Human umbilical cord blood (hUCB) CD34-positive (CD34âº) stem cells exhibit the... -
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- Brain Death in a Near-Term Infant: A Case Report
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Lee DJ, Choi HA, Lee YK, Ko SY, Shin SM
- KMID: 2367037
- Perinatology.
- 2016 Dec;27(4):251-254.
- doi: 10.14734/PN.2016.27.4.251
Brain death is defined as the complete and irreversible loss of cerebral and brainstem function while the heart continues to beat. Unlike cardiac death, brain death is associated with medical,... -
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- Cardiac arrest in a pregnant woman with pregnancy-induced hypertension: A case report
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Yoon HJ, Kim YD, Jee YS
- KMID: 2344930
- Anesth Pain Med.
- 2016 Jul;11(3):269-272.
- doi: 10.17085/apm.2016.11.3.269
A 39-year-old woman with an intrauterine pregnancy and small-for-gestational-age fetus was admitted at 34 + 1 weeks for management of pregnancy-induced hypertension. On the 13th day of admission, the patient... -
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- A study of the use of home mechanical ventilator and medical insurance
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Mun SW, Kim HY, Kim HY, Park HJ, Kim SY, Shin YB, Son SK
- KMID: 2165081
- Allergy Asthma Respir Dis.
- 2016 May;4(3):195-198.
- doi: 10.4168/aard.2016.4.3.195
PURPOSE: Use of a home mechanical ventilator can shorten the hospitalization duration of children with chronic respiratory failure requiring long-term use of a mechanical ventilator. In this study, the researchers... -
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