J Korean Soc Neonatol.  2012 Nov;19(4):269-274. 10.5385/jksn.2012.19.4.269.

Initiation of Therapeutic Hypothermia with a Cooling Fan for an Asphyxiated Newborn

• Lee SH
• Jang WJ
• Cho HJ
• Cho KH
• Shim SY
• Son DW

• KMID: 2188324
• DOI: http://doi.org/10.5385/jksn.2012.19.4.269

Abstract

Induced hypothermia for newborns with hypoxic-ischemic encephalopathy results in a significant decrease in mortality and neurodevelopmental disability. For optimal neuroprotection following perinatal hypoxia-ischemia (HI), therapy should begin within 6 hrs of the insult and continue for > or =72 hrs. We report on a baby with HI who underwent therapeutic hypothermia that was initiated with a cooling fan, as the whole-body cooling machine was in use for another patient. Although overcooling occurred, the method was successful. For effective and safe brain hypothermic therapy (BHT), a purpose-built cooling machine is recommended. The adherence to standard protocol is required for every BHT, as clearly defined by protocols similar to those used in published trials.

Keyword

Asphyxia neonatorum/therapy; Combined modality therapy; Electroencephalography; Guideline adherence; Heart rate; Humans; Hypothermia/therapy; Hypoxia-ischemia brain/therapy; Induced hypothermia; Infant newborn

MeSH Terms

Brain
Butylated Hydroxytoluene
Combined Modality Therapy
Electroencephalography
Guideline Adherence
Heart Rate
Humans
Hypothermia
Hypothermia, Induced
Hypoxia-Ischemia, Brain
Infant, Newborn
Butylated Hydroxytoluene