J Korean Bal Soc.  2003 Jun;2(1):129-132.

Neuro-Behcet's Disease Presenting with Foville Syndrome : A Case Report

• Chung WH
• Park SA
• Lee TK
• Sung KB

Abstract

A Foville syndrome is rare. A 46-year-old man with a 3-year history of Behcet's disease presented with a right facial palsy and a limitation in the rightward movements of the eyes. On neurologic examination, there was no movement of eyes in the right hemifield during all kinds of eye movements, including saccade, smooth pursuit, vestibulo-ocular reflex, and optokinetic nystagmus. However, all the eye movements were normal in the left hemifiled except for slowed saccades toward the right. Additional features were right infranuclear facial paresis and extensor plantar response on left side. Brain MRI revealed high signal intensity lesions in the right pons both in the dorsal tegmentum and in the basis. Neurological signs resolved gradually with steroid treatment. Different clinical features between abducens nucleus syndrome and paramedian pontine reticular formation syndrome are briefly discussed. To the authors' knowledge, this is the first case report of a Foville syndrome caused by neuro-Behcet's disease.

Keyword

Foville syndrome; Neuro-Behcet's disease; Horizontal gaze palsy; Abducens nucleus; Paramedian pontine reticular formation (PPRF)

MeSH Terms

Brain
Brain Stem Infarctions*
Eye Movements
Facial Paralysis
Humans
Magnetic Resonance Imaging
Middle Aged
Neurologic Examination
Nystagmus, Optokinetic
Pons
Pursuit, Smooth
Reflex, Babinski
Reflex, Vestibulo-Ocular
Reticular Formation
Saccades