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Selective impairment of the rapid eye movements in myotonic dystrophy

Kim SH, Park JS

The patients with myotonic dystrophy (MD) show ocular motor abnormalities including strabismus, vergence deficits, and inaccurate or slow saccades. Two theories have been proposed to explain the oculomotor deficits in...
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No Evidence of a Contribution of the Vestibular System to Frequent Falls in Progressive Supranuclear Palsy

Goldschagg N, Bremova-Ertl T, Bardins S, Dinca N, Feil K, Krafczyk S, Lorenzl S, Strupp M

BACKGROUND AND PURPOSE: Conflicting results about vestibular function in progressive supranuclear palsy (PSP) prompted a systematic examination of the semicircular canal function, otolith function, and postural stability. METHODS: Sixteen patients with...
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Two Cases of Myasthenia Gravis Showing Fatigibility Presenting with Decreased Gain of Smooth Pursuit

Chae JH, Shin HJ, Shin BS, Seo MW, Oh SY

Myasthenia gravis (MG) is an autoimmune disease caused by autoantibodies to the acetylcholine receptors of the neuromuscular junction characterized by weakness and abnormal fatigability of the muscles. Therefore, the diagnosis...
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Proposal on the Diagnostic Criteria of Definite Isolated Otolith Dysfunction

Park HG, Lee JH, Oh SH, Park MK, Suh MW

BACKGROUND AND OBJECTIVES: Dizzy patients with abnormal otolith function tests, despite a normal caloric response, are defined as having specific (isolated) otolith organ dysfunction. This study was performed to compare...
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Analysis of Age-Dependent Normative Values of Suppression Video-Head-Impulse Test in Healthy Korean Subjects

Jeong DY, Park YS, Cho SI

OBJECTIVES: Suppression head impulse paradigm (SHIMP) in video head impulse test is now newly used to test vestibular function. The aim of this study was to analyze normative values of...
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A Case of Patient with Acute Peripheral Vestibulopathy Involving Isolated Posterior Semicircular Canal

Im SK, Song MH, Gu JW, Shim DB

Down-beat nystagmus in peripheral vestibulopathy may rarely occur in selective involvement of inferior division. Diagnosis of isolated inferior vestibular neuritis is based on torsional down-beating spontaneous nystagmus, abnormal head-impulse test...
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The Value of Posterior Semicircular Canal Function in Predicting Hearing Recovery of Sudden Sensorineural Hearing Loss

Shin JW, Kim SW, Kim YW, Jang W, Kim BH, Lim YS, Park SW, Cho CG, Park JH

OBJECTIVES: Postulated etiologies for idiopathic sudden sensorineural hearing loss (SSNHL) include viral cochleitis, microvascular events. If SSNHL is caused by vascular compromise of common cochlear artery that supplies cochlea and...
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Comparison of Suppression Head Impulse and Conventional Head Impulse Test Protocols

Roh KJ, Kim JY, Son EJ

OBJECTIVES: The head impulse test paradigm (HIMP) assesses semicircular canal function by measuring compensatory saccades during head movements as an indication of an impaired vestibulo-ocular reflex (VOR). The recently introduced...
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Intratympanic Gentamicin Versus Labyrinthectomy: Inner Ear Sensitivity to Gentamicin and Impact on the Contralateral Labyrinth

Kontorinis G, Tailor H, Gaggini M, Crowther J

OBJECTIVES: To investigate the impact of labyrinthectomy and intratympanic (IT) gentamicin injections on the contralateral labyrinth, we also assessed the response of each individual semicircular canal to each IT gentamicin...
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Abnormal Eye Movements in Parkinsonism and Movement Disorders

Jung I, Kim JS

Abnormal eye movements are commonly observed in movement disorders. Ocular motility examination should include bedside evaluation and laboratory recording of ocular misalignment, involuntary eye movements, including nystagmus and saccadic intrusions/oscillations,...
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The Relationship between Saccades and Locomotion

Srivastava A, Ahmad OF, Pacia CP, Hallett M, Lungu C

Human locomotion involves a complex interplay among multiple brain regions and depends on constant feedback from the visual system. We summarize here the current understanding of the relationship among fixations,...
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Clinical Application and Update of Video Head Impulse Test

Lee JY, Park JS, Kim MB

Recently with the introduction of video head impulse test (vHIT), it can be easily performed quantitative and objective measurement of vestibulo-ocular reflex (VOR). vHIT has been used as a clinical...
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The Clinical Efficacy of Vestibular Function Tests in Patients with Acute Unilateral Vestibulopathy

Kang BH, Kim JI

OBJECTIVES: Aim of this study is to investigate the clinical efficacy of the vestibular function tests (VFTs) and the predictability of lesion side of vestibular asymmetry parameters in acute unilateral...
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Clinical Feasibility of Suppression Head Impulse Test in Vestibulopathy Patients

Kang YJ, Jun BC, Cho YS, Lim JH, Kim DY

BACKGROUND AND OBJECTIVES: The suppression head impulse (SHIMP) test has emerged as one of the new vestibular function tests. The SHIMP test is an analysis of anti-compensatory saccadic movements in...
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Association of Abnormal Eye Gaze Pattern with Magical Ideation during Reality Evaluation in Patients with Schizophrenia

Lee JS, Kim MW, Hong YJ, Kim JJ

OBJECTIVES: Magical ideation refers to belief in forms of causation that by conventional standards are invalid, and is considered to be one of prodromal psychotic symptoms in schizophrenia. This study...
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Roles of the Declive, Folium, and Tuber Cerebellar Vermian Lobules in Sportspeople

Park IS, Lee NJ, Rhyu IJ

The cerebellum plays vital roles in balance control and motor learning, including in saccadic adaptation and coordination. It consists of the vermis and two hemispheres and is anatomically separated into...
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Decoding Saccadic Directions Using Epidural ECoG in Non-Human Primates

Lee J, Choi H, Lee S, Cho BH, Ahn KH, Kim IY, Lee KM, Jang DP

A brain-computer interface (BCI) can be used to restore some communication as an alternative interface for patients suffering from locked-in syndrome. However, most BCI systems are based on SSVEP, P300,...
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Clinical significance of saccade test, smooth pursuit test, and optokinetic nystagmus test in nystagmography

Choi YS, Na HG, Song SY, Kim YD, Bae CH

BACKGROUND: Saccade test, smooth pursuit test, and optokinetic nystagmus test are clinically useful tests to accurately diagnose vertigo. However, there have only been a few studies regarding a correlation between...
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Causes of False Negative Bedside Head Impulse Test

Kim DY, Choi YG, Kyung TS, Hwang JH, Kim HJ, Lee SC, Kim KS

BACKGROUND AND OBJECTIVES: The bedside head impulse test (bHIT) in bare eyes often overlooks possible vestibular losses by missing the corrective saccade. This is why it is necessary to compare...
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Can pursuit eye movements reflect the efficacy of antiepileptic drugs?

Kim SE, Park KM

BACKGROUND: We evaluated whether eye movements could reflect the efficacy of antiepileptic drugs in patients with epilepsy. METHODS: Thirty patients with epilepsy of unknown cause as well as age- and sex-matched...
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