Yeungnam Univ J Med.  2013 Dec;30(2):95-100.

Epidemiology and Clinical Features of Respiratory Viruses in Pediatric Inpatients in a Single Medical Center in Daegu from 2010 to 2012

• Lee EK
• Lee YY
• Choi KH

Abstract

BACKGROUND
This study was performed to investigate the epidemiologic and clinical features of acute respiratory viral infection in hospitalized children.
METHODS
From 2010 to 2012, we tested nasopharyngeal swab specimen in 1,584 hospitalized children with multiple real-time polymerase chain reactions to identify 10 kinds of respiratory viruses (including influenza virus A, B (FluA, FluB), respiratory syncytial virus (RSV), human metapneumovirus (MPV), adenovirus (AdV), human coronavirus (CoronaV), human enterovirus (HEV), human bocavirus (HBoV), parainfluenza virus (PIV), and human rhinovirus (Rhinovirus)). We analyzed the positive rate, annual and seasonal variations, and clinical features (respiratory tract and non-respiratory tract) according to the retrospective review of medical records.
RESULTS
Respiratory viruses were detected from 678 (42.8%) of 1,584 patients. The most common detected virus was RSV (35.0%), and then AdV (19.0%), HEV (18.1%). The critical period of the respiratory viral infection was during the first 12 months of a child's life. PIV increased by 8.4%, 12.1%, and 21.1% annually. Bronchiolitis was most frequently caused by RSV, and croup was frequently caused by PIV. The most common cause of meningitis was HEV. Hepatitis-associated respiratory virus was developed 111 in 678 cases.
CONCLUSION
Although this study was confined to a single medical center for three years, we identified the epidemiology and clinical feature of respiratory viruses in Daegu from 2010 to 2012. Future surveillance will be necessary for annual and seasonal variations.

Keyword

Respiratory tract infections; Respiratory virus; Epidemiology

MeSH Terms

Adenoviridae
Bronchiolitis
Child
Child, Hospitalized
Coronavirus
Critical Period (Psychology)
Croup
Daegu*
Enterovirus
Epidemiology*
Human bocavirus
Humans
Inpatients*
Medical Records
Meningitis
Metapneumovirus
Orthomyxoviridae
Paramyxoviridae Infections
Polymerase Chain Reaction
Respiratory Syncytial Viruses
Respiratory Tract Infections
Retrospective Studies
Rhinovirus
Seasons
Viruses