- Carrier Frequency of Spinal Muscular Atrophy in a Large-scale Korean Population
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Park JE, Yun SA, Roh EY, Yoon JH, Shin S, Ki CS
- KMID: 2470330
- Ann Lab Med.
- 2020 Jul;40(4):326-330.
- doi: 10.3343/alm.2020.40.4.326
Spinal muscular atrophy (SMA) is an autosomal recessive disease characterized by progressive proximal muscle weakness and atrophy. Given the recent introduction of gene therapies, knowledge of the SMA carrier frequency... -
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- Comparison Between the SFTS-QS Kit and the PowerChek SFTSV Real-time PCR Kit for the Detection of Severe Fever With Thrombocytopenia Syndrome Virus
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Yoo IY, Kim JY, Yoon YK, Huh HJ, Lee NY
- KMID: 2470328
- Ann Lab Med.
- 2020 Jul;40(4):317-320.
- doi: 10.3343/alm.2020.40.4.317
The recent increase in severe fever with thrombocytopenia syndrome (SFTS) cases has led to the development of the SFTS-QS kit (MiCoBioMed, Seongnam, Korea) for detecting the SFTS virus (SFTSV, now... -
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- Role of IL-17A in Chronic Rhinosinusitis With Nasal Polyp
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Ryu G, Bae JS, Kim JH, Kim EH, Lyu L, Chung YJ, Mo JH
- KMID: 2471233
- Allergy Asthma Immunol Res.
- 2020 May;12(3):507-522.
- doi: 10.4168/aair.2020.12.3.507
PURPOSE: Th17-associated inflammation is increased in chronic rhinosinusitis with nasal polyp (CRSwNP), and is associated with disease severity and steroid resistance. Overexpressed interleukin (IL)-17A affects CRSwNP by tissue remodeling, eosinophilic... -
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- Evaluation of Xpert Carba-R Assay v.2 to Detect Carbapenemase Genes in Two Hospitals in Korea
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Byun JH, Kim YA, Kim M, Kim B, Choi JY, Park YS, Yong D
- KMID: 2466013
- Ann Lab Med.
- 2020 May;40(3):209-215.
- doi: 10.3343/alm.2020.40.3.209
BACKGROUND: As the spread of carbapenemase-producing Enterobacteriaceae poses a critical threat to public health, rapid detection of carbapenemase genes is urgently required for prompt initiation of appropriate antimicrobial therapy and... -
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- Recent Advances in the Diagnosis and Management of Pneumocystis Pneumonia
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Tasaka S
- KMID: 2471889
- Tuberc Respir Dis.
- 2020 Apr;83(2):132-140.
- doi: 10.4046/trd.2020.0015
In human immunodeficiency virus (HIV)-infected patients, Pneumocystis jirovecii pneumonia (PCP) is a wellk-nown opportunistic infection and its management has been established. However, PCP is an emerging threat to immunocompromised patients... -
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- Effect of saccharin on inflammation in 3T3-L1 adipocytes and the related mechanism
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Kim HL, Ha AW, Kim WK
- KMID: 2471878
- Nutr Res Pract.
- 2020 Apr;14(2):109-116.
- doi: 10.4162/nrp.2020.14.2.109
BACKGROUND/OBJECTIVES: Excessive intake of simple sugars induces obesity and increases the risk of inflammation. Thus, interest in alternative sweeteners as a sugar substitute is increasing. The purpose of this study... -
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- False-Negative Results of Real-Time Reverse-Transcriptase Polymerase Chain Reaction for Severe Acute Respiratory Syndrome Coronavirus 2: Role of Deep-Learning-Based CT Diagnosis and Insights from Two Cases
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Li D, Wang D, Dong J, Wang N, Huang H, Xu H, Xia C
- KMID: 2471817
- Korean J Radiol.
- 2020 Apr;21(4):505-508.
- doi: 10.3348/kjr.2020.0146
The epidemic of 2019 novel coronavirus, later named as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is still gradually spreading worldwide. The nucleic acid test or genetic sequencing serves as... -
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- Identification of Molecular Signatures in Mild Intrinsic Atopic Dermatitis by Bioinformatics Analysis
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Yin H, Wang S, Gu C
- KMID: 2471339
- Ann Dermatol.
- 2020 Apr;32(2):130-140.
- doi: 10.5021/ad.2020.32.2.130
BACKGROUND: Atopic dermatitis (AD) is recognized as a common inflammatory skin disease and frequently occurred in Asian and Black individuals. OBJECTIVE: Since the limitation of dataset associated with human severe AD,... -
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- Epigenetic Regulation of Filaggrin Gene Expression in Human Epidermal Keratinocytes
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Lee J, Jang A, Seo SJ, Myung SC
- KMID: 2471338
- Ann Dermatol.
- 2020 Apr;32(2):122-129.
- doi: 10.5021/ad.2020.32.2.122
BACKGROUND: Loss-of-function mutations in the filaggrin gene (FLG), which encodes an epidermal protein crucial for the formation of a functional skin barrier, have been identified as a major predisposing factor... -
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- Oral health condition according to distribution of periodontopathic bacterial complex
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Kim JH, Lee DI, Im SU, Jeon ES, Song KB, Choi YH
- KMID: 2471983
- J Korean Acad Oral Health.
- 2020 Mar;44(1):41-47.
- doi: 10.11149/jkaoh.2020.44.1.41
OBJECTIVES: The purpose of this study was to evaluate the association between the distribution of periodontopathic bacteria and oral conditions. METHODS: Stimulated saliva was collected from 162 adults aged 60 years... -
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- Molecular epidemiology and characterization of Streptococcus mutans strains in Korea
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Kim SY, Bae IK, Lee JH, Shin JH, Kim JB
- KMID: 2471982
- J Korean Acad Oral Health.
- 2020 Mar;44(1):34-40.
- doi: 10.11149/jkaoh.2020.44.1.34
OBJECTIVES: We investigated the characteristics of Streptococcus mutans in the national culture collection from Korea. Twenty-nine (dental plaque, n=27; endodontic infections, n=1; blood, n=1) isolates were included in this study. METHODS:... -
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- Role of Efflux Pump Gene adeIJK to Multidrug Resistance in Acinetobacter baumannii Clinical Isolates
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Choi JA, Kim CM, Jang SJ, Cho SS, Jang CH, Ko YJ, Kang SH, Park G
- KMID: 2471858
- Ann Clin Microbiol.
- 2020 Mar;23(1):45-54.
- doi: 10.5145/ACM.2020.23.1.45
BACKGROUND: The emergence of multidrug-resistant Acinetobacter baumannii as a nosocomial pathogen is one of the major public health problems. The aim of this study was to evaluate the role of... -
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- Frequency of Mycobacterium tuberculosis Among M. tuberculosis Complex Strains Isolated from Clinical Specimen
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Cho H, Kim JB, Uh Y
- KMID: 2471856
- Ann Clin Microbiol.
- 2020 Mar;23(1):21-31.
- doi: 10.5145/ACM.2020.23.1.21
BACKGROUND: Rapid and accurate detection of Mycobacterium tuberculosis (MTB) is of primary importance for infection control and selection of anti-tuberculosis drugs. However, most clinical laboratories report MTB complex (MTC) without... -
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- Evaluation of Multiplex Polymerase Chain Reaction Assay for the Simultaneous Detection of Sexually Transmitted Infections Using Swab Specimen
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Park SH, Hwang KA, Ahn JH, Nam JH
- KMID: 2471837
- J Bacteriol Virol.
- 2020 Mar;50(1):44-54.
- doi: 10.4167/jbv.2020.50.1.044
Sexually transmitted infections (STIs) are caused by the spread of pathogens via sexual activity and can cause serious complications if left untreated, regardless of their symptoms. Therefore, early diagnosis of... -
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- Age-specific Prevalence of Porcine Reproductive and Respiratory Syndrome Virus, Porcine Circovirus Type 2, and Mycoplasma hyopneumoniae in Korea Pig Farms
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Kang I, Ham H
- KMID: 2471833
- J Bacteriol Virol.
- 2020 Mar;50(1):9-16.
- doi: 10.4167/jbv.2020.50.1.009
Porcine respiratory disease complex (PRDC) continues to be a significant economic problem to the swine industry. Porcine circovirus type 2 (PCV2), porcine reproductive and respiratory syndrome virus (PRRSV), and Mycoplasma... -
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- Case Report of Nodular Fasciitis in the Conjunctiva
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Kim JH, Na KS, Park CH, Lee SJ, Oh TH, Kim HS
- KMID: 2471773
- J Korean Ophthalmol Soc.
- 2020 Mar;61(3):303-306.
- doi: 10.3341/jkos.2020.61.3.303
PURPOSE: We report a case of nodular fasciitis of the conjunctiva that has not been previously reported in the Republic of Korea. CASE SUMMARY: A 18-year-old female patient presented with a... -
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- Comparison of Clinical Characteristics between Patients with Cytomegalovirus Positive and Negative Hypertensive Uveitis
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Kim JH, Lee JY, Choi JA
- KMID: 2471766
- J Korean Ophthalmol Soc.
- 2020 Mar;61(3):258-266.
- doi: 10.3341/jkos.2020.61.3.258
PURPOSE: To compare the clinical characteristics of hypertensive uveitis patients, with and without cytomegalovirus (CMV) infection. METHODS: CMV polymerase chain reaction (PCR) was performed on the aqueous humor of 61 patients... -
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- Inhibition of melanogenesis by sodium 2-mercaptoethanesulfonate
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Kim JH, Oh CT, Kwon TR, Kim JH, Bak DH, Kim H, Park WS, Kim BJ
- KMID: 2471036
- Korean J Physiol Pharmacol.
- 2020 Mar;24(2):149-156.
- doi: 10.4196/kjpp.2020.24.2.149
Sodium 2-mercaptoethanesulfonate (mesna) is a protective agent that is widely used in medicine because of its antioxidant effects. Recently, reactive oxygen species (ROS) were shown to increase pigmentation. Thus, ROS... -
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- Evaluation of Neo-Osteogenesis in Eosinophilic Chronic Rhinosinusitis Using a Nasal Polyp Murine Model
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Khalmuratova R, Lee M, Park JW, Shin HW
- KMID: 2468464
- Allergy Asthma Immunol Res.
- 2020 Mar;12(2):306-321.
- doi: 10.4168/aair.2020.12.2.306
PURPOSE: Osteitis refers to the development of new bone formation and remodeling of bone in chronic rhinosinusitis (CRS) patients; it is typically associated with eosinophilia, nasal polyps (NPs), and recalcitrant... -
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- Evidence for the Presence of Long-Lived Plasma Cells in Nasal Polyps
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Zhang YN, Song J, Zhai GT, Wang H, Luo RZ, Li JX, Liao B, Ma J, Wang H, Lu X, Liu DB, Liu Z
- KMID: 2468462
- Allergy Asthma Immunol Res.
- 2020 Mar;12(2):274-291.
- doi: 10.4168/aair.2020.12.2.274
PURPOSE: Plasma cells and immunoglobulins (Igs) play a pivotal role in the induction and maintenance of chronic inflammation in nasal polyps. During secondary immune responses, plasma cell survival and Ig... -
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