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Bacterial and Viral Identification Rate in Acute Exacerbation of Chronic Obstructive Pulmonary Disease in Korea

Choi J, Oh JY, Lee YS, Hur GY, Lee SY, Shim JJ, Kang KH, Min KH

PURPOSE: The most common cause of acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is respiratory infection. Most studies of bacterial or viral cause in AECOPD have been conducted in...
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Clinical and laboratory profiles of hospitalized children with acute respiratory virus infection

Choi E, Ha KS, Song DJ, Lee JH, Lee KC

PURPOSE: Despite the availability of molecular methods, identification of the causative virus in children with acute respiratory infections (ARIs) has proven difficult as the same viruses are often detected in...
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Distribution and Characterization of Airborne Respiratory Pathogens in Public Facilities

Hwang SJ, Yun HC, Ku PT, Sim JH, Cha YW, Lee MO

Respiratory infections, which are caused by airborne pathogens, are the most common disease of all ages worldwide. This study was conducted to characterize the airborne respiratory pathogens in the public...
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Bronchiolitis severity according to the infected viruses

Lee SJ, Park SK, Kim JH, Cho SM

PURPOSE: The aim of this study was to evaluate the severity of disease in children with acute bronchiolitis according to the type of infected virus. METHODS: From November 2007 to May...
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Study on Causes of Respiratory Disease to the Middle East Respiratory Syndrome-negative Subjects

Hwang SJ, Park DJ, Koo HS, Yun HC, Gu PT, Lee MO, Jin SH

Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe cases of human respiratory disease. The current outbreak of infection with this virus in South Korea, which began on May 20, 2015,...
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The epidemiology and clinical manifestation of human metapneumovirus infection in children during 2011–2014

Jang MS, Shin M

PURPOSE: This study was performed to investigate the epidemiologic and clinical features of human metapneumovirus (hMPV). METHODS: We performed real-time reverse transcription polymerase chain reaction with nasopharyngeal samples from 2,403 children...
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Comparison of the Luminex xTAG Respiratory Viral Panel Fast v2 Assay With Anyplex II RV16 Detection Kit and AdvanSure RV Real-Time RT-PCR Assay for the Detection of Respiratory Viruses

Ko DH, Kim HS, Hyun J, Kim HS, Kim JS, Park KU, Song W

BACKGROUND: The accurate and rapid identification of the causative viruses is important for the timely diagnosis and management of respiratory infections. Multiplex molecular diagnostic techniques have been widely adopted to...
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A Retrospective Study Investigating Risks of Acute Respiratory Distress Syndrome and Mortality Following Human Metapneumovirus Infection in Hospitalized Adults

Hwang H, Kim Y, Park JW, Jeong SH, Kyung SY

BACKGROUND: Human metapneumovirus (hMPV) is a relatively recently identified respiratory virus that induces respiratory symptoms similar to those of respiratory syncytial virus infection in children. The characteristics of hMPV-infected adults...
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Comparison of Luminex NxTAG Respiratory Pathogen Panel and xTAG Respiratory Viral Panel FAST Version 2 for the Detection of Respiratory Viruses

Lee CK, Lee HK, Ng CW, Chiu L, Tang JW, Loh TP, Koay ES

Owing to advancements in molecular diagnostics, recent years have seen an increasing number of laboratories adopting respiratory viral panels to detect respiratory pathogens. In December 2015, the NxTAG respiratory pathogen...
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Prevalence of Respiratory Viral Infections in Korean Adult Asthmatics With Acute Exacerbations: Comparison With Those With Stable State

Seo KH, Bae DJ, Kim JN, Lee HS, Kim YH, Park JS, Kim MS, Chang HS, Son JH, Baek DG, Lee JS, Park CS

PURPOSE: Viral infections are involved in ~50% of exacerbations among Caucasian adult asthmatics. However, there have been few reports on the causative virus of exacerbations in Korean adult asthmatics. Thus,...
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Elucidation of Bacterial Pneumonia-Causing Pathogens in Patients with Respiratory Viral Infection

Jung HS, Kang BJ, Ra SW, Seo KW, Jegal Y, Jun JB, Jung J, Jeong J, Jeon HJ, Ahn JS, Lee T, Ahn JJ

BACKGROUND: Bacterial pneumonia occurring after respiratory viral infection is common. However, the predominant bacterial species causing pneumonia secondary to respiratory viral infections other than influenza remain unknown. The purpose of...
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Comparison of nasal cytokine profiles of human metapneumovirus and respiratory syncytial virus

Park JS, Kim YH, Kwon E, Callaway Z, Fujisawa T, Kim CK

BACKGROUND: Human metapneumovirus (hMPV) and respiratory syncytial virus (RSV) share some epidemiological and clinical characteristics; however, few studies have examined the mechanisms by which these viruses induce airway inflammation. OBJECTIVE: This...
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Acute Myopericarditis caused by Human Metapneumovirus

Choi MJ, Song JY, Yang TU, Jeon JH, Noh JY, Hong KW, Cheong HJ, Kim WJ

Human metapneumovirus is known to be similar to respiratory syncytial virus. Because of an incomplete protective immune response to new genotypes, re-infection occurs frequently, especially in the elderly. However, the...
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Life-threatening human metapneumovirus pneumonia requiring extracorporeal membrane oxygenation in a 26-month-old child

Choi SH, Yoon SH, Sol IS, Kim MJ, Kim YH, Shin HJ, Kim KW, Sohn MH, Kim KE

We present the first case report of a child with human metapneumovirus (hMPV) pneumonia who survived by extracorporeal membrane oxygenation (ECMO) in Korea. A 26-month-old boy with a previous history...
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Clinical characteristics of respiratory viral infection in children during spring/summer: focus on human bocavirus

Kwak KJ, Kim YH, Choi HJ

PURPOSE: We evaluated the clinical characteristics of respiratory viruses that were frequently found in children during spring/summer, namely, human bocavirus (hBoV), human metapneumovirus (hMPV), parainfluenza virus (PIV), and human rhinovirus...
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Detection of Respiratory Viruses and Atypical Bacterial Pathogens in Infants with Acute Respiratory Infections Using Multiplex PCR

Yoo SJ, Han JU, Shin BM

Multiplex PCR of nasopharyngeal aspirates detected viruses and atypical bacteria in 75.3% (219/291) of infants with acute respiratory infections from July 2010 to June 2013. Frequent viruses were human rhinovirus...
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Etiology and Clinical Outcomes of Acute Respiratory Virus Infection in Hospitalized Adults

Seo YB, Song JY, Choi MJ, Kim IS, Yang TU, Hong KW, Cheong HJ, Kim WJ

BACKGROUND: Etiologies and clinical profiles of acute respiratory viral infections need to be clarified to improve preventive and therapeutic strategies. MATERIALS AND METHODS: A retrospective observational study at a single, university-affiliated...
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Risk Factors Associated with Respiratory Virus Detection in Infants Younger than 90 Days of Age

Eem YJ, Bae EY, Lee JH, Jeong DC

  • KMID: 1705183
  • Korean J Pediatr Infect Dis.
  • 2014 Apr;21(1):22-28.
PURPOSE: This study aimed at determining the detection rate of respiratory viruses and at investigating the risk factors associated with respiratory virus detection in young infants. METHODS: From September 2011 to...
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Association between Respiratory Virus Infection and Pneumococcal Colonization in Children

Lee HS, Choe YJ, Cho EY, Lee H, Choi EH, Lee HJ

PURPOSE: This study aimed to investigate the association between respiratory virus infection and pneumococcal colonization in children. METHODS: From May 2009 to June 2010, nasopharyngeal (NP) aspirates were obtained from patients...
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Prevalence of respiratory viral infection in children hospitalized for acute lower respiratory tract diseases, and association of rhinovirus and influenza virus with asthma exacerbations

Kwon JM, Shim JW, Kim DS, Jung HL, Park MS, Shim JY

PURPOSE: In this study, we aimed to investigate the prevalence of year-round respiratory viral infection in children with lower respiratory tract infection (LRTI) and the relationship between respiratory viral infection...
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