Allergy Asthma Respir Dis.  2015 Nov;3(6):456-460. 10.4168/aard.2015.3.6.456.

Life-threatening human metapneumovirus pneumonia requiring extracorporeal membrane oxygenation in a 26-month-old child

  • 1Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
  • 2Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.
  • 3Division of Cardiovascular Surgery, Congenital Heart Disease Center, Severance Cardiovascular Hospital, Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, Seoul, Korea.


We present the first case report of a child with human metapneumovirus (hMPV) pneumonia who survived by extracorporeal membrane oxygenation (ECMO) in Korea. A 26-month-old boy with a previous history of Lennox-Gastaut syndrome and delayed development suffered from respiratory failure after 4 days of fever, cough, and sputum. The boy underwent intubation and required ECMO application due to failure of conventional mechanical ventilation. He was on the ECMO support for 7 days. To our knowledge, this is the shortest period reported for ECMO application among successfully treated patients with hMPV infection accompanied by acute respiratory distress syndrome. This case highlights 2 clinical implications: the potentially fatal causative role of hMPV in respiratory failure in a pediatric population and the timely utilization of ECMO.


Human metapneumovirus; Child; Acute respiratory distress syndrome; Extracorporeal membrane oxygenations
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