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The incidence and risk factors of extrapulmonary manifestations in Mycoplasma pneumoniae pneumonia

Park YK, Park YN, Moon JE, Kim HB, Shin M, Lee E, Kim CH, Lee JS, Lee YJ, Kim BS, Kim HY, Jung S, Kim Y, Kim S, Park C, Seo JH, Shim JY, Sol IS, Sung M, Song DJ, Ahn YM, Oh HL, Yu J, Lee KS, Jang GC, Jang YY, Chung HL, Chung EH, Choi SM, Choi YJ, Han MY, Kim JT, Kim CK, Yang HJ

Purpose: Mycoplasma pneumoniae pneumonia (MP) is a major cause of community-acquired pneumonia (CAP) in children and is associated with extrapulmonary manifestations (EPM). The incidence and risk factors for EPM in...
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Multisystem Inflammatory Syndrome in Children Related to COVID-19: the First Case in Korea

Kim Hn, Shim JY, Ko JH, Yang A, Shim JW, Kim DS, Jung HL, Kwak JH, Sol IS

Since mid-April 2020, cases of multisystem inflammatory syndrome in children (MIS-C) associated with coronavirus disease 2019 that mimics Kawasaki disease (KD) have been reported in Europe and North America. However,...
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Trends of Sensitization to Inhalant Allergens in Korean Children Over the Last 10 Years

Kim YJ, Lee MY, Yang AR, Sol IS, Kwak JH, Jung HL, Shim JW, Kim DS, Shim JY

Purpose: Climate and lifestyle changes increase an individual’s susceptibility to various allergens and also the incidence of allergic diseases. We aimed to examine the changes in sensitization rate for aeroallergens...
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Organizing pneumonia as the initial presentation of systemic lupus erythematosus in a Korean adolescent

Kang SY, Kim SY, Choi SH, Sol IS, Kim YH, Shim HS, Lee MJ, Kim KW, Sohn MH

Organizing pneumonia is characterized histologically by the formation of granulation-tissue plugs within the lumens of small airways. It was reported in association with various disorders including infection, drug reactions and...
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Pediatric Home Mechanical Ventilation in Korea: the Present Situation and Future Strategy

Park M, Jang H, Sol IS, Kim SY, Kim YS, Kim YH, Sohn MH, Kim KW

BACKGROUND: The number of children using home mechanical ventilation (HMV) has increased markedly in Europe and North America, but little is known about the situation in Korea. We described the...
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Activated Leukocyte Cell Adhesion Molecule Modulates Th2 Immune Response in Atopic Dermatitis

Oh MS, Hong JY, Kim MN, Kwak EJ, Kim SY, Kim EG, Lee KE, Kim YS, Jee HM, Kim SH, Sol IS, Park CO, Kim KW, Sohn MH

PURPOSE: Activated leukocyte cell adhesion molecule (ALCAM), a member of the immunoglobulin superfamily, is highly expressed on dendritic cells. ALCAM and its receptor CD6 are co-stimulatory molecules in the immunological...
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Reduction Rate of Specific IgE Level as a Predictor of Persistent Egg Allergy in Children

Kim JD, Kim SY, Kwak EJ, Sol IS, Kim MJ, Kim YH, Kim KW, Sohn MH

PURPOSE: Egg is the most common food allergen in infants. However, the natural course of egg allergy has not been fully elucidated. This study aimed to describe clinical characteristics and...
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Usefulness of bronchodilator response as an index of asthma control in children

Kim JD, Kim SY, Kim YH, Kim KW, Sohn MH, Sol IS

PURPOSE: Assessing asthma control is important for proper management, and various indices for objective assessment of asthma control, such as fractional exhaled nitric oxide (FeNO) and asthma control test (ACT)...
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Seasonal patterns and etiologies of croup in children during the period 2010–2015: A multicenter retrospective study

Lee YJ, Kim HB, Kim BS, Kim CK, Kim CH, Kim HY, Kim S, Kim Y, Park C, Seo JH, Sol IS, Sung M, Song MS, Song DJ, Ahn YM, Oh HL, Yu J, Lee KS, Lee E, Lee JS, Jang GC, Jang YY, Chung EH, Chung HL, Choi SM, Choi YJ, Han MY, Yang HJ, Shim JY, Kim JT, The Pneumonia & Respiratory Disease Study Group of Korean Academy of Pediatric Allergy and Respiratory Disease

PURPOSE: Croup is known to have epidemics in seasonal and biennial trends, and to be strongly associated with epidemics of parainfluenza virus. However, seasonal and annual epidemics of croup have...
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Predicting the Outcome of Critically Ill Children and Adolescents with Electroencephalography

Lee S, Ko A, Sol IS, Kim KW, Kang HC, Lee JS, Kim HD, Kim SH

PURPOSE: Electroencephalography (EEG) is an effective test in predicting severe cortical dysfunction associated with poor outcomes in adult patients, but its value in pediatric patients remains incomplete. Here, we assessed...
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Prescription Patterns and Burden of Pediatric Asthma in Korea

Sol IS, Kim YH, Kim SY, Choi SH, Kim JD, Kim BO, Moon JE, Kim KW, Sohn MH

PURPOSE: This study aimed to estimate the prevalence, prescription pattern and burden of pediatric asthma in Korea by analyzing the National Health Insurance (NHI) claims data. METHODS: We retrospectively analyzed the...
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Clinical application of the Pediatric Acute Lung Injury Consensus Conference definition of acute respiratory distress syndrome

Kim BR, Kim SY, Sol IS, Kim YH, Kim KW, Sohn MH, Kim KE

PURPOSE: Despite improved quality of intensive care, acute respiratory distress syndrome (ARDS) significantly contributes to mortality in critically ill children. As pre-existing definitions of ARDS were adult-oriented standards, the Pediatric...
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Oxygenation Index in the First 24 Hours after the Diagnosis of Acute Respiratory Distress Syndrome as a Surrogate Metric for Risk Stratification in Children

Kim SY, Kim B, Choi SH, Kim JD, Sol IS, Kim MJ, Kim YH, Kim KW, Sohn MH, Kim KE

BACKGROUND: The diagnosis of pediatric acute respiratory distress syndrome (PARDS) is a pragmatic decision based on the degree of hypoxia at the time of onset. We aimed to determine whether...
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Validation of Pediatric Index of Mortality 3 for Predicting Mortality among Patients Admitted to a Pediatric Intensive Care Unit

Jung JH, Sol IS, Kim MJ, Kim YH, Kim KW, Sohn MH

BACKGROUND: The objective of this study was to evaluate the usefulness of the newest version of the pediatric index of mortality (PIM) 3 for predicting mortality and validating PIM 3...
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Etiology and clinical feature of oral allergy syndrome in children

Park YA, Jeong KU, Kim YH, Sol IS, Kim KW, Sohn MH, Lee SY, Kim KE

PURPOSE: Oral allergy syndrome (OAS) is a unique allergic reaction to fresh fruits or vegetables, which is caused by cross-reactivity between foods and pollens. This study was conducted to investigate...
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Life-threatening Hemorrhage Caused by Mandibular Arteriovenous Malformation: A Case Report

Kim DW, Sol IS, Kim MJ, Kim SY, Kim JD, Choi BS, Kim YH, Kim DJ, Kim BM, Jung SY, Nam W, Kim KW, Sohn MH, Kim KE

Arteriovenous malformation (AVM) of the mandible is a rare vascular condition that can manifest as a wide range of symptoms and, on rare occasions, cause fatal hemorrhage. The symptoms of...
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Serum Albumin as a Biomarker of Poor Prognosis in the Pediatric Patients in Intensive Care Unit

Kim YS, Sol IS, Kim MJ, Kim SY, Kim JD, Kim YH, Kim KW, Sohn MH, Kim KE

BACKGROUND: Serum albumin as an indicator of the disease severity and mortality is suggested in adult patients, but its role in pediatric patients has not been established. The objectives of...
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Clinical implication of exhaled breath temperature measurement in pediatric asthma

Kim SY, Kim JY, Han YK, Kim JD, Sol IS, Park YA, Kim YH, Kim KW, Sohn MH, Kim KE

PURPOSE: Exhaled breath temperature (EBT) has been suggested as a noninvasive marker of airway inflammation in asthma. The aim of this study was to determine its clinical implication in children...
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Usefulness of the RESP, PRESERVE, and ECMOnet scores for extracorporeal membrane oxygenation in children with acute respiratory distress syndrome

Ahn WK, Han JH, Kim YH, Sol IS, Yoon SH, Kim MJ, Kim KW, Sohn MH, Kim KE

PURPOSE: With increasing use of extracorporeal membrane oxygenation (ECMO) for acute respiratory distress syndrome (ARDS) in children, development of standardized strategies for survival prediction has become crucial; however, this has...
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Delta Neutrophil Index as a Prognostic Marker in the Pediatric Intensive Care Unit

Sol IS, Park HB, Kim MJ, Yoon SH, Kim YH, Kim KW, Sohn MH, Kim KE

BACKGROUND: The delta neutrophil index (DNI) is a useful marker for diagnosing and predicting the prognosis of sepsis. The purpose of this study was to investigate the usefulness of DNI...
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