Korean J Med.  2003 Dec;65(6):702-706.

A case of Salmonella enterica serovar Typhi endocarditis with multiple splenic infarctions

• Park KM
• Kim NJ
• Oh DR
• Park JT
• Kim YS
• Woo JH
• Ryu J

Abstract

Infective endocarditis is a very rare cardiac manifestation of salmonella infection, and splenic infarction is a rare noncardiac complication. We describe a case of Salmonella enterica serovar Typhi bacteremia which was complicated by infective endocarditis with multiple splenic infarctions in a previously healthy 47-year-old female. She didn't have any history of foreign travel. The isolate of Salmonella enterica serovar Typhi was susceptible to cephalosporins, aminoglycosides, quinolones but resistant to ampicillin. After 3 weeks of intravenous and oral therapy with ciprofloxacin, follow up transthoracic and transesophageal echocardiography showed no vegetation. In addition, follow up abdominal CT showed decreased size of splenic infarctions. The patient was treated with 2 weeks of intravenous and 4 weeks of oral ciprofloxacin, and was cured without sequelae or relapse for 6 months follow-up.

Keyword

Salmonella enterica serovar Typhi; Endocarditis; Splenic infarction

MeSH Terms

Aminoglycosides
Ampicillin
Bacteremia
Cephalosporins
Ciprofloxacin
Echocardiography, Transesophageal
Endocarditis
Female
Follow-Up Studies
Humans
Middle Aged
Quinolones
Recurrence
Salmonella enterica*
Salmonella Infections
Salmonella typhi*
Salmonella*
Splenic Infarction*
Tomography, X-Ray Computed
Aminoglycosides
Ampicillin
Cephalosporins
Ciprofloxacin
Quinolones