Korean J Pediatr.  2009 Feb;52(2):256-260. 10.3345/kjp.2009.52.2.256.

A case of idiopathic pulmonary hemosiderosis with seasonal recurrence

• Kwak GY
• Lee NY
• Lee MH
• Lee SY
• Chung SY
• Kang JH
• Jeong DC

• KMID: 2281685
• DOI: http://doi.org/10.3345/kjp.2009.52.2.256

Abstract

Idiopathic pulmonary hemosiderosis (IPH) is a rare disease affecting mostly children. This disorder is characterized by recurrent episodes of hemoptysis, bilateral diffuse pulmonary infiltrates, and iron-deficiency anemia. An acute fulminant alveolar hemorrhage can be fatal due to respiratory failure, while chronic hemorrhage leads to hemosiderin-laden macrophages and pulmonary fibrosis. Genetic, autoimmune, allergic, environmental, and metabolic mechanisms of pathogenesis have been suggested, but the etiology of IPH remains unknown. We report on a 9-year-old girl with idiopathic pulmonary hemosiderosis who showed seasonal recurrences without cause.

Keyword

Idiopathic pulmonary hemosiderosis; Seasonal recurrence

MeSH Terms

Anemia, Iron-Deficiency
Child
Hemoptysis
Hemorrhage
Hemosiderosis
Humans
Lung Diseases
Macrophages
Pulmonary Fibrosis
Rare Diseases
Recurrence
Respiratory Insufficiency
Seasons
Hemosiderosis
Lung Diseases