- Anti-Inflammatory Effect for Atherosclerosis Progression by Sodium-Glucose Cotransporter 2 (SGLT-2) Inhibitor in a Normoglycemic Rabbit Model
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Lee SG, Lee SJ, Lee JJ, Kim JS, Lee OH, Kim CK, Kim D, Lee YH, Oh J, Park S, Jeon OH, Hong SJ, Ahn CM, Kim BK, Ko YG, Choi D, Hong MK, Jang Y
- KMID: 2471785
- Korean Circ J.
- 2020 May;50(5):443-457.
- doi: 10.4070/kcj.2019.0296
BACKGROUND AND OBJECTIVES: We sought to investigate an anti-atherosclerotic and anti-inflammatory effect of sodium-glucose cotransporter-2 (SGLT-2) inhibitors in normoglycemic atherosclerotic rabbit model. METHODS: Male New Zealand white rabbits (n=26) were fed... -
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- Role of IL-17A in Chronic Rhinosinusitis With Nasal Polyp
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Ryu G, Bae JS, Kim JH, Kim EH, Lyu L, Chung YJ, Mo JH
- KMID: 2471233
- Allergy Asthma Immunol Res.
- 2020 May;12(3):507-522.
- doi: 10.4168/aair.2020.12.3.507
PURPOSE: Th17-associated inflammation is increased in chronic rhinosinusitis with nasal polyp (CRSwNP), and is associated with disease severity and steroid resistance. Overexpressed interleukin (IL)-17A affects CRSwNP by tissue remodeling, eosinophilic... -
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- Potential Biomarkers to Improve the Prediction of Osteoporotic Fractures
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Kim BJ, Lee SH, Koh JM
- KMID: 2471720
- Endocrinol Metab.
- 2020 Mar;35(1):55-63.
- doi: 10.3803/EnM.2020.35.1.55
Osteoporotic fracture (OF) is associated with high disability and morbidity rates. The burden of OF may be reduced by early identification of subjects who are vulnerable to fracture. Although the... -
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- Select Macrophage Noncoding RNAs of Interest in Cardiovascular Disease
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Enchill Z, Lantz C, Thorp EB
- KMID: 2470807
- J Lipid Atheroscler.
- 2020 Jan;9(1):153-161.
- doi: 10.12997/jla.2020.9.1.153
Cardiovascular disease remains a leading cause of morbidity and mortality worldwide. Aspects of disease severity that are associated with heightened inflammation, such as during atherosclerosis or after myocardial infarction, are... -
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- Focal Xanthogranulomatous Pyelonephritis Associated with Xanthogranulomatous Cholecystitis: A Case Report
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Cho SM, Kim HK, Lee HK, Lee B, Kim KH, Lee KE, Shim JC, Hwang DH, Lee GJ
- KMID: 2469192
- J Korean Soc Radiol.
- 2020 Jan;81(1):190-196.
- doi: 10.3348/jksr.2020.81.1.190
Xanthogranulomatous inflammation is a rare inflammatory reaction, characterized by lipid-laden macrophages, known as xanthomas, in histopathologic examination. Aggressive xanthogranulomatous inflammation often manifests as local infiltration but does not affect distant... -
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- Differential Activation of Macrophages Based on Their Environment in Advanced Age
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Lee DY, Lim JS, Cho KA
- KMID: 2468141
- Chonnam Med J.
- 2020 Jan;56(1):12-19.
- doi: 10.4068/cmj.2020.56.1.12
The macrophage displays functional and phenotypic diversity, which appears, in no small part, to stem from the ability of macrophages to adapt functionally to changes in their tissue microenvironment. Here,... -
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- Scavenger Receptor Class A to E Involved in Various Cancers
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Ryu S, Howland A, Song B, Youn C, Song PI
- KMID: 2468139
- Chonnam Med J.
- 2020 Jan;56(1):1-5.
- doi: 10.4068/cmj.2020.56.1.1
Scavenger receptors typically bind to multiple ligands on a cell surface, including endogenous and modified host-derived molecules and microbial pathogens. They promote the elimination of degraded or harmful substances such... -
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- Polymorphism in Macrophage Migration Inhibitory Factor -173GC in Pediatric Patients with Autoimmune Hepatitis
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Alsayed MA, Elbeah SM, El-Desoky , Elziny SM, Megahed A
- KMID: 2467894
- Pediatr Gastroenterol Hepatol Nutr.
- 2020 Jan;23(1):63-71.
- doi: 10.5223/pghn.2020.23.1.63
PURPOSE: Autoimmune hepatitis (AIH) is a chronic disease that may lead to cirrhosis. The immunopathogenesis of AIH is not fully understood and it mainly involves T-cell mediated mechanism. Macrophage migration... -
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- Aspergillus fumigatus infection in an ostrich with an enlarged neck due to respiratory problems
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- KMID: 2470124
- Korean J Vet Res.
- 2019 Dec;59(4):227-230.
- doi: 10.14405/kjvr.2019.59.4.227
This study describes a sudden death in an ostrich (Struthio camelus) with a big neck. Grossly, the air sacs were thickened. Yellow to white, round or coalescent material was scattered... -
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- Macrophages in xenotransplantation
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Kim JY
- KMID: 2468157
- Korean J Transplant.
- 2019 Dec;33(4):74-82.
- doi: 10.4285/jkstn.2019.33.4.74
Xenotransplantation refers to organ transplantation across species. Immune rejection of xenografts is stronger and faster than that of allografts because of significant molecular differences between species. Recent studies have revealed... -
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- Anti-arthritic Effects of Oplopanax elatus in a Rat Model of Rheumatoid Arthritis (Adjuvant-induced Arthritis)
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Kwon KS, Lim H, Kwon YS, Choi HR, Kim MJ, Yoo JH, Yoo NH, Kim HP
- KMID: 2468063
- Nat Prod Sci.
- 2019 Dec;25(4):304-310.
- doi: 10.20307/nps.2019.25.4.304
The stems of Oplopanax elatus (OE) have long been used to treat inflammatory disorders in herbal medicine, and in the previous investigation, OE was found to possess anti-inflammatory activity in... -
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- PD-1: A Negative Regulator of Phagocytosis by Tumour-Associated Macrophages in Colon Cancer
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Islam Tultul MS, Koh YS
- KMID: 2468029
- J Bacteriol Virol.
- 2019 Dec;49(4):230-236.
- doi: 10.4167/jbv.2019.49.4.230
Programmed cell death protein 1 (PD-1) is an immuno-inhibitory cell surface receptor protein of the myeloid, and lymphoid cell. PD-L1 is the ligand of PD-1, which is abundant in different... -
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- Aralia cordata Extract Activates NF-κB and MAPK Signaling Pathways and Induces Pro-inflammatory Changes in RAW264.7 Macrophages
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Seo DW, Cho YI, Yi YJ, Lee SM
- KMID: 2468022
- J Bacteriol Virol.
- 2019 Dec;49(4):153-161.
- doi: 10.4167/jbv.2019.49.4.153
Macrophages play essential roles in innate immune responses by producing various immune mediators. Therefore, modulating macrophage function is an attractive strategy to treat immune disorders. Aralia cordata var. continentalis (AC),... -
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- An Important Role of Macrophages for Wound Margin Regeneration in a Murine Flap Model
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Won HR, Seo C, Lee HY, Roh J, Kim CH, Jang JY, Shin YS
- KMID: 2467058
- Tissue Eng Regen Med.
- 2019 Dec;16(6):667-674.
- doi: 10.1007/s13770-019-00214-x
BACKGROUND: Macrophages have been known to have diverse roles either after tissue damage or during the wound healing process; however, their roles in flap wound healing are poorly understood. In... -
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- Splenocyte-mediated immune enhancing activity of Sargassum horneri extracts
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Kim DS, Sung NY, Han IJ, Lee BS, Park SY, Nho EY, Eom J, Kim G, Kim KA
- KMID: 2466666
- J Nutr Health.
- 2019 Dec;52(6):515-528.
- doi: 10.4163/jnh.2019.52.6.515
PURPOSE: This study examined the immunological activity and optimized the mixture conditions of Sargassum horneri (S. horneri) extracts in vitro and in vivo models. METHODS: S. horneri was extracted using three... -
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- Zika Virus Impairs Host NLRP3-mediated Inflammasome Activation in an NS3-dependent Manner
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Gim E, Shim DW, Hwang I, Shin OS, Yu JW
- KMID: 2466610
- Immune Netw.
- 2019 Dec;19(6):e40.
- doi: 10.4110/in.2019.19.e40
Zika virus (ZIKV) is a mosquito-borne flavivirus associated with severe neurological disorders including Guillain-Barré syndrome and microcephaly. The host innate immune responses against ZIKV infection are essential for protection; however,... -
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- Understanding Vulnerable Plaques: Current Status and Future Directions
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Lee KY, Chang K
- KMID: 2464291
- Korean Circ J.
- 2019 Dec;49(12):1115-1122.
- doi: 10.4070/kcj.2019.0211
The main cause of acute myocardial infarction is plaque rupture accompanied by superimposed coronary thrombosis. Thin-cap fibroatheromas (TCFAs) have been suggested as a type of lesion with a vulnerability that... -
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- A Case of an Isolated Peripheral Giant Cell Granuloma in the Parotid Gland
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Kim SJ, Yun JH, Park S, Kim HS
- KMID: 2469234
- Korean J Head Neck Oncol.
- 2019 Nov;35(2):39-43.
- doi: 10.21593/kjhno/2019.35.2.39
Peripheral giant cell granuloma (PGCG) is an benign non-neoplastic lesion most commonly occurring in oral cavity but extraoral PGCG is extremely rare. Recently, we experienced a case of an isolated... -
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- Perivascular Stem Cells Suppress Inflammasome Activation during Inflammatory Responses in Macrophages
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Kim J, Kim WJ, Ha KS, Han ET, Park WS, Yang SR, Hong SH
- KMID: 2465882
- Int J Stem Cells.
- 2019 Nov;12(3):419-429.
- doi: 10.15283/ijsc19115
BACKGROUND AND OBJECTIVES: Perivascular stem cells (PVCs) have been identified as precursors of mesenchymal stem cells (MSCs) that offer promising prospects for application in the development of cellular therapies. Although... -
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- Rhodanthpyrone A and B play an anti-inflammatory role by suppressing the nuclear factor-κB pathway in macrophages
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Kim KS, Han CY, Han YT, Bae EJ
- KMID: 2461042
- Korean J Physiol Pharmacol.
- 2019 Nov;23(6):493-499.
- doi: 10.4196/kjpp.2019.23.6.493
Macrophage-associated inflammation is crucial for the pathogenesis of diverse diseases including metabolic disorders. Rhodanthpyrone (Rho) is an active component of Gentiana rhodantha, which has been used in traditional Chinese medicine... -
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