Korean J Pediatr.
2009 Oct;52(10):1082-1089. 10.3345/kjp.2009.52.10.1082.
Recent concepts on vitamin D in children and adolescents
- Affiliations
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- 1Committee on Nutrition, Korean Pediatric Society, Korea.
- 2Department of Pediatrics, Seoul National University College of Medicine Seoul National University Bundang Hospital, Seongnam, Korea.
- 3Department of Pediatrics, Ewha Womans University School of Medicine, Seoul, Korea. jwseo@ewha.ac.kr
- 4Department of Pediatrics, Hanyang University College of Medicine, Seoul, Korea.
- 5Department of Pediatrics, Chungnam National University School of Medicine, Daejeon, Korea.
- 6Department of Pediatrics, Gachon University, Gil Hospital, Incheon, Korea.
- 7KSCH Pediatric Clinic, Chung-Ju, Korea.
- 8Department of Pediatrics, Seoul Metropolitan Dong-bu Hospital, Seoul, Korea.
- 9Department of Pediatrics, Seoul National University College of Medicine, Seoul Metropolitan Boramae Hospital, Seoul, Korea.
- 10Department of Nutritional Science, Maeil Daires Co., Ltd, Seoul, Korea.
- 11Department of Pediatrics, Youngnam University College of Medicine, Daegu, Korea.
- KMID: 2281040
- DOI: http://doi.org/10.3345/kjp.2009.52.10.1082
Abstract
- Vitamin D is an important fat-soluble vitamin that functions as a prohormone and affects bone mineralization and calcium homeostasis. Vitamin D deficiency causesboth musculoskeletal manifestations, including rickets, and extra-musculoskeletal symptoms. Because vitamin D is naturally present in only some foods, intake of daily foods cannot meet the dietary reference intake for vitamin D. Sunlight is the main source of vitamin D in humans therefore, the lack of sunlight can easily cause vitamin D deficiency in children and adolescents. Vitamin D deficiency can be diagnosed on the basis ofits typical clinical manifestation, laboratory tests, and radiologic findings. Detection of vitamin D deficiency in children or adolescents necessitates the simultaneous administration of vitamin D and calcium supplements. To prevent vitamin D deficiency, 200 IU of daily vitamin D intake is recommended in infants, and 400 IU of daily vitamin D intake is recommended in Korean children and adolescents.
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