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Vitamin D deficiency is a public health emergency among Indonesian children and adolescents: a systematic review and meta-analysis of prevalence

Octavius GS, Shakila A, Meliani M, Halim A

Purpose: This study aimed to describe the prevalence of vitamin D deficiency in Indonesian children and adolescents. Methods: This was a meta-analysis of prevalence using the Hartung-Knapp-Sidik-Jonkman method with a random...
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Effect of cinacalcet-mediated parathyroid hormone reduction on vitamin D metabolism in high-fat dietinduced obese mice

Kim TY, Park CY, Han SN

Purpose: Obesity is associated with alterations in vitamin D metabolism and elevation of parathyroid hormone (PTH). Increased PTH level in obesity is likely one of the factors contributing to the...
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Cardiovascular Impact of Calcium and Vitamin D Supplements: A Narrative Review

Zarzour F, Didi A, Almohaya M, Kendler D

Calcium and vitamin D play an important role in mineral homeostasis and the maintenance of skeletal health. Calcium and vitamin D supplements have been widely used for fracture prevention in...
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Effect of Vitamin D on YKL-40: Rat Hypercholesterolemia Model

Kocabas R

Background and Objectives: YKL-40 is considered to be associated with cardiovascular disease (CVD). In this study, the effect of serum 25(OH) vitamin D [25(OH)VitD] differences between groups on YKL-40 was...
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Prevention of Osteoporosis in Patients With Breast Cancer Treated With Aromatase Inhibitor Combined With Calcium/Vitamin D Supplements

Yang S, Park K, Kim M, Jang W, Song B, Keum H, Kang B, Lee J

Purpose: Tamoxifen and aromatase inhibitor (AI) are used for hormone therapy for hormone-positive breast cancer, and AI is well known to decrease bone mineral density (BMD). The authors compared the...
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Efficacy of plain cholecalciferol versus ergocalciferol in raising serum vitamin D level in Thai female healthcare workers

Amphansap T, Therdyothin A, Stitkitti N, Nitiwarangkul L, Phiphobmongkol V

Objectives To compare the efficacy of cholecalciferol and ergocalciferol in raising 25-hydroxyvitamin D (25(OH)D) level in Thai female healthcare workers. Methods A randomized control trial was conducted in healthy female healthcare workers. Randomization...
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Serum 25-hydroxyvitamin D3 is associated with homocysteine more than with apolipoprotein B

Kim NK, Jung MA, Choi Bh, Joo NS

BACKGROUND/OBJECTIVES: The incidence of cardiovascular diseases (CVDs) has increased worldwide. Although a low serum vitamin D level is known to be associated with the risk of CVD, the mechanism is...
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Vitamin D intake and bone mineral density in Korean adults: analysis of the 2009–2011 Korea National Health and Nutrition Examination Survey

You H, Shin HR, Song S, Ly SY

BACKGROUND/OBJECTIVES: The prevalence of vitamin D deficiency in Koreans is quite high; however, until recently, Korean National Health and Nutrition Survey (KNHANES) had not analyzed the vitamin D intake among...
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Position Statement: Vitamin D Intake to Prevent Osteoporosis and Fracture in Adults

Han A, Park Y, Lee YK, Park SY, Park CY

Adequate vitamin D status is essential for bone health. New randomized controlled trials investigating the effect of vitamin D supplementation on bone health have recently been published. This position statement...
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Changes in the Serum Levels of Parathyroid Hormone and Bone Metabolites in Two Serial Samples with Different Vitamin D Status

Park PW, Park IK

Background: Vitamin D increases serum calcium levels by promoting calcium absorption in intestines. Vitamin D deficiency raises the serum levels of parathyroid hormone (PTH) and bone metabolites. Generally, vitamin D...
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Decreased vitamin D-binding protein level portends poor outcome in acute-on-chronic liver failure caused by hepatitis B virus

Wu D, Rao Q, Xie Z, Zhu X, Che Y, Wu J, Gao H, Zhang J, Hou Z, Cheng X, Sun Z

Background/Aims: Acute-on-chronic liver failure (ACLF) is a catastrophic illness. Few studies investigated the prognostic value of vitamin D-binding protein (VDBP) for hepatitis B virus (HBV)-related ACLF (HBV-ACLF) resulted in conflicting...
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Vitamin D and Colorectal Cancer: Current Perspectives and Future Directions

Na SY, Kim KB, Lim YJ, Song HJ

Vitamin D is considered to be the main mediator of the beneficial effects of sun exposure. In humans, highest expression of Vitamin D receptors is found in the intestinal tract....
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Effectiveness of prophylactic calcium and vitamin D supplementation for preventing post-thyroidectomy hypocalcemia: a meta-analysis

Moon H, Seok JW, Kim K, Kim HY, Park MK, Kim IJ, Pak K, Suh S

Background: Postsurgical hypocalcemia is the most common and troublesome consequence of thyroidectomy. We investigated the potential role of routine calcium or vitamin D supplementation in preventing postsurgical hypocalcemia. Methods: We...
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Beneficial Role of Vitamin D on Endothelial Progenitor Cells (EPCs) in Cardiovascular Diseases

Sen A, Vincent V, Thakkar H, Abraham R, Ramakrishnan L

Cardiovascular diseases (CVDs) are the leading cause of death in the world. Endothelial progenitor cells (EPCs) are currently being explored in the context of CVD risk. EPCs are bone marrow...
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Breastfeeding and vitamin D

Heo JS, Ahn YM, Kim ARE, Shin SM, for the Korean Society of Breastfeeding Medicine

The recent re-emergence of vitamin D deficiency (VDD) and rickets among breastfed infants without adequate sunlight exposure and vitamin D supplementation has been reported worldwide. Breastfed infants are particularly vulnerable...
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The Efficacy of Selective Estrogen Receptor Modulators Monotherapies in Postmenopausal Women with Osteopenia

Kim KW, Kim YI, Kim KC

Background: The impact of osteopenia as a risk factor for fractures is underrecognized. Moreover, the efficacy of selective estrogen receptor modulators (SERMs) in postmenopausal women with osteopenia is limited. This...
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Raloxifene/Vitamin D Combination Therapy vs. Raloxifene Monotherapy on Serum 25-Hydroxy-Vitamin D Level among Postmenopausal Women with Osteoporosis or Osteopenia: A Randomized Controlled Trial

Lee YB, Baek KH, Chung HY, Byun DW, Min YK

Background: We compared the efficacy of a fixed dose combination of raloxifene 60 mg/vitamin D 800 IU to raloxifene 60 mg alone on vitamin D status, as indicated by change...
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Vitamin D Status and Bone Health in Postmenopausal Women Working in Greenhouses

Jo J, Lee YJ,  Seo H,  Kang M,  Cho I, Choi W, Kim S, Cho MC

Objectives: Greenhouse workers synthesize less vitamin D because ultraviolet light is blocked by the vinyl that covers the greenhouses. This study aimed to investigate the vitamin D status and bone...
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Dexamethasone, but Not Vitamin D or A, Dampens the Inflammatory Neutrophil Response to Protect Atrisk COVID-19 Patients

Hafkamp FM, Mol S, Waqué I, Jong ECD

Dexamethasone (DEX) was the first drug shown to save lives of critically ill coronavirus disease 2019 (COVID-19) patients suffering from respiratory distress. A hyperactivated state of neutrophils was found in...
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Vitamin D Attenuates Pain and Cartilage Destruction in OA Animals via Enhancing Autophagic Flux and Attenuating Inflammatory Cell Death

Jhun J, Woo JS, Kwon JY, Na HS, Cho KH, Kim SA, Kim SJ, Moon SJ, Park SH, Cho ML

Osteoarthritis (OA) is the most common form of arthritis associated with ageing. Vitamin D has diverse biological effect on bone and cartilage, and observational studies have suggested it potential benefit...
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