Korean J Otolaryngol-Head Neck Surg.
1997 Aug;40(8):1079-1084.
A Clinical Study on Primary Ciliary Dyskinesia
- Affiliations
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- 1Department of Otolaryngology, College of Medicine, Hanyang University, Seoul, Korea.
Abstract
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BACKGROUND: Since ciliary dysfunction of the respiratory system impair mucosal ciliary clearance, it is associated with recurrent or persistent upper respiratory infections, chronic bronchitis, chronic sinusitis, recurrent pneumonia, recurrent otitis media, bronchiectasis and chronic rhinitis. Primary ciliary dyskinesia has a familial tendency and it is known to have autosomal recessive trait, and rarely acquired trait.
OBJECTIVES
We had this study in order to inspect whether primary ciliary dyskinesia is associated with recurrent or persistent upper respiratory problems or not. MATERIAL AND METHODS: From May 1995 through April 1996, by electron microscopy of the nasal mucosa, the authors analysed nine patients who had recurrent or persistent respiratory symptoms.
RESULTS
Electron microscopic findings revealed primary ciliary dyskinesia in 4 patients with the symptoms of upper respiratory tract problems.
CONCLUSION
It is concluded that nasal mucosal biopsy may be necessary for rule out primary ciliary dyskinesia in the patients with recurrent respiratory infections.
