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Particulate Matter 2.5 Causes Deficiency in Barrier Integrity in Human Nasal Epithelial Cells

Xian M, Ma S, Wang K, Lou H, Wang Y, Zhang L, Wang C, Akdis CA

PURPOSE: The effect of air pollution-related particulate matter (PM) on epithelial barrier function and tight junction (TJ) expression in human nasal mucosa has not been studied to date. This study...
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Antiallergic Effect of Hizikia fusiformis in an Ovalbumin-Induced Allergic Rhinitis Mouse Model

Zhang YL, Shin HJ, Lee JH, Lee J

OBJECTIVES: The extract of Hizikia fusiformis is known to exhibit anticancer, antiatopic and antioxidant activities. We aimed to investigate the extract of H. fusiformis on allergic rhinitis inflammation in a...
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Intranasal teeth in a 3-year-old child with Smith-Lemli-Opitz syndrome

Shim SH

Smith–Lemli–Opitz syndrome (SLOS) is a rare autosomal recessive genetic disorder accompanied with congenital anomalies and mental impairment. Clefts of the hard and/or soft palate, small tongue, broad alveolar ridges, and...
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Topographical variations of the incisive canal and nasopalatine duct in human fetuses

Kim JH, Shibata S, Abe H, Murakami G, Rodríguez-Vázquez JF

The incisive canal for nerves and vessels is generally thought to run along a suture between the incisive bone (IN) and maxilla. In contrast, there was a report saying the...
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Points to consider before the insertion of maxillary implants: the otolaryngologist's perspective

Kim SW, Lee IH, Kim SW, Kim DH

Maxillary implants are inserted in the upward direction, meaning that they oppose gravity, and achieving stable support is difficult if the alveolar bone facing the maxillary sinus is thin. Correspondingly,...
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Neutrophils as a Protagonist and Target in Chronic Rhinosinusitis

Wang H, Pan L, Liu Z

Neutrophils have traditionally been acknowledged as the first immune cells that are recruited to inflamed tissues during acute inflammation. By contrast, their importance in the context of chronic inflammation has...
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Floating septum technique: easy and safe method maxillary sinus septa in sinus lifting procedure

Jung J, Hwang BY, Kim BS, Lee JW

BACKGROUND: The presence of septa increases the risk of Schneiderian membrane perforation during sinus lift procedure, and therefore, the chance of graft failure increases. We present a safe method of...
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Role of Interleukin-10-Expressing B Cells on the Pathophysiology of Chronic Sinusitis

Park HS, Park SK, Yeon SH, Xu J, Rha KS, Kim YM

BACKGROUND AND OBJECTIVES: Many kinds of inflammatory cells and cytokines are suggested to be related with pathophysiology of chronic rhinosinusitis with nasal polyp (CRSwNP), but its mechanism is not yet...
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Evaluation and Treatment of Nasal Obstruction Developed after Rhinoplasty

Yi JS, Jin HR

Nasal airway obstruction is one of the most frequent causes of revision rhinoplasty despite the golden rule that nasal function should not be sacrificed because of cosmetic reason. Nasal function...
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Usefulness of indirect open reduction via a transconjunctival approach for the treatment of nasal bone fracture associated with orbital blowout fracture

Kim TH, Kang SJ, Jeon SP, Yun JY, Sun H

BACKGROUND: Nasal fracture and orbital blowout fracture often occur concurrently in cases of midface blunt trauma. Generally, these multiple fractures treatment is surgery, and typically, the nasal bone and orbit...
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Saddle Nose Deformity as a Result of an Aseptic Nasal Abscess Accompanied by Ulcerative Colitis and Pyoderma Gangrenosum

Chang J

Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) that causes granulomatous inflammation in the mucous membrane of the intestinal tract, especially in the colon. Additionally, UC can be...
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Correlation between nasal mucosal thickness around the lacrimal sac fossa and surgical outcomes in endonasal dacryocystorhinostomy

Yoo JH, Kim CZ, Nam KY, Lee SU, Lee JH, Lee SJ

OBJECTIVES: To identify the relationship between surgical success rate and preoperative nasal mucosal thickness around the lacrimal sac fossa, as measured using computed tomography. METHODS: We reviewed 33 eyes from 27...
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Efficacy and Safety of Autologous Stromal Vascular Fraction in the Treatment of Empty Nose Syndrome

Kim DY, Hong HR, Choi EW, Yoon SW, Jang YJ

OBJECTIVES: Regenerative treatment using stem cells may serve as treatment option for empty nose syndrome (ENS), which is caused by the lack of turbinate tissue and deranged nervous system in...
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Efficacy of Nasal Cellulose Powder in the Symptomatic Treatment of Allergic Rhinitis: A Randomized, Double-Blind, Placebo-Controlled Trial

Manuyakorn W, Klangkalya N, Kamchaisatian W, Benjaponpita S, Sasisakulporn C, Jotikasthira W

PURPOSE: Nasal Cellulose Powder (NCP), which can prevent from binding an allergen to nasal mucosa, may reduce allergic rhinitis (AR) symptoms in dust mite-sensitized children. This study was conducted to...
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Systemic Lupus Erythematosus Presenting as Stevens-Johnson Syndrome: A Case Report

Lee KG, Koh BY, Kwon ES, Myung KB, Kwon MH, Cheong SH

  • KMID: 2386240
  • Korean J Dermatol.
  • 2017 Jun;55(5):293-296.
Acute cutaneous lupus erythematosus (ACLE) on the face is a usual pattern of presentation. However, it can rarely present with a generalized distribution. A hyperacute form of ACLE can mimic...
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The Efficacy of Coblator in Turbinoplasty

Lee KC, Cho JM, Kim SK, Lim KR, Lee SY, Park SS

BACKGROUND: Turbinate hypertrophy is one of the common causes of chronic nasal obstruction. In principle, therapeutic guidelines recommend medical treatment. Failure to treat turbinate thickening despite drug therapy may indicate...
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Anti-Interleukin-9 Antibody Increases the Effect of Allergen-Specific Immunotherapy in Murine Allergic Rhinitis

Shin JH, Kim DH, Kim BY, Kim SW, Hwang SH, Lee J, Kim SW

PURPOSE: Interleukin (IL)-9 induces allergic responses; however, the roles of anti-IL-9 antibody in the induction of tolerance remain unclear. This study investigated the effects of anti-IL-9 antibody on oral tolerance...
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The Role of IL-17 in a Lipopolysaccharide-Induced Rhinitis Model

Bae JS, Kim JH, Kim EH, Mo JH

PURPOSE: Lipopolysaccharide (LPS) is a cell wall component of Gram-negative bacteria and important for pro-inflammatory mediators. This study aimed to establish a rhinitis model using ovalbumin (OVA) and LPS in...
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Vγ1+γδT Cells Are Correlated With Increasing Expression of Eosinophil Cationic Protein and Metalloproteinase-7 in Chronic Rhinosinusitis With Nasal Polyps Inducing the Formation of Edema

Yang LY, Li X, Li WT, Huang JC, Wang ZY, Huang ZZ, Chang LH, Zhang GH

PURPOSE: We have found that expression of γδT cells is increased in pathological mucosa of chronic rhinosinusitis with nasal polyps (CRSwNP) compared with normal nasal mucosa. This increase is correlated...
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Neonatal Immune State Is Influenced by Maternal Allergic Rhinitis and Associated With Regulatory T cells

Tan L, Ou J, Tao Z, Kong Y, Xu Y

PURPOSE: Maternal influences contribute to the origin of allergic diseases, but the mechanisms are not clear. The current literature prompted the role of epigenetics in the development of allergic diseases....
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