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Role of IL-17A in Chronic Rhinosinusitis With Nasal Polyp

Ryu G, Bae JS, Kim JH, Kim EH, Lyu L, Chung YJ, Mo JH

PURPOSE: Th17-associated inflammation is increased in chronic rhinosinusitis with nasal polyp (CRSwNP), and is associated with disease severity and steroid resistance. Overexpressed interleukin (IL)-17A affects CRSwNP by tissue remodeling, eosinophilic...
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Evaluation of Neo-Osteogenesis in Eosinophilic Chronic Rhinosinusitis Using a Nasal Polyp Murine Model

Khalmuratova R, Lee M, Park JW, Shin HW

PURPOSE: Osteitis refers to the development of new bone formation and remodeling of bone in chronic rhinosinusitis (CRS) patients; it is typically associated with eosinophilia, nasal polyps (NPs), and recalcitrant...
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MR Findings of Fungus Ball: Significance of High Signal Intensity on T1-Weighted Images

Kim SC, Ryoo I, Shin JM, Suh S, Jung HN, Shin SU

BACKGROUND: Central dark-signal intensity with high-signal, hypertrophic mucosal wall of paranasal sinuses on T2-weighted images (T2WI) is a characteristic magnetic resonance imaging (MRI) feature of sinonasal fungus ball. However, this...
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Elastase-Positive Neutrophils Are Associated With Refractoriness of Chronic Rhinosinusitis With Nasal Polyps in an Asian Population

Kim DK, Kim JY, Han YE, Kim JK, Lim HS, Eun KM, Yang SK, Kim DW

PURPOSE: Various immune cells, including eosinophils and neutrophils, are known to contribute to the development of chronic rhinosinusitis with nasal polyps (CRSwNP). However, the current understanding of the role of...
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In-Depth, Proteomic Analysis of Nasal Secretions from Patients With Chronic Rhinosinusitis and Nasal Polyps

Kim YS, Han D, Kim J, Kim DW, Kim YM, Mo JH, Choi HG, Park JW, Shin HW

PURPOSE: Chronic rhinosinusitis (CRS) is a complex immunological condition, and novel experimental modalities are required to explore various clinical and pathophysiological endotypes; mere evaluation of nasal polyp (NP) status is...
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Immunological Characteristics in Refractory Chronic Rhinosinusitis with Nasal Polyps Undergoing Revision Surgeries

Ryu G, Kim DK, Dhong HJ, Eun KM, Lee KE, Kong IG, Kim H, Chung SK, Kim DY, Rhee CS, Cho SH, Hong SD, Kim DW

PURPOSE: Despite medical and surgical treatments, some cases of nasal polyps (NP) exhibit recidivism. However, the endotype of refractory chronic rhinosinusitis with NP (CRSwNP) remains unclear. Therefore, the objective of...
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Biomarkers in Chronic Rhinosinusitis with Nasal Polyp: Personalized Medicine Based on Endotype

Song Y, Cho SW

Chronic rhinosinusitis (CRS) is divided into CRS with nasal polyp (CRSwNP) and CRS without nasal polyp (CRSsNP) according to the presence of a nasal polyp. Some of the CRSwNP patients...
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Epidural Abscess Caused by Eikenella corrodens in a Previously Healthy Child

Kim YK, Han MS, Yang SI, Yun KW, Han DH, Kim JY, Choi EH

Eikenella corrodens rarely causes invasive head and neck infections in immunocompetent children. We report a case of epidural abscess caused by E. corrodens in a previously healthy 13-year-old boy who...
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Headache with Ptosis Attributed to Fungal Sinusitis

Kim Y, Lee HC, Park SP, Seo JG

No abstract available.
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Eosinophilic Granulomatosis with Polyangiitis: Experiences in Korean Patients

Choi CB, Park YB, Lee SW

Eosinophilic granulomatosis with polyangiitis (EGPA) is one form of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. Identical to what has been called Churg-Strauss syndrome, EGPA exhibits both allergic and vasculitis features. EGPA...
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The Differences in Paranasal Sinus Pneumatization after Adolescence in Korean

Kang M, Mo JH, Chung YJ

BACKGROUND AND OBJECTIVES: The embryological development of paranasal sinuses has been revealed by previous articles although few studies have reported on the differences of paranasal sinus pneumatization according to age...
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Revisiting the Clinical Scoring System for the Prognosis of Chronic Rhinosinusitis with Nasal Polyps

Kim JY, Han YE, Seo Y, Choe G, Kim MK, Huh G, Cho D, Yang SK, Kang SH, Kim DW

PURPOSE: To evaluate the Japanese Epidemiological Survey of Refractory Eosinophilic Chronic Rhinosinusitis (JESREC) classification, a clinical scoring system, for predicting disease control status in chronic rhinosinusitis with nasal polyps (CRSwNP)...
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Frontal Sinusitis Presenting as Cluster-Like Headache

Seo J, Kim BS, Jung YI, Lee HJ, Yu HJ, Jeong EH, Sunwoo M, Park YK

No abstract available.
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The Effect of Long-Term Follow up on Outcome of Pediatric Endoscopic Sinus Surgery

Kim S, Chung YJ, Mo JH

BACKGROUND AND OBJECTIVES: Chronic pediatric sinusitis continues to be a challenging problem to otolaryngologists and has been reported to show worse prognosis than that of adults. However, most studies were...
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Clinical Usefulness of Trasseptal Transsphenoidal Approach for Pituitary Tumors with Septal Cartilage Removal and Replacement via Modified Killian Incision: Review of 42 Cases

Kim SY, Yang BW, Lee YW, Lee KC

BACKGROUND AND OBJECTIVES: The conventional transseptal transsphenoidal approach can inhibit visualization of the surgical field and may change the shape of external nose. We used the transseptal transsphenoidal technique to...
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A Case of Septal Abscess and Sphenoid Sinusitis after Dental Implant

Lee J, Kim SJ, Choi MS

A nasal septal abscess results from the collection of purulent fluid between the cartilage of bony septum and overlying mucoperichondrium or mucoperiosteum. Unless early diagnosis and surgical treatment are performed,...
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Comparison Between Signature Cytokines of Nasal Tissues in Subtypes of Chronic Rhinosinusitis

Kim DK, Eun KM, Kim MK, Cho D, Han SA, Han SY, Seo Y, Lee DH, Cho SH, Kim DW

PURPOSE: Endotype in chronic rhinosinusitis (CRS) has been established in the last decade. However, the exact immunologic profile of CRS still has controversy because it has a considerable immunologic heterogeneity....
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Dentistry and otorhinolaryngology cooperative therapy of chronic maxillary sinusitis: Case series study

Yu HC, Yun PY, Chang NH, Kim YK

For the maxillary sinus to normally function, the ventilation and drainage should be well maintained. The natural ostium of the maxillary sinus could be blocked owing to various reasons. In...
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Oculomotor and Abducens Nerve Palsy Complicated by Cavernous Sinus Thrombophlebitis Resulting from Acute Sinusitis

Kang JY, Kim JJ, Choi IJ, Lee MC

Cavernous sinus thrombophlebitis is a rare complication of paranasal sinusitis. The disease can result in a fatal outcome if not treated with proper antibiotics or surgical intervention. Recently, we experienced...
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Points to consider before the insertion of maxillary implants: the otolaryngologist's perspective

Kim SW, Lee IH, Kim SW, Kim DH

Maxillary implants are inserted in the upward direction, meaning that they oppose gravity, and achieving stable support is difficult if the alveolar bone facing the maxillary sinus is thin. Correspondingly,...
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