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Primary Nasal Epithelial Cells From Allergic and Non-allergic Individuals Show Comparable Barrier Function

Waltl EE, Stanek V, Mueller CA, Kiss R, Eckl-Dorna J, Valenta R, Niederberger V

Previous reports suggested that ex vivo cultured primary nasal epithelial cells from allergic patients differ from those from non-allergic individuals by genuinely reduced barrier function. By contrast, we found that...
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Allergenic Pollen Calendar in Korea Based on Probability Distribution Models and Up-to-Date Observations

Shin JY, Han MJ, Cho C, Kim KR, Ha JC, Oh JW

PURPOSE: The pollen calendar is the simplest forecasting method for pollen concentrations. As pollen concentrations are liable to seasonal variations due to alterations in climate and land-use, it is necessary...
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Aligning the Good Practice MASK With the Objectives of the European Innovation Partnership on Active and Healthy Ageing

Bousquet J, Farrell J, Illario M, the ARIA-MASK study group

The reference sites of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) were renewed in 2019. The DG Santé good practice Mobile Airways Sentinel networK was...
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Comparison of the risks of combustible cigarettes, e-cigarettes, and heated tobacco products

Cho HJ

E-cigarettes (ECs) and heated tobacco products (HTPs) have become popular in Korea; hence, it is important to determine whether ECs and HTPs are less hazardous than combustible cigarettes (CCs). In...
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Natural History of Chronic Urticaria in Korea

Chung BY, Um JY, Kang SY, Kim HO, Park CW

BACKGROUND: Data on the natural history and prognostic variables of chronic urticaria (CU) are rare and information about spontaneous remission of CU is limited. OBJECTIVE: This study evaluated the natural history...
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Asia Pacific Association of Allergy Asthma and Clinical Immunology White Paper 2020 on climate change, air pollution, and biodiversity in Asia-Pacific and impact on allergic diseases

Pawankar R, Wang JY, Wang IJ, Thien F, Chang YS, Latiff AH, Fujisawa T, Zhang L, Thong BY, Chatchatee P, Leung TF, Kamchaisatian W, Rengganis , Yoon HJ, Munkhbayarlakh S, Recto MT, Neo AG, Le Pham D, Lan LT, Davies JM, Oh JW

Air pollution, climate change, and reduced biodiversity are major threats to human health with detrimental effects on a variety of chronic noncommunicable diseases in particular respiratory and cardiovascular diseases. The...
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Association between fruit and vegetable allergies and pollen-food allergy syndrome in Japanese children: a multicenter cross-sectional case series

Takemura Y, Takaoka Y, Arima T, Masumi H, Yamasaki K, Nagai M, Sugimoto K, Hamada M, Takano T, Doi M, Kawakami T, Kameda M

BACKGROUND: Recently, the prevalence of food allergies during childhood is increasing, with fruits being common allergens. However, data on allergens that cause fruit and vegetable allergies and pollen-food allergy syndrome...
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Fractional exhaled nitric oxide and forced expiratory volume in 1 second/forced vital capacity have predictive value of asthma exacerbation in Korean school children

Kang MG, Yoon SA, Sim JH, Woo SI

BACKGROUND: The incidence of asthma exacerbation (AE) and the predictive value of spirometry and fractional exhaled nitric oxide (FeNO) in school children have not been evaluated. OBJECTIVE: We sought to evaluate...
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A 5-year retrospective review of children with peanut allergy in the largest paediatric hospital in Singapore

Lee MP, Saffari SE, Loh W, Goh SH, Goh A, Chiang WC, Chong KW

BACKGROUND: The prevalence of peanut allergy (PA) among children has increased significantly over the past decade. Even though the prevalence of PA in Singapore is considered low, peanut is the...
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Clinical characteristics of allergic rhinitis and nonallergic rhinitis in Korean children

Won NH, Park SH, Ahn SH, Kim CB, Kwon JH, Seo WH, Song DJ, Yoo Y

PURPOSE: Recently, the prevalence of allergic rhinitis (AR) in Korean children has been increased. The aim of this study was to investigate the clinical characteristics of rhinitis and to compare...
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The diagnostic usefulness and correlation of nasal eosinophil count and percentage in children with rhinitis

Yoon KH, Kim K, Yoon JS, Kim HH

PURPOSE: Allergic rhinitis is the most common atopic disease and the most common chronic disease of children. Eosinophil count and percentage in nasal smear are useful for differential diagnosis of...
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Update on the Management of Nonsteroidal Anti-Inflammatory Drug Hypersensitivity

Yeung WY, Park HS

The clinical phenotypes of nonsteroidal anti-inflammatory drug (NSAID) hypersensitivity are heterogeneous with various presentations including time of symptom onset, organ involvements, and underlying pathophysiology. Having a correct diagnosis can be...
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Deep Neural Network-Based Concentration Model for Oak Pollen Allergy Warning in South Korea

Seo YA, Kim KR, Cho C, Oh JW, Kim TH

PURPOSE: Oak is the dominant tree species in Korea. Oak pollen has the highest sensitivity rate among all allergenic tree species in Korea. A deep neural network (DNN)-based estimation model...
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Reversal of Olfactory Disturbance in Allergic Rhinitis Related to OMP Suppression by Intranasal Budesonide Treatment

Jung AY, Kim YH

PURPOSE: We evaluated the severity of olfactory disturbance (OD) in the murine model of allergic rhinitis (AR) and local allergic rhinitis (LAR) in mice. We also investigated the therapeutic effect...
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Risk Factors and Comorbidities Associated With the Allergic Rhinitis Phenotype in Children According to the ARIA Classification

Jung S, Lee SY, Yoon J, Cho HJ, Kim YH, Suh DI, Yang SI, Kwon JW, Jang GC, Sun YH, Woo SI, Youn YS, Park KS, Lee E, Cho HJ, Kook MH, Yi HR, Chung HL, Kim JH, Kim HY, Jung JA, Woo HO, Lee JK, Chang WS, Do NH, Cho H, Hong SJ

PURPOSE: Data are lacking on the association between the allergic rhinitis (AR) phenotype and sensitization to specific allergens or bronchial hyperresponsiveness (BHR) in children. We here investigated risk factors and...
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Particulate Matter 2.5 Causes Deficiency in Barrier Integrity in Human Nasal Epithelial Cells

Xian M, Ma S, Wang K, Lou H, Wang Y, Zhang L, Wang C, Akdis CA

PURPOSE: The effect of air pollution-related particulate matter (PM) on epithelial barrier function and tight junction (TJ) expression in human nasal mucosa has not been studied to date. This study...
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Elastase-Positive Neutrophils Are Associated With Refractoriness of Chronic Rhinosinusitis With Nasal Polyps in an Asian Population

Kim DK, Kim JY, Han YE, Kim JK, Lim HS, Eun KM, Yang SK, Kim DW

PURPOSE: Various immune cells, including eosinophils and neutrophils, are known to contribute to the development of chronic rhinosinusitis with nasal polyps (CRSwNP). However, the current understanding of the role of...
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Association between use of humidifier disinfectant and allergic rhinitis in Korean children: a cross-sectional study based on the eighth Panel Study on Korean Children (PSKC)

Koh TH, Park JT, Kwon D, Kwak K

BACKGROUND: Rhinitis was the most frequently diagnosed disorder among users of humidifier disinfectants (HDs). The aim of our study was to investigate on the relationship between allergic rhinitis (AR) and...
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Association between green areas and allergic disease in Korean adults: a cross-sectional study

Kim HJ, Min JY, Kim HJ, Min KB

BACKGROUND: Although many epidemiological studies have reported the inverse associations between greenness and health outcomes, inconsistent associations in allergic diseases remain an issue. We aimed to identify associations between greenness...
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Nasal eosinophilia and eosinophil peroxidase in children and adolescents with rhinitis

Choi Y, Jeon H, Yang EA, Yoon JS, Kim HH

BACKGROUND: Researchers have shown that eosinophil peroxidase (EPO) is a relatively accurate marker of eosinophilia and eosinophil activity. However, its use as a marker of eosinophilic inflammation in nasal secretions...
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