J Vet Sci.  2023 Jul;24(4):e57. 10.4142/jvs.23029.

Siewert–Kartagener’s syndrome in a dog

• Jung R
• Choi J
• Bae H
• Jung DI
• Cho KO
• Yu D

• KMID: 2545109
• DOI: http://doi.org/10.4142/jvs.23029

Abstract

Siewert–Kartagener’s syndrome, a type of primary ciliary dyskinesia, is a complex disease comprising situs inversus, rhinosinusitis, and bronchiectasis. Situs inversus totalis is a condition in which all organs in the thoracic and abdominal cavities are reversed. Furthermore, primary ciliary dyskinesia, an autosomal genetic disease, may coexist with situs inversus totalis. Reports on Siewert–Kartagener’s syndrome in veterinary medicine are limited. We report a rare case of primary ciliary dyskinesia with Siewert-Kartagener’s syndrome in a dog, concurrently infected with canine distemper virus and type-2 adenovirus. This case highlights that situs inversus totalis can cause primary ciliary dyskinesia, and concurrent infections are possible.

Keyword

Adenovirus E3 proteins; ciliary motility disorders; distemper virus, canine; kartagener syndrome; situs inversus