Tuberc Respir Dis.
2002 Oct;53(4):457-462. 10.4046/trd.2002.53.4.457.
A Case of Kartagener's Syndrome with Various Ultrastructural Defects
- Affiliations
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- 1Division of pulmonology, Department of Medicine, Sungkyunkwan University School of Medicine, Masan Samsung Medical Center, Masan, Korea. kangkw@samsung.co.kr
- 2Department of Pathology, Keimyung University, Taegu, Korea.
- KMID: 1970604
- DOI: http://doi.org/10.4046/trd.2002.53.4.457
Abstract
- Kartagener's syndrome is an inherited condition characterized by triad of chronic paranasal sinusitis, situs inversus, and bronchiectasis. Since 1976, Afzelius found a lack of dynein arm in immotile spermatozoa by electron microscopy, numerous recent studies have focused on the ultrastructural defect in the cilia and reported that the variety type of ultrastructural defect in immotile cilia syndrome. We report a female patient who had the Kartagener's triad with rare multiple ultrastructural defect of cilia in one patient. The electron microscopic examination showed partial dynein arm defect, loss of radial spoke, microtubular transposition, and giant cilia.
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