Allergy Asthma Respir Dis.  2013 Mar;1(1):67-72. 10.4168/aard.2013.1.1.67.

The association between sibling and allergic rhinitis in adolescents

Affiliations
  • 1Department of Pediatrics, Korea Cancer Center Hospital, Seoul, Korea.
  • 2Department of Pediatrics, Kosin University Gospel Hospital, Busan, Korea.
  • 3Department of Pediatrics, Childhood Asthma Atopy Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. sjhong@amc.seoul.kr
  • 4Department of Pediatrics, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
  • 5Department of Pediatrics, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea.
  • 6Department of Pediatrics, Inje University Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.
  • 7Department of Pediatrics, Inje University Seoul Paik Hospital, Inje University College of Medicine, Seoul, Korea.
  • 8Department of Pediatrics, Hallym Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.
  • 9Department of Pediatrics, National Health Insurance Corporation Ilsan Hospital, Goyang, Korea.
  • 10Department of Pediatrics, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.
  • 11Department of Pediatrics, Kangbuk Samsung Hospital, Sungkyunkwan University College of Medicine, Seoul, Korea.
  • 12Department of Immunology and Pathology, Allergy TF, Korea National Institute of Health, Cheongwon, Korea.

Abstract

PURPOSE
We investigated the effect of siblings on the development of allergic rhinitis (AR) in Korean adolescents.
METHODS
A cross-sectional study of adolescents (n=3,271) aged 12 to 15 years was conducted at three middle schools in Seoul. Demographic and disease-related information was obtained through a questionnaire.
RESULTS
The mean age of the subjects was 13.9+/-0.8 years comprising 48.7% males and 51.3% females. The percentage of the subjects who had ever been diagnosed with AR by physician was 30.7%. Subjects who had older sibling and who had younger sibling were 45.3% and 44.2% respectively. Subjects with older sibling were less likely to diagnose AR than subjects without older sibling (adjusted odds ratio [aOR], 0.69; 95% confidence interval [CI], 0.57 to 0.84). Subjects with older sibling, even though with family history of allergic disease had protective effect compared to subjects without older sibling (aOR, 0.62; 95% CI, 0.45 to 0.84). Subjects with younger sibling were more likely to diagnose AR than subjects without younger sibling (aOR, 1.23; 95% CI, 1.02 to 1.49).
CONCLUSION
These findings suggest that having older sibling is one of the important protective factor for the development of allergic rhinitis and having younger sibling is risk factor for allergic rhinitis in adolescents.

Keyword

Allergic rhinitis; Adolescent; Sibling

MeSH Terms

Adolescent
Aged
Cross-Sectional Studies
Female
Humans
Male
Odds Ratio
Rhinitis
Rhinitis, Allergic, Perennial
Risk Factors
Siblings

Cited by  1 articles

Research on pediatric allergic rhinitis in Korea
Kyung Suk Lee, Yeong Ho Rha
Allergy Asthma Respir Dis. 2018;6(Suppl 1):S58-S65.    doi: 10.4168/aard.2018.6.S1.S58.


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