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Licochalcone H Induces Cell Cycle Arrest and Apoptosis in Human Skin Cancer Cells by Modulating JAK2/STAT3 Signaling

Park KH, Joo SH, Seo JH, Kim J, Yoon G, Jeon YJ, Lee MH, Chae JI, Kim WK, Shim JH

Licochalcone H (LCH) is a phenolic compound synthetically derived from licochalcone C (LCC) that exerts anticancer activity. In this study, we investigated the anticancer activity of LCH in human skin...
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Primary cutaneous mucormycosis of the scalp

Seo BF, Seo JH, Yoo G

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Recent Changes in the Treatment of Helicobacter pylori Infection in Children and Adolescents

Seo JH, Park JS, Youn HS

Treatments aimed at eradicating Helicobacter pylori (H. pylori) infections in children and adolescents should be clearly beneficial. According to the updated guidelines, a 14-day triple therapy or bismuth-based triple therapy...
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Efficacy of an Integrated Training Device in Improving Muscle Strength, Balance, and Cognitive Ability in Older Adults

Roh CH, Kim DS, Kim GW, Won YH, Park SH, Seo JH, Ko MH

Objective To determine the effects of an integrated training device for strength and balance on extremity muscle strength, postural balance, and cognition in older adults using a combination with various...
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A Novel Robot-Assisted Kinematic Measure for Children with Attention-Deficit/Hyperactivity Disorder: A Preliminary Study

Min A, Kim JI, Noh HJ, Kim MS, Lee HS, Choi MT, Lee K, Seo JH, Lee GH, Kang Sk, Ahn DH

Objective Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by inattention, hyperactivity, and impulsivity. In contrast to neurocognitive measurements of inattention and impulsivity, there has been limited research regarding the...
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Luteolin inhibits H2O2 -induced cellular senescence via modulation of SIRT1 and p53

Zhu RZ, Li BS, Gao SS, Seo JH, Choi BM

Luteolin, a sort of flavonoid, has been reported to be involved in neuroprotective function via suppression of neuroinflammation. In this study, we investigated the protective effect of luteolin against oxidative...
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Advantages of Cold-knife Dissection with Adjunctive Suction Cauterization Adenotonsillectomy: A Useful and Safe Surgical Technique for Pediatric Patients

Park JM, Han JS, Kim Y, Seo JH, Park SN

Background and Objectives To introduce cold-knife dissection with adjunctive suction cauterization (CDASC) technique for pediatric adenotonsillectomy and to evaluate the advantages of this technique through short and long-term follow-up results. Subjects...
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Successful Treatment of Severe Hemolytic Disease of the Newborn Caused by Anti-Jk b

Kim GL, Kim Y, Chang YP, Seo JH, Lee MJ

Hemolytic disease of the newborn (HDN) is a condition in which maternal antibodies cross the placenta and cause hemolytic reactions. Anti-RhD was the most common cause, but with the introduction...
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Nationwide “Pediatric Nutrition Day” survey on the nutritional status of hospitalized children in South Korea

Lee YM, Ryoo E, Hong J, Kang B, Choe BH, Seo JH, Park JS, Jang HJ, Lee Y, Chang EJ, Chang JY, Lee HJ, Kim JY, Lee EH, Kim HJ, Chung JY, Choi YJ, Choi SY, Kim SC, Kang KS, Yi DY, Moon KR, Lee JH, Kim YJ, Yang HR

BACKGROUND/OBJECTIVES: To evaluate the nutritional status and prevalence of malnutrition in hospitalized children at admission and during hospitalization in South Korea. SUBJECTS/METHODS: This first cross-sectional nationwide “Pediatric Nutrition Day (pNday)” survey...
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A Case of Congenital Common Bile Duct Web Treated with Balloon Dilation under Endoscopic Retrograde Cholangiopancreatography in a Young Child

Park JS, Kim HJ, Seo JH, Youn HS

Web in common bile duct (CBD web) is very rare. It is usually asymptomatic and detected incidentally during surgery for other causes in adults. It can be congenital or acquired,...
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Effect of Heel Raise Exercise with NMES on Peroneus Longus Muscle Strength and Postural Control Ability in Subjects with Functional Ankle Instability: Randomized Controlled Trial

Seo JH, Lee JH, Lee MY

Purpose: This study examined the effects of heel raise exercises combined with neuromuscular electrical stimulation (NMES) on the muscle strength and postural control ability of subjects with functional ankle instability...
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Postoperative Clinical Outcomes of Colonic Stent Placement as Bridge-to-surgery vs. Emergency Surgery in Left-sided Malignant Colonic Obstruction

Choe EJ, Lee YK, Jeon HH, Choi JW, Park BK, Won SY, Seo JH, Lee CK, Cho YS

Background/Aims: Colonic stenting as a bridge to elective surgery is an alternative for emergency surgery in patients with acute malignant colonic obstruction. However, since its benefits are uncertain, we aimed...
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Podophyllotoxin Induces ROS-Mediated Apoptosis and Cell Cycle Arrest in Human Colorectal Cancer Cells via p38 MAPK Signaling

Lee SO, Joo SH, Kwak AW, Lee MH, Seo JH, Cho SS, Yoon G, Chae JI, Shim JH

Podophyllotoxin (PT), a lignan compound from the roots and rhizomes of Podophyllum peltatum, has diverse pharmacological activities including anticancer effect in several types of cancer. The molecular mechanism of the...
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Frequency and clinical characteristics of adverse transfusion reactions in hospitalized patients: A retrospective review of electronic medical records

Kim YH, Seo JH, Ahn KM, Yang MS, Kim SH, Cho SH, Chang YS

Purpose: Adverse transfusion reactions (ATRs) are unfavorable reactions to the transfused unit, and the severity may be different among individuals, depending upon the type of reactions and the patient’s susceptibility....
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Care Process of Recanalization Therapy for Acute Stroke during the COVID-19 Outbreak in South Korea

Kim YD, Nam HS, Sohn SI, Park H, Hong JH, Kim GS, Seo KD, Yoo J, Baek JH, Seo JH, Heo J, Baik M, Lee HS, Heo JH, on behalf of the SMART-EST Study Group

Background and Purpose We aimed to determine whether the care process and outcomes in patients with acute stroke who received recanalization therapy changed during the outbreak of coronavirus disease 2019...
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Changing prevalence of Helicobacter pylori infection in children and adolescents

Park JS, Jun JS, Seo JH, Youn HS, Rhee KH

Helicobacter pylori infection has declined over recent decades. However, its prevalence remains high, and nearly 50% of the global population has been infected. In Korea, seroprevalence has steadily decreased in...
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Risk for metabolic syndrome in the population with visceral fat area measured by bioelectrical impedance analysis

Jeon HH, Lee YK, Kim DH, Pak H, Shin SY, Seo JH

Background/Aims: To investigate whether visceral fat area (VFA) measured by bioelectric impedance analysis (BIA) was associated with metabolic syndrome in subjects with and without obesity. Methods: A total 23,202 participants who...
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New Paradigm of Pediatric Clinical Clerkship during the Epidemic of COVID-19

Lee YM, Park KD, Seo JH

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Risk Factors and Effects of Severe LateOnset Hyponatremia on Long-Term Growth of Prematurely Born Infants

Park JS, Jeong SA, Cho JY, Seo JH, Lim JY, Woo HO, Youn HS, Park CH

Purpose: Sodium is an essential nutritional electrolyte that affects growth. A low serum sodium concentration in healthy premature infants beyond 2 weeks of life is called lateonset hyponatremia (LOH). Here,...
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Changes in Seroprevalence of Helicobacter pylori Infection over 20 Years in Jinju, Korea, from Newborns to the Elderly

Park JS, Jun JS, Ryu EY, Yeom JS, Park ES, Seo JH, Lim JY, Park CH, Woo HO, Baik SC, Lee WK, Cho MJ, Rhee KH, Youn HS

Background: The objective of this study was to examine changes in the prevalence of cytotoxic-associated gene A (CagA) positive Helicobacter pylori infection in Jinju, Korea, over the last 20 years. Methods:...
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