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Nasal Nitric Oxide in the Upper Airway Inflammatory Diseases

Jeong JH

Exhaled nitric oxide (eNO) from the lower respiratory tract is used commonly in diagnosis and treatment monitoring of asthma patients. However, nasal nitric oxide (nNO) has not been widely used...
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The Similarity of Biomarkers Level between Direct Nasal Fluid and Nasal Lavage Fluid in Allergic Rhinitis Patients

Kim JS, Han SJ, Park JM, Kim SW, Eun YG, Kwon OE

Background and Objectives: Biomarkers of allergic rhinitis (AR) have been studied; however, little is known regarding their practical application in the diagnosis of AR. Previous studies collected samples using saline...
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Human Rhinovirus Infection Enhances the Th2 Environment in Allergic and Non-allergic Patients with Chronic Rhinosinusitis

Ko YK, Zhang YL, Wee JH, Han DH, Kim HJ, Rhee CS

Objectives. This study was conducted to determine whether patients with allergic rhinitis might be more susceptible to human rhinovirus (HRV) infection and whether the effects of infection on the elicited...
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Age Differences in Pet Sensitization by Pet Ownership

Won JY, Kwon JW, Hong SN, Lee WH

Objectives. The association between pet sensitization and pet ownership remains unclear. Therefore, we aimed to elucidate the association between pet sensitization and pet ownership by age. Methods. We retrospectively reviewed 2,883...
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The Influence of COVID-19 on Asthma and Allergic Rhinitis

Kim YH

As the coronavirus disease 2019 (COVID-19) pandemic continues, doctors face many difficulties in managing patients with respiratory allergies. As research continues, much new knowledge has emerged about the link between...
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The impact of air pollution on allergic rhinitis

Lee KI, Chung YJ, Mo JH

Recently, air pollution has become more and more severe globally and has decreased the quality of life significantly in subjects with or without allergic diseases. Air pollution more severely affects...
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Data resource profile: the allergic disease database of the Korean National Health Insurance Service

Yoo S, Kim DW, Kim YE, Park JH, Kim YY, Cho Kd, Gwon MJ, Shin JI, Lee EJ

Researchers have been interested in probing how the environmental factors associated with allergic diseases affect the use of medical services. Considering this demand, we have constructed a database, named the...
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Inverse Relationship between Adenoid Size and Asthma or Atopy in Children: A Preliminary Study

Noh Y, Choi JE, Lee KE, Chung SK, Hong SD, Kim HY

Background and Objectives One of the most common surgical procedures in children is adenoidectomy, but the causes of adenoid hypertrophy are not fully understood. Some studies have found that allergies...
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Age–period–cohort analysis of asthma, allergic rhinitis, and atopic dermatitis prevalence in Japan

Okui T

This study aims to analyze the trends in the Japanese prevalence of asthma, allergic rhinitis, and atopic dermatitis by using age–period–cohort (APC) analysis. Data regarding the prevalence of diseases from...
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The Role of Aviation Medical Examiners in the Diagnosis, Treatment and Aeromedical Assessment of Patients with Allergic Rhinitis

Kim YH

Since allergic rhinitis is a disease with a very high prevalence, it is common to find patients with allergic rhinitis among aviation workers. However, they are so afraid that the...
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Effects of Air Purifiers on Patients with Allergic Rhinitis: a Multicenter, Randomized, Double-Blind, and Placebo-Controlled Study

Park KH, Sim DW, Lee SC, Moon S, Choe E, Shin H, Kim SR, Lee JH, Park HH, Huh D, Park JW

Purpose: Exposure to particulate matter (PM) is a well-known risk factor in the triggering and exacerbation of allergic airway disease. Indoor environments, where people spend most of their time, are...
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Effect of ethnicity on the prevalence of allergic disease

Kim HS, Kim HH

Differences in the prevalence and severity of allergic diseases exist among racial and ethnic groups. However, influence of population admixing on allergic disease has not been studied. This review aimed...
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Luteolin reduces fluid hypersecretion by inhibiting TMEM16A in interleukin-4 treated Calu-3 airway epithelial cells

Kim HJ, Woo J, Nam YR, Seo Y, Namkung W, Nam JH, Kim WK

Rhinorrhea in allergic rhinitis (AR) is characterized by the secretion of electrolytes in the nasal discharge. The secretion of Cl– and HCO3 – is mainly regulated by cystic fibrosis transmembrane...
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Ten-Year trends and prevalence of asthma, allergic rhinitis, and atopic dermatitis among the Korean population, 2008–2017

Ha J, Lee SW, Yon DK

Background: Major questions remain regarding the agestratified trends of allergic diseases and asthma in Korea. Purpose: To identify the estimated recent prevalence and 10- year trends in asthma, allergic rhinitis, and...
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The Effects of Seogeum Therapy on Nasal Eosinophil, Nasal Symptoms, and Rhinitis Related Quality of Life in College Students with Allergic Rhinitis

Park Y, Kim N

Purpose: The purpose of this study was to examine the effect of Seogeum therapy on nasal eosinophil, nasal symptoms, and rhinitisrelated quality of life in college students with allergic rhinitis....
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Application of Stem Cell-Derived Extracellular Vesicles in Allergic Airway Diseases

Kim SD, Cho KS

Mesenchymal stem cells (MSCs) have been reported to be promising candidates for the treatment of allergic airway diseases. However, MSCs themselves have several problems including immune rejection, risk of aneuploidy,...
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Anti-allergic Effects of Caffeine in an Allergic Rhinitis Mouse Model

Fan YJ, Piao CH, Nguyen TV, Yu ZN, Chai OH, Song CH

Caffeine (1, 3, 7-trimethylxanthine) is one of the most widely consumed pharmacologically active products worldwide. Caffeine exhibits various pharmacological activities in central nervous, cardiovascular, and respiratory systems. Additionally, caffeine exhibited...
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Analysis on the Effects of Particular Matter Distribution on the Number of Outpatient Visits for Allergic Rhinitis

Park JH, Park YY, Lee E, Lee KS

Background: This study aims to analyze the effects of air pollutants, such as particular matter, to the number of outpatient visits for allergic rhinitis in eup, myeon, and dong administrative...
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Primary Nasal Epithelial Cells From Allergic and Non-allergic Individuals Show Comparable Barrier Function

Waltl EE, Stanek V, Mueller CA, Kiss R, Eckl-Dorna J, Valenta R, Niederberger V

Previous reports suggested that ex vivo cultured primary nasal epithelial cells from allergic patients differ from those from non-allergic individuals by genuinely reduced barrier function. By contrast, we found that...
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Strain-Specific Differences in House Dust Mite (Dermatophagoides farinae)-Induced Mouse Models of Allergic Rhinitis

Lee KI, Bae JS, Kim EH, Kim JH, Lyu L, Chung YJ, Mo JH

Objectives. Limited information is available regarding strain-related differences in mouse models of allergic rhinitis induced by Dermatophagoides farinae (Der f1). In this study, we compared differences between two mouse strains...
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