Korean J Med.
2009 Aug;77(Suppl 1):S48-S51.
A case of metronidazole induced encephalopathy in a cirrhotic patient
- Affiliations
-
- 1Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. jikim@catholic.ac.kr
- 2Department of Radiology, The Catholic University of Korea College of Medicine, Seoul, Korea.
Abstract
- Metronidazole induced encephalopathy is a rare disease caused by the antibiotic drug, metronidazole. Metronidazole is a nitroimidazole antibiotic used for anaerobic infections, Helicobacter pylori infection and spontaneous bacterial peritonitis. Metronidazole has good cellular penetration and is believed to penetrate the CSF and central nervous system. The incidence of metronidazole induced encephalopathy is unknown, though several previous studies have addressed brain changes caused by metronidazole neurotoxicity. Neurologic side effects include peripheral neuropathy, seizures, encephalopathy, dysarthria, and ataxia. We experienced a case of metronidazole induced encephalopathy, diagnosed by brain MRI in a patient with spontaneous bacterial peritonitis and performed follow-up imaging after discontinuation of metronidazole.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Metronidazole Induced Encephalopathy in a Patient with Brain Abscess
- Oculogyric Crisis Due to Metronidazole Toxic Encephalopathy
- Metronidazole-induced encephalopathy in a patient with liver cirrhosis
- A Case of Metronidazole-Induced Encephalopathy: Atypical Involvement of the Brain on MRI
- Reversible Encephalopathy Induced by Metronidazole
