Korean J Nephrol.
2011 Jul;30(4):424-428.
Acute Interstitial Nephritis during the First Course of Rifampin Administration in a Renal Transplant Patient
- Affiliations
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- 1Department of Internal Medicine, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea. gustmd1@naver.com
- 2Department of Pathology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.
Abstract
- Tuberculosis is recognized as one of the most important complications in an organ transplant recipient. Rifampin has become a standard agent in the treatment of tuberculosis. While rifampin is well tolerated in most patients, adverse effects, including serious forms of toxicity, have been reported. Some of these adverse effects include liver toxicity and various immunologic reactions such as skin rashes, eosinophilia, and interstitial nephritis. We have experienced a case of acute interstitial nephritis during the first course of standard anti-tuberculous therapy in a renal transplant patient. We should not ignore other causes of interstitial nephritis in a renal transplant patient.
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