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Effectiveness of Intravenous Isoniazid and Ethambutol Administration in Patients with Tuberculosis Meningoencephalitis and HIV Infection

Butov D, Feshchenko Y, Kuzhko M, Gumenuik M, Yurko K, Grygorova , Tkachenko , Nekrasova , Tlustova T, Kikinchuk , Peshenko A, Butova T

BACKGROUND: The aim of this study was to investigate the effectiveness of intravenous isoniazid (H) and ethambutol (E) administered in patients with new sputum positive drug-susceptible pulmonary tuberculosis (TB) with...
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Treatment of Isoniazid-Resistant Pulmonary Tuberculosis

Jhun BW, Koh WJ

Tuberculosis (TB) remains a threat to public health and is the leading cause of death globally. Isoniazid (INH) is an important first-line agent for the treatment of TB considering its...
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Rifampin-Induced Immune Hemolytic Anemia during Treatment of Pulmonary Tuberculosis in a Patient with Primary Sjogren's Syndrome

Souk JW, Kim YK, Jang GE, Jeong HS, Uh ST, Kim KU, Koo SM, Lee BY, Noh H, Shin WY, Shin JW, Jin SY

Drug-induced immune hemolytic anemia is a rare disease that occurs in 1 in 1 million individuals of the general population. Rifampin-induced immune hemolytic anemia is caused by drug-dependent antibodies and...
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Relapsed Leprosy with Multiple Ulcerative Skin Lesions: A Case Report

Jeong HH, Hong SG, Park JM, Kim JP, Heo EP, Go JW

Leprosy is a chronic infectious and granulomatous disease caused by Mycobacterium leprae. It is treated with a multidrug therapy (MDT), which is consisted of dapsone, rifampicin, and clofazimine. However, there...
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Screening and Treatment of Latent Tuberculosis Infection among Healthcare Workers at a Referral Hospital in Korea

Park SY, Lee E, Lee EJ, Kim TH, Kim YK

BACKGROUND: Healthcare workers (HCWs) have a high risk of tuberculosis (TB) infection. Since August 2017, Korea has mandated the testing of latent TB infection (LTBI) and recommended treatment from HCWs...
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Pathologic characteristics for the Rhodococcus equi infection in foals in Jeju

From 1996 to 2014, 14 foals from nine farms in Jeju were diagnosed with a Rhodococcus equi infection. Clinically, most foals showed characteristic respiratory signs, including hyperthermia and dyspnea. The...
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Report of the Korean Association of External Quality Assessment Service on Clinical Mycobacteriology (2017–2018)

Shin S, Hong SH

Rapid and correct diagnosis is essential for national tuberculosis (TB) control. A greater national concern for quality control (QC) of Mycobacterium tuberculosis (MTB) testing is required to improve the proficiency...
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Thromboembolism in Mycobacterium tuberculosis Infection: Analysis and Literature Review

Ha H, Kim KH, Park JH, Lee JK, Heo EY, Kim JS, Kim DK, Choi IS, Chung HS, Lim HJ

BACKGROUND: Tuberculosis is associated with hypercoagulation; however, there are few reports of cases thromboembolism and tuberculosis at the same time in the real world. The purpose of this study was...
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Benign Recurrent Intrahepatic Cholestasis Type 2 in Siblings with Novel ABCB11 Mutations

Sohn MJ, Woo MH, Seong MW, Park SS, Kang GH, Moon JS, Ko JS

Benign recurrent intrahepatic cholestasis (BRIC), a rare cause of cholestasis, is characterized by recurrent episodes of cholestasis without permanent liver damage. BRIC type 2 (BRIC2) is an autosomal recessive disorder...
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Early Detection and Analysis of Children with Multidrug-Resistant Tuberculosis of the Spine

Arockiaraj J, Robert M, Rose W, Amritanand R, David KS, Krishnan V

STUDY DESIGN: Retrospective case series. PURPOSE: The aim of the study is to report the clinical characteristics, early diagnosis, management, and outcome of children with multidrug-resistant (MDR) tubercular spondylodiscitis and to...
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Treatment of Mycobacterium avium Complex Pulmonary Disease

Kwon YS, Koh WJ, Daley CL

The pathogen Mycobacterium avium complex (MAC) is the most common cause of nontuberculous mycobacterial pulmonary disease worldwide. The decision to initiate long-term antibiotic treatment is difficult for the physician due...
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Evaluation of in vitro antimicrobial susceptibility of Bacillus anthracis strains isolated during anthrax outbreaks in Italy from 1984 to 2017

Manzulli V, Fasanella , Parisi A, Serrecchia L, Donatiello A, Rondinone , Caruso M, Zange S, Tscherne A, Decaro N, Pedarra C, Galante D

Anthrax, caused by Bacillus anthracis, is a non-contagious infectious disease that affects a wide range of animal species (primarily ruminants) including humans. Due to the often-fatal outcome in humans, quick...
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Anti-tuberculosis Drugs-induced Anagen Effluvium with Generalized Drug Eruption

Lim C, Park KD, Seo YJ, Lee J, Lee Y

  • KMID: 2433638
  • Korean J Dermatol.
  • 2019 Jan;57(1):15-19.
Anagen effluvium is an abrupt loss of hair in its growing phase due to an event that impairs the mitotic or metabolic activity of the hair follicle. Anagen effluvium is...
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Treatment of pulmonary tuberculosis

Yoon SW, Choi JC

Tuberculosis (TB) remains the world's leading cause of death from a single infectious disease. In addition, the incidence of TB is high in South Korea. Effective TB control requires early...
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Prevalence and Clinical Features of Drug Reactions With Eosinophilia and Systemic Symptoms Syndrome Caused by Antituberculosis Drugs: A Retrospective Cohort Study

Jung HY, Park S, Shin B, Lee JH, Lee SJ, Lee MK, Lee WY, Yong SJ, Kim SH

PURPOSE: Although there have been reported cases of drug reactions with eosinophilia and systemic symptoms (DRESS) syndrome caused by antituberculosis drugs, there has been no research to examine its prevalence....
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Diagnosis and Treatment of Latent Tuberculosis Infection: The Updated 2017 Korean Guidelines

Lee SH

A small number of viable tuberculosis bacilli can reside in an individual with latent tuberculosis infection (LTBI) without obvious clinical symptoms or abnormal chest radiographs. Diagnosis and treatment of LTBI...
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Most Reliable Time in Predicting Residual Kyphosis and Stability: Pediatric Spinal Tuberculosis

Moon MS, Kim SJ, Kim MS, Kim DS

STUDY DESIGN: A case study. PURPOSE: To assess the chronological changes of the disease-related kyphosis after chemotherapy alone, secondly to clarify the role of growth cartilage in the healed lesion on...
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Correction: Detection of Rifampicin Resistance in Mycobacterium tuberculosis by Using Middlebrook 7H9 Broth Medium with 2,3-Diphenyl-5-Thienyl-(2)-Tetrazolium Chloride

Lee SM, Kim KJ, Chang CL

The acknowledgement was missed without intention. The authors ask to add the acknowledgement ‘This work was supported by a 2-Year Research Grant of Pusan National University.’ in an appropriate section.
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Bilateral Lesions in the Posterior Limb of Internal Capsule Attributed to Combination Therapy of Isoniazid and Rifampin

Park MW, Roh J, Im S, Kim MO, Kim YS, Kang J, Kim DH, Kwon OY

Transient isoniazid-induced brain lesions have rarely been reported. The lesions were in the dentate nucleus of cerebellum and thalamus. Meanwhile, the neurotoxicity of rifampin has not been reported evidently. We...
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Detection of Rifampicin- and Isoniazid-Resistant Mycobacterium tuberculosis Using the Quantamatrix Multiplexed Assay Platform System

Wang HY, Uh Y, Kim S, Cho E, Lee JS, Lee H

BACKGROUND: The increasing prevalence of drug-resistant tuberculosis (TB) infection represents a global public health emergency. We evaluated the usefulness of a newly developed multiplexed, bead-based bioassay (Quantamatrix Multiplexed Assay Platform...
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