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Non-episodic Angioedema With Eosinophilia Successfully Treated With Reslizumab

Chu H, Youn DY, Park HS, Ye YM, Park YB, Ban GY

No abstract available.
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Evaluation of Neo-Osteogenesis in Eosinophilic Chronic Rhinosinusitis Using a Nasal Polyp Murine Model

Khalmuratova R, Lee M, Park JW, Shin HW

PURPOSE: Osteitis refers to the development of new bone formation and remodeling of bone in chronic rhinosinusitis (CRS) patients; it is typically associated with eosinophilia, nasal polyps (NPs), and recalcitrant...
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Altered T cell and monocyte subsets in prolonged immune reconstitution inflammatory syndrome related with DRESS (drug reaction with eosinophilia and systemic symptoms)

Kang SY, Kim J, Ham J, Cho SH, Kang HR, Kim HY

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a severe cutaneous adverse reaction involving various internal organs. Flare-ups after recovery from the initial presentation of DRESS are caused...
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A case of toxic epidermal necrolysis induced by cytomegalovirus infection followed by DRESS (drug reaction with eosinophilia and systemic symptoms)

Sim DW, Son S, Yu J, Koh YI

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome and toxic epidermal necrolysis (TEN) are severe cutaneous adverse reactions. Although viral reactivation is associated with DRESS syndrome, its role in...
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Chronic Eosinophilic Pneumonia Masquerading As Bronchogenic Malignancy

Park C, Hwang KE

No abstract available.
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Nasal eosinophilia and eosinophil peroxidase in children and adolescents with rhinitis

Choi Y, Jeon H, Yang EA, Yoon JS, Kim HH

BACKGROUND: Researchers have shown that eosinophil peroxidase (EPO) is a relatively accurate marker of eosinophilia and eosinophil activity. However, its use as a marker of eosinophilic inflammation in nasal secretions...
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Eosinophilic Enteritis Presenting as Massive Ascites after Influenza A Virus Infection in a Young Female

Kim MJ, Oh MJ

Eosinophilic gastrointestinal disorder (EGID) is an uncommon disease that is accompanied by intestinal eosinophil infiltration without a secondary cause of eosinophilia. Eosinophilic enteritis is a secondary portion of EGID that...
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Cutaneous adverse drug reactions in patients with peripheral blood eosinophilia during antituberculosis treatment

Kim TO, Shin HJ, Kim YI, Lim SC, Koh YI, Kwon YS

BACKGROUND/AIMS: Peripheral eosinophilia during tuberculosis (TB) treatment is common, but has not been fully evaluated. The aim of this study was to determine the prevalence and clinical significance of peripheral...
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Immunological Characteristics in Refractory Chronic Rhinosinusitis with Nasal Polyps Undergoing Revision Surgeries

Ryu G, Kim DK, Dhong HJ, Eun KM, Lee KE, Kong IG, Kim H, Chung SK, Kim DY, Rhee CS, Cho SH, Hong SD, Kim DW

PURPOSE: Despite medical and surgical treatments, some cases of nasal polyps (NP) exhibit recidivism. However, the endotype of refractory chronic rhinosinusitis with NP (CRSwNP) remains unclear. Therefore, the objective of...
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Clinical and Endoscopic Features of Colonic Anisakiasis in Korea

Joo SK, Kim JW, Kim BG, Kim W, Lee JK, Lee KL

To analyze the clinical and endoscopic features of colonic anisakiasis. A retrospective chart review of 20 patients with colonic anisakiasis, who were diagnosed by colonoscopy at 8 hospitals between January...
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Significance of Differential Characteristics in Infantile Kawasaki Disease

Kwak JH, Lee J, Ha KS

BACKGROUND AND OBJECTIVES: Immunological variability in Kawasaki disease (KD) shows age-specific differences; however, specific differences in laboratory values have not been compared between infants and non-infants with KD. We compared...
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Eosinophilic Granulomatosis with Polyangiitis: Experiences in Korean Patients

Choi CB, Park YB, Lee SW

Eosinophilic granulomatosis with polyangiitis (EGPA) is one form of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. Identical to what has been called Churg-Strauss syndrome, EGPA exhibits both allergic and vasculitis features. EGPA...
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Etiologies and differential markers of eosinophilia-associated diseases in the Allergy Department of a single university hospital

Yu JE, Sim DW, Koh YI

PURPOSE: We aimed to analyze the frequency of eosinophilia-associated diseases and to search for possible markers that may be useful for their differential diagnosis. METHODS: We retrospectively reviewed the medical records...
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Concurrent bilateral juvenile temporal arteritis and hypereosinophilic syndrome: a case report and review of the literature

Shim JS, Oh JH, Chung SJ, Kim BK, Chang YS, Kim SH

Most of temporal arteritis occurs in the older patient over 50 years old, and the histopathologic finding shows a granulomatous inflammation, so this called giant cell arteritis. However, the young...
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Human leukocyte antigen-associated severe cutaneous adverse drug reactions: from bedside to bench and beyond

Nguyen DV, Vidal C, Chu HC, van Nunen

Despite their being uncommon, severe cutaneous adverse drug reactions (SCARs) result in a very great burden of disease. These reactions not only carry with them a high mortality (10%–50%) and...
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Classification of Antineutrophil Cytoplasmic Antibody-associated Vasculitis

Lee SW, Park YB

Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a group of systemic vasculitides, that are characterized by inflammation in the small vessels, ranging from capillaries to arterioles or venules. AAV is...
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Three Fibrotic Conditions Treated with 5% Topical Imiquimod Cream as an Antifibrotic Agent

Cho YR, Kim HJ, Seo JW, Kim TH, Kim KH

  • KMID: 2451589
  • Korean J Dermatol.
  • 2019 Jun;57(5):265-269.
Imiquimod, a toll-like receptor agonist, is a topical immunomodulator that induces the production of several cytokines including interferon-alpha, which shows antifibrotic properties. We hypothesized that the antifibrotic effect of imiquimod...
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Revisiting the Clinical Scoring System for the Prognosis of Chronic Rhinosinusitis with Nasal Polyps

Kim JY, Han YE, Seo Y, Choe G, Kim MK, Huh G, Cho D, Yang SK, Kang SH, Kim DW

PURPOSE: To evaluate the Japanese Epidemiological Survey of Refractory Eosinophilic Chronic Rhinosinusitis (JESREC) classification, a clinical scoring system, for predicting disease control status in chronic rhinosinusitis with nasal polyps (CRSwNP)...
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Which Factors Associated With Activated Eosinophils Contribute to the Pathogenesis of Aspirin-Exacerbated Respiratory Disease?

Choi Y, Lee Y, Park HS

Eosinophils have long been recognized as a central effector cell in the lungs of asthmatic patients. They contribute to airway inflammation and remodeling through releasing several molecules such as cytokines,...
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Recurrent Eosinophilic Pneumonia Associated with Mesalazine Suppository in a Patient with Ulcerative Colitis

Park M, Lee J, Kang SB, Park Y

Mesalazine suppositories are widely used to treat ulcerative colitis and have a guaranteed safety profile, but although rare, they can cause pulmonary toxicity. A 35-year-old woman with ulcerative colitis was...
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