Korean J Anesthesiol.
1989 Aug;22(4):482-487. 10.4097/kjae.1989.22.4.482.
The Cardiovascular Effects of Vecuronium during Anesthesia with Isoflurane
- Affiliations
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- 1Department of Anesthesiology, College of Medicine, Pusan National University, Pusan, Korea.
- KMID: 2239417
- DOI: http://doi.org/10.4097/kjae.1989.22.4.482
Abstract
- To investigate the cardiovascular effects of vecuronium during isoflurane anesthesia, I compared with effects of pancuronium. Eight mongrel dogs were anesthetized with intravenous thiopental sodium and maintained with oxygen (41/min)-isoflurane (1 MAC). Cardiovascular parameters were determined and recorded 1 minute before and 5, 10, 20, 30 minutes after administration of 3 times the ED, dose of pancuronium and vecuronium respectively. Only one neuromuscular relaxant was studied with each anesthetic administration. The results are as follows; 1) Pancuronium increased heart rate, mean arterial blood pressure, cardiac output. 2) Vecuronium caused no significant cardiovascular chanaes.
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