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Comparison of the effects of isoflurane versus propofol-remifentanil anesthesia on oxygen delivery during thoracoscopic lung lobectomy with one-lung ventilation in dogs

Park J, Lee HB, Jeong SM

This study compared effects of isoflurane inhalation (ISO) and propofol-remifentanil combined total intravenous anesthesia (TIVA) on oxygenation during thoracoscopic lung lobectomy with 30-min one-lung ventilation (1LV). Thoracoscopic right middle lung...
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Changes in Serum Concentrations of Insulin-like Growth Factor Binding Protein-3 after General Anesthesia Using Propofol or Isoflurane

Woo JH, Kim JH, Baik HJ, Lee M, Kim YJ

OBJECTIVES: The insulin-like growth factor binding proteins (IGFBP) regulate the bioavailability and bioactivity of insulin-like growth factor. We aimed to evaluate whether the IGFBP-3 level undergo major changes during perioperative...
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Isoflurane Preconditioning Induces Neuroprotection by Up-Regulation of TREK1 in a Rat Model of Spinal Cord Ischemic Injury

Wang K, Kong X

This study aimed to explore the neuroprotection and mechanism of isoflurane on rats with spinal cord ischemic injury. Total 40 adult male Sprague-Dawley rats were divided into the four groups...
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Pupil Size in Relation to Cortical States during Isoflurane Anesthesia

Kum JE, Han HB, Choi JH

In neuronal recording studies on anesthetized animals, reliable measures for the transitional moment of consciousness are frequently required. Previous findings suggest that pupil fluctuations reflect the neuronal states during quiet...
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Cardiopulmonary effects of thiopental versus propofol as an induction agent prior to isoflurane anesthesia in chair trained rhesus macaques (Macaca mulatta)

Choi YJ, Park HJ, Kim HH, Lee YJ, Jung KC, Park SH, Lee JI

The purpose of this study was to evaluate the effects of thiopental versus propofol on cardiopulmonary functions, when used as an induction agent prior to isoflurane anesthesia in rhesus monkeys....
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Effect of isoflurane post-treatment on tPA-exaggerated brain injury in a rat ischemic stroke model

Kim EJ, Kim SY, Lee JH, Kim JM, Kim JS, Byun JI, Koo BN

BACKGROUND: Intravenous tissue-type plasminogen activator (tPA) is recognized as the standard treatment for ischemic stroke. However, its narrow therapeutic window and association with an increased risk of intracranial hemorrhage have...
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Combination of Nitrous Oxide with Isoflurane or Scopolamine for Treatment-resistant Major Depression

Yang C, Hashimoto

No abstract available.
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The Effects of Propofol and Isoflurane on Blood Glucose during Abdominal Hysterectomy in Diabetic Patients

Behdad S, Mortazavizadeh A, Ayatollahi V, Khadiv Z, Khalilzadeh S

BACKGROUND: Acute hyperglycemia in the perioperative period is associated with significantly increased complications. In few human studies the effects of propofol and inhalational anesthetic on the glucose metabolism were compared....
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Isoflurane Anesthesia Therapy for Nonconvulsive Status Epilepticus Continuing after the Control of Convulsive Status Epilepticus: A case report

Lee C, Son Y

Nonconvulsive status epilepticus (NCSE) is defined as continuous or nearly continous electrographic seizure activity lasting at least 30 minutes without clinical signs of convulsive activity. The presence of NCSE after...
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The Effect of Nitrous Oxide on Cerebral Entropy during Isoflurane Inhalational Anesthesia

Park KS, Park JC, Moon BK, Lee SY, Kim JS, No HJ

BACKGROUND: The bispectral index has limitations in describing the exact depth of anesthesia during nitrous oxide inhalation. This study examined the effect of nitrous oxide on the cerebral entropy measured...
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Effect of Administration Method of Isoflurane on Bispectral Index Values in the Early Period of Cesarean Section: A Comparison of End-Tidal or Vaporizer Concentration using Overpressure

Lee HJ, Kim JB, Choi HJ

BACKGROUND: Patients undergoing a cesarean section under general anesthesia are at risk of intraoperative awareness due to the use of low concentration of volatile anesthetics used. This study...
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The Effect of Halothane and Isoflurane on KCNK2 Transfected HEK-293 Cells

Shin WJ, Kim HJ, Shim JH, Jeon WJ, Cho SY, Yeom JH, Kim KH, Kim KS

BACKGROUND: According to the report that KCNK activity in transfected COS-7 and HEK-293 cells was modulated by volatile anesthetics and activation of KCNK channels by neuroprotectants, the importance of KCNK2...
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Protective Effect of Isoflurane on Noise-induced Hearing Loss in Mice

Ku SW, Shin JW, Lee JY, Kim JU, Lee SK, Chung JW, Lee EH

BACKGROUND: It is well known that the loud noise exposure can lead to noise-induced hearing loss (NIHL). Drilling during mastoid surgery may result in NIHL. The noise level produced by...
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The Comparison of Recovery Characteristics Following Anesthesia with Propofol, Sevoflurane or Isoflurane in Adults Undergoing Outpatient Surgery

Shin JM, Park JS, Park BS, Lee YJ

BACKGROUND:Outpatient surgery has recently grown in popularity. This trend has affected the practice of anesthesia and has also led to an increasing interest in the development and use of short-acting...
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The Comparative Effect of Fentanyl and Isoflurane on Splanchnic Perfusion during Cardiac Surgery

Hong SJ

BACKGROUND: Splanchnic perfusion derangement commonly occurs during cardiac surgery, while splanchnic ischemia is known to increase morbidity in surgical and critically ill patients. We hypothesized that anesthetic agents may have...
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The Effect of Enflurane, Isoflurane and Propofol on Hepatic Function in Tympanomastoidectomy

Kim SH, Shin OY, Kim KS, Kang HJ

BACKGROUND: Isoflurane and propofol are known to have a low potential for hepatotoxicity. However, no study has compared the effects on hepatic function after of enflurane, isoflurane or propofol in...
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Spinal Antinociceptive Mechanism of Isoflurane and Enflurane via the GABAA Receptor in Rats

Choi DK, Kim YK, Ham KD, Hwang JH

Background: Several studies have suggested that the spinal cord may be an important site of anesthetic action and have established that general anesthetics potentiate the effects of GABA at the...
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Effects of Desflurane and Isoflurane on Arterial Oxygenation and Hemodynamics during One-lung Ventilation

Shin JW, Ham KD, Baek CW, Park SH, Choi IC, Lee C

BACKGROUND: Potent inhalational agents are widely used for thoracic anesthesia. They have several desirable properties, including ease of administration, rapid onset and offset, and bronchodilation. One potential drawback is their...
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The Effect of Trifluoroacetic Acid, a Metabolite of Isoflurane on the ATP-sensitive Potassium Channel in Rabbit Ventricular Myocytes

Lee DJ, Kim SJ, Ha KH, Kim MC, Cho KH

BACKGROUND: Activation of ATP-sensitive K+ channels (KATP channels) in the cardiac muscle produces cardioprotective effects during myocardial ischemia. Previous experimental evidence indicates that volatile anesthetics exert beneficial actions in ischemic...
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Effects of Intrathecal Calcium Channel Blockers on the MAC of Isoflurane in Rats

Yoon MH, Choi JI, Jeong SW

BACKGROUND: Much evidence suggests that the spinal cord may be an important anesthetic action site. Volatile anesthetics have been shown to inhibit neurotransmitter release by inhibition of intracellular calcium entry....
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