Korean J Anesthesiol.  2002 May;42(5):581-586. 10.4097/kjae.2002.42.5.581.

Comparison of Isoflurane, Sevoflurane and Desflurane Anesthesia on Potentiation of Muscle Relaxation, Recovery Profile and Cost according to Consumed Amount

Affiliations
  • 1Department of Anesthesiology, College of Medicine, The Catholic University of Korea, Seoul, Korea. vincnt@chollian.net

Abstract

BACKGROUND: We evaluated the potentiating effect of anesthetics to vecuronium, and recovery profiles, and cost according to the consumption amounts, and usefulness of newly developed anesthetic agents for ambulatory anesthesia.
METHODS
Seventy-five patients undergoing a major gynecological surgery were randomly divided into three groups. Group 1 received isoflurane, group 2 received sevoflurane, and group 3 received desflurane. Clinical duration, recovery index, recovery time in each group, and consumption of volatile anesthetics by weighing the vaporizes were measured.
RESULTS
Emergence from anesthesia was more rapid in the group 2 and 3, and there was no significant difference in potentiating effect of anesthetics to a neuromuscular blocker among the three groups. Costs according to the comsumption amount were significantly higher in the group 2 and 3.
CONCLUSIONS
Sevoflurane and desflurane clinically represent a more efficient alternative to isoflurane in ambulatory anesthesia because of their rapid emergence without side effects.

Keyword

Desflurane; isoflurane; recovery; sevoflurane; vecuronium

MeSH Terms

Anesthesia*
Anesthetics
Female
Gynecologic Surgical Procedures
Humans
Isoflurane*
Muscle Relaxation*
Neuromuscular Blockade
Vecuronium Bromide
Anesthetics
Isoflurane
Vecuronium Bromide
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