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Multi-Layer Onlay Graft Using Hydroxyapatite Cement Placement without Cerebrospinal Fluid Diversion for Endoscopic Skull Base Reconstruction

Kim YH, Kang H, Dho YS, Hwang K, Joo JD, Kim YH

Objective : The skull base reconstruction step, which prevents cerebrospinal fluid (CSF) leakage, is one of the most challenging steps in endoscopic skull base surgery (ESS). The purpose of this...
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Growth Pattern and Prognostic Factors of Untreated Nonfunctioning Pituitary Adenomas

Hwang K, Kwon T, Park J, Joo JD, Han JH, Oh CW, Kim CY

OBJECTIVE: Pituitary adenomas (PAs) are often detected as incidental findings. However, the natural history remains unclear. The objective of this study was to evaluate the natural history and growth pattern...
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Amitriptyline inhibits the MAPK/ERK and CREB pathways and proinflammatory cytokines through A3AR activation in rat neuropathic pain models

Kim Y, Kwon SY, Jung HS, Park YJ, Kim YS, In JH, Choi JW, Kim JA, Joo JD

BACKGROUND: The pain-relief properties of tricyclic antidepressants can be attributed to several actions. Recent observations suggest that adenosine is involved in the antinociceptive effect of amitriptyline. The A3 adenosine receptor...
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Orbital wall restoring surgery with resorbable mesh plate

Joo JD, Kang DH, Kim HS

BACKGROUND: Orbital resorbable mesh plates are adequate to use for isolated floor and medial wall fractures with an intact bony buttress, but are not recommended to use for large orbital...
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Optic Nerve Sheath Meningioma: Preliminary Analysis of the Role of Radiation Therapy

Jin J, Joo JD, Han JH, Yang HK, Hwang JM, Kim YJ, Kim IA, Kim CY

BACKGROUND: The purpose of this study was to evaluate the treatment outcome of our optic nerve sheath meningioma (ONSM) case series in terms of preventing tumor growth and preserving vision...
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Outcomes in 20 Gynecologic Cancer Patient with Brain Metastasis: A Single Institution Retrospective Study

Kim SB, Hwang K, Joo JD, Han JH, Kim YB, Kim CY

BACKGROUND: The incidence of brain metastasis (BM) in gynecologic cancers has risen recently, due to prolonged survival times and an early diagnosis. We analyzed treatment outcomes of patients with BM...
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The Role of Adjuvant Treatment in Patients with High-Grade Meningioma

Cho M, Joo JD, Kim IA, Han JH, Oh CW, Kim CY

OBJECTIVE: To investigate the efficacy of adjuvant treatment in patients with high-grade meningioma. METHODS: A retrospective analysis was performed for patients with high-grade meningioma, World Health Organization grade 2 or 3,...
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Cranial Defect Overlying a Ventriculoperitoneal Shunt: Pressure Gradient Leading to Free Flap Deterioration?

Joo JD, Jang JU, Kim H, Yoon ES, Kang DH

We report a case of free flap deterioration which may have been induced by pressure gradient resulting from cranial defect overlying a ventriculoperitoneal shunt (VP shunt). The patient, male and...
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The Effects of Remifentanil on Expression of High Mobility Group Box 1 in Septic Rats

Seo KH, Choi JW, Jung HS, Yoo H, Joo JD

High mobility group box 1 (HMGB1) is a pivotal mediator of sepsis progression. Remifentanil, an opioid agonist, has demonstrated anti-inflammatory effects in septic mice. However, it is not yet known...
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Health-Related Quality of Life in Brain Tumor Patients Treated with Surgery: Preliminary Result of a Single Institution

Kim CW, Joo JD, Kim YH, Han JH, Kim CY

BACKGROUND: Alongside the extent of removal and patients’ survival in the management of brain tumors, health-related quality of life (HRQOL) has become an important consideration. The purpose of this study...
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Spontaneous Involution of Rathke’s Cleft Cysts without Visual Symptoms

Kim CW, Hwang K, Joo JD, Kim YH, Han JH, Kim CY

BACKGROUND: There have been various reports in the literature regarding the conservative management of pituitary apoplexy, pituitary incidentalomas and Rathke cleft cysts (RCCs). However, to the best of our knowledge,...
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Comparison of an Intraoperative Infusion of Dexmedetomidine, Fentanyl, and Remifentanil on Perioperative Hemodynamics, Sedation Quality, and Postoperative Pain Control

Choi JW, Joo JD, Kim DW, In JH, Kwon SY, Seo K, Han D, Cheon GY, Jung HS

We aimed to compare fentanyl, remifentanil and dexmedetomidine with respect to hemodynamic stability, postoperative pain control and achievement of sedation at the postanesthetic care unit (PACU). In this randomized double-blind...
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Hypothalamic Extraventricular Neurocytoma (EVN) in a Pediatric Patient: A Case of EVN Treated with Subtotal Removal Followed by Adjuvant Radiotherapy

Cho M, Joo JD, Kim BH, Choe G, Kim CY

Extra ventricular neurocytoma (EVN) is a rare brain tumor with histologic features similar with a central neurocytoma, but located outside of the ventricular system. In this study, we present an...
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Effects of Dexmedetomidine Infusion on the Recovery Profiles of Patients Undergoing Transurethral Resection

Kwon SY, Joo JD, Cheon GY, Oh HS, In JH

Transurethral resection has been the gold standard in the operative management of benign prostatic hyperplasia and bladder tumor; however, it is associated with several complications that may cause patient discomfort....
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Validation of the Effectiveness and Safety of Temozolomide during and after Radiotherapy for Newly Diagnosed Glioblastomas: 10-year Experience of a Single Institution

Joo JD, Kim H, Kim YH, Han JH, Kim CY

This study was performed to validate the effectiveness and safety of concurrent chemoradiotherapy and adjuvant therapy with temozolomide for newly diagnosed glioblastoma multiforme as a standard treatment protocol. Between 2004...
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Aminophylline Partially Prevents the Decrease of Body Temperature during Laparoscopic Abdominal Surgery

Kim DW, Lee JA, Jung HS, Joo JD, In JH, Jeon YS, Chun GY, Choi JW

Aminophylline can elicit thermogenesis in rats or increase metabolic rate during cold stress in lambs. We tested the hypothesis that aminophylline would reduce the change in core body temperature during...
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Effect of milrinone on the inflammatory response and NF-kB activation in renal ischemia-reperfusion injury in mice

Jung HS, Joo JD, Kim DW, In JH, Roh M, Jeong JT, Noh SJ, Choi JW

BACKGROUND: Milrinone increases intracellular adenosine 3',5'-cyclic monophosphate concentration and enhances vascular relaxation. Nuclear factor-kappa B (NF-kB) plays a key role in inflammatory responses during ischemia-reperfusion (I/R) injury. We aimed to...
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Ketamine reduces the induced spinal p38 MAPK and pro-inflammatory cytokines in a neuropathic rats

Kwon SY, Yeom JH, Joo JD

BACKGROUND: Neuropathic rats created by spinal nerve ligation are known to show higher levels of p38, c-Jun NH2-terminal kinase, and extracellular signal-regulated kinase p44/42 (ERK 1/2) of the mitogen-activated protein...
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Sympathetically mediated upper back pain after coronary artery bypass graft surgery

Kwon SY, Joo JD, Kim JH, Jeong JT

No abstract available.
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The comparison of sedation quality, side effect and recovery profiles on different dosage of remifentanil patient-controlled sedation during breast biopsy surgery

Joo JD, In JH, Kim DW, Jung HS, Kang JH, Yeom JH, Choi JW

BACKGROUND: The patient-controlled sedation (PCS) allows for rapid individualized titration of sedative drugs. Propofol has been the most widely used IV adjuvant, during the monitored anesthesia care (MAC). This study...
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