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Authors investigated the effects of intravenous anesthetics(pentothal, thalamonal, valium) on visual evoked potentials with 8 cats. The following results were obtained: 1) Visual evoked potentials was not obtainable with pattern...
Peripheral nerve blocks are commonly used for surgical anesthesia, postoperative analgesia, and to reduce opioid requirements. Although these blocks have traditionally been carried out using local anesthetics, single-injection techniques can...
Voltage-gated sodium channels are large glycoproteins that permit selective sodium ion conduction in excitable cells such as neurons. They generate upstroke of action potential and transmit depolarizing impulses through the...
General anesthetics produce a widespread neurodepression in the central nervous system by enhancing inhibitory neurotransmission and reducing excitatory neurotransmission. However, the action mechanisms of general anesthetics are not completely understood....
Genetic and/or environmental factors lead to large inter-individual variability in the efficacy and the side effects of drugs. Pharmacogenetics is the study of genetically determined differences in drug response. It...
Lidocaine is considered a safe and effective local anesthetic in anesthesiology and is the standard to which new amide anesthetics are compared. As it an amide derivative, and the frequency...