J Korean Acad Conserv Dent.  2003 Nov;28(6):475-484. 10.5395/JKACD.2003.28.6.475.

The influence of epinephrine concentration in local anesthetics on pulpal and gingival blood flows

• Lee JS
• Kim SK

• KMID: 2175622
• DOI: http://doi.org/10.5395/JKACD.2003.28.6.475

Abstract

No abstract available.

Keyword

Epinephrine; Local anesthetics; Pulpal blood flow; Gingival blood flow; Laser Doppler flowmeter

MeSH Terms

Anesthetics, Local*
Epinephrine*
Anesthetics, Local
Epinephrine

Figure

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  Fig. 1 Flow chart recording of the changes in pulpal blood flow and gingival blood flow following injection of 2% lidocaine with 1:100,000 epinephrine. The arrows show the time of the injection (Inj).

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  Fig. 2 Flow chart recording of the changes in pulpal blood flow and gingival blood flow following injection of 2% lidocaine with 1:50,000 epinephrine. The arrows show the time of the injection (Inj).

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  Fig. 3 Graph of the changes in pulpal blood flow (PBF), gingival blood flow (GBF), and electric pulp testing (EPT) values following an injection of 2% lidocaine with 1:100,000 epinephrine.

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  Fig. 4 Graph of the changes in pulpal blood flow (PBF), gingival blood flow (GBF), and electric pulp testing (EPT) values following an injection of 2% lidocaine with 1:50,000 epinephrine.

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  Fig. 5 Effects of 2% lidocaine with 1:100,000 and 1:50,000 epinephrine on pulpal and gingival blood flows. Data are shown as percentage blood flows from the baseline values, and Mean +/- SEM. n=10. Infiltrative injection (0.9 ml) in the buccal mucosa significantly reduced both pulpal and gingival blood flows (p<0.05). Reduction of pulpal blood flow was in a dose-dependent pattern (p<0.05).

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  Fig. 6 Effects of 2% lidocaine with 1:100,000 and 1:50,000 epinephrine on the induction time to the minimum level of pulpal (PBF) and gingival blood flows (GBF), and time to complete loss of sensitivity to electric pulp test (EPT) after injection. Data are shown as time in min after injection, and Mean +/- SEM. n=10. After buccal injection of 2% lidocaine with 1:100,000 epinephrine, complete loss of sensitivity to EPT was preceded by the maximum reduction of PBF and followed by the maximum reduction of GBF.

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  Fig. 7 An example of changes in pulpal blood flow (PBF), gingival blood flow (GBF), and electric pulp testing (EPT) values following injection of 2% lidocaine with 1:50,000 epinephrine. Note the decreased PBF was recovered and increased above the baseline level at about 45 min after injection.

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