- Comparative Evaluation of Pregabalin and Clonidine as Preemptive Analgesics for the Attenuation of Postoperative Pain Following Thoracolumbar Spine Surgery
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Bala R, Kaur J, Sharma J, Singh R
- KMID: 2467428
- Asian Spine J.
- 2019 Dec;13(6):967-975.
- doi: 10.31616/asj.2019.0031
STUDY DESIGN: Prospective, randomized, double blind, placebo-controlled study. PURPOSE: To compare clonidine and pregabalin with placebo for the attenuation of postoperative pain after thoracolumbar spinal surgery and instrumentation OVERVIEW OF LITERATURE: Spine... -
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- Efficient Production of Murine Uterine Damage Model
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Kim YY, Choi BB, Lim JW, Kim YJ, Kim SY, Ku SY
- KMID: 2449243
- Tissue Eng Regen Med.
- 2019 Apr;16(2):119-129.
- doi: 10.1007/s13770-018-0149-3
BACKGROUND: Thin or damaged endometrium causes uterine factor-derived infertility resulting in a failure of embryonic implantation. Regeneration of endometrium is a major issue in gynecology and reproductive medicine. Various types of cells... -
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- Comparison of the effects of isoflurane versus propofol-remifentanil anesthesia on oxygen delivery during thoracoscopic lung lobectomy with one-lung ventilation in dogs
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Park J, Lee HB, Jeong SM
- KMID: 2412133
- J Vet Sci.
- 2018 May;19(3):426-433.
- doi: 10.4142/jvs.2018.19.3.426
This study compared effects of isoflurane inhalation (ISO) and propofol-remifentanil combined total intravenous anesthesia (TIVA) on oxygenation during thoracoscopic lung lobectomy with 30-min one-lung ventilation (1LV). Thoracoscopic right middle lung... -
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- Changes in Serum Concentrations of Insulin-like Growth Factor Binding Protein-3 after General Anesthesia Using Propofol or Isoflurane
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Woo JH, Kim JH, Baik HJ, Lee M, Kim YJ
- KMID: 2403017
- Ewha Med J.
- 2018 Jan;41(1):8-12.
- doi: 10.12771/emj.2018.41.1.8
OBJECTIVES: The insulin-like growth factor binding proteins (IGFBP) regulate the bioavailability and bioactivity of insulin-like growth factor. We aimed to evaluate whether the IGFBP-3 level undergo major changes during perioperative... -
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- Isoflurane's Effect on Intraoperative Systolic Left Ventricular Performance in Cardiac Valve Surgery Patients
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Kim JD, Son I, Kwon WK, Sung TY, Sidik H, Kim K, Kang H, Bang J, Yeo GE, Lee DK, Kim TY
- KMID: 2400646
- J Korean Med Sci.
- 2018 Jan;33(4):e28.
- doi: 10.3346/jkms.2018.33.e28
BACKGROUND: Isoflurane, a common anesthetic for cardiac surgery, reduced myocardial contractility in many experimental studies, few studies have determined isoflurane's direct impact on the left ventricular (LV) contractile function during... -
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- A prospective randomized controlled double-blind trial to assess the effects of dexmedetomidine during cleft palate surgery
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Surana P, Parikh DA, Patkar GA, Tendolkar
- KMID: 2395673
- Korean J Anesthesiol.
- 2017 Dec;70(6):633-641.
- doi: 10.4097/kjae.2017.70.6.633
BACKGROUND: We investigated whether the intraoperative administration of dexmedetomidine would attenuate the profound sympathoadrenal response associated with cleft palate (CP) surgery. METHODS: Sixty children aged 6 months to 12 years undergoing... -
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- Genistein attenuates isoflurane-induced neurotoxicity and improves impaired spatial learning and memory by regulating cAMP/CREB and BDNF-TrkB-PI3K/Akt signaling
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Jiang T, Wang XQ, Ding C, Du XL
- KMID: 2395252
- Korean J Physiol Pharmacol.
- 2017 Nov;21(6):579-589.
- doi: 10.4196/kjpp.2017.21.6.579
Anesthetics are used extensively in surgeries and related procedures to prevent pain. However, there is some concern regarding neuronal degeneration and cognitive deficits arising from regular anesthetic exposure. Recent studies... -
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- The yellow discoloration of desflurane
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Kim DJ, Jung KT
- KMID: 2377427
- Korean J Anesthesiol.
- 2017 Apr;70(2):224-225.
- doi: 10.4097/kjae.2017.70.2.224
No abstract available. -
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- Dexmedetomidine infusion as an anesthetic adjuvant to general anesthesia for appropriate surgical field visibility during modified radical mastectomy with i-gel®: a randomized control study
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Gupta K, Rastogi B, Gupta PK, Singh I, Singh VP, Jain M
- KMID: 2360471
- Korean J Anesthesiol.
- 2016 Dec;69(6):573-578.
- doi: 10.4097/kjae.2016.69.6.573
BACKGROUND: Modified radical mastectomy is associated with appreciable blood loss, while endotracheal intubation leads to elevated hemodynamic responses. The present study aimed to evaluate the clinical efficacy of dexmedetomidine infusion... -
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- Comprehensive Echocardiographic Assessment of the Right Ventricle in Murine Models
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Kohut A, Patel N, Singh H
- KMID: 2353101
- J Cardiovasc Ultrasound.
- 2016 Sep;24(3):229-238.
- doi: 10.4250/jcu.2016.24.3.229
BACKGROUND: Non-invasive high-resolution echocardiography to evaluate cardiovascular function of small animals is increasingly being used due to availability of genetically engineered murine models. Even though guidelines and standard values for... -
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- Isoflurane Preconditioning Induces Neuroprotection by Up-Regulation of TREK1 in a Rat Model of Spinal Cord Ischemic Injury
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Wang K, Kong X
- KMID: 2351673
- Biomol Ther.
- 2016 Sep;24(5):495-500.
- doi: 10.4062/biomolther.2015.206
This study aimed to explore the neuroprotection and mechanism of isoflurane on rats with spinal cord ischemic injury. Total 40 adult male Sprague-Dawley rats were divided into the four groups... -
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- Pupil Size in Relation to Cortical States during Isoflurane Anesthesia
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Kum JE, Han HB, Choi JH
- KMID: 2352878
- Exp Neurobiol.
- 2016 Apr;25(2):86-92.
- doi: 10.5607/en.2016.25.2.86
In neuronal recording studies on anesthetized animals, reliable measures for the transitional moment of consciousness are frequently required. Previous findings suggest that pupil fluctuations reflect the neuronal states during quiet... -
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- Cardiopulmonary effects of thiopental versus propofol as an induction agent prior to isoflurane anesthesia in chair trained rhesus macaques (Macaca mulatta)
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Choi YJ, Park HJ, Kim HH, Lee YJ, Jung KC, Park SH, Lee JI
- KMID: 2312149
- Lab Anim Res.
- 2016 Mar;32(1):8-15.
- doi: 10.5625/lar.2016.32.1.8
The purpose of this study was to evaluate the effects of thiopental versus propofol on cardiopulmonary functions, when used as an induction agent prior to isoflurane anesthesia in rhesus monkeys.... -
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- Effect of Propofol and Desflurane on Immune Cell Populations in Breast Cancer Patients: A Randomized Trial
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Woo JH, Baik HJ, Kim CH, Chung RK, Kim DY, Lee GY, Chun EH
- KMID: 2344186
- J Korean Med Sci.
- 2015 Oct;30(10):1503-1508.
- doi: 10.3346/jkms.2015.30.10.1503
Several factors can affect the perioperative immune function. We evaluated the effect of propofol and desflurane anesthesia on the surgery-induced immune perturbation in patients undergoing breast cancer surgery. The patients... -
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- Olanzapine Attenuates Mechanical Allodynia in a Rat Model of Partial Sciatic Nerve Ligation
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Fukuda T, Yamashita , Hisano S, Tanaka M
- KMID: 2149462
- Korean J Pain.
- 2015 Jul;28(3):185-192.
- doi: 10.3344/kjp.2015.28.3.185
BACKGROUND: Neuropathic pain is a global clinical problem; nevertheless, nerve injury treatment methods remain limited. Olanzapine has antinociceptive and anti-nueropathic properties; however, its preventive effects have not been assessed in... -
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- Effect of isoflurane post-treatment on tPA-exaggerated brain injury in a rat ischemic stroke model
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Kim EJ, Kim SY, Lee JH, Kim JM, Kim JS, Byun JI, Koo BN
- KMID: 2148694
- Korean J Anesthesiol.
- 2015 Jun;68(3):281-286.
- doi: 10.4097/kjae.2015.68.3.281
BACKGROUND: Intravenous tissue-type plasminogen activator (tPA) is recognized as the standard treatment for ischemic stroke. However, its narrow therapeutic window and association with an increased risk of intracranial hemorrhage have... -
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- Botulinum Toxin Type A Attenuates Activation of Glial Cells in Rat Medullary Dorsal Horn with CFA-induced Inflammatory Pain
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Kim MJ, Cho JH, Kim HJ, Yang KY, Ju JS, Lee MK, Park MK, Ahn DK
- KMID: 1827455
- Int J Oral Biol.
- 2015 Jun;40(2):71-77.
- doi: 10.11620/IJOB.2015.40.2.071
The activation of glial cells in the spinal cord has been contribute to the initiation and maintenance of pain facilitation induced by peripheral inflammation and nerve injury. The present study... -
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- Combination of Nitrous Oxide with Isoflurane or Scopolamine for Treatment-resistant Major Depression
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Yang C, Hashimoto
- KMID: 2171074
- Clin Psychopharmacol Neurosci.
- 2015 Apr;13(1):118-120.
- doi: 10.9758/cpn.2015.13.1.118
No abstract available. -
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- The effect of lidocaine on apoptotic neurodegeneration in the developing mouse brain
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Lee JH, Park YH, Song HG, Park HP, Kim HS, Kim CS, Kim JT
- KMID: 2039530
- Korean J Anesthesiol.
- 2014 Nov;67(5):334-341.
- doi: 10.4097/kjae.2014.67.5.334
BACKGROUND: General anesthetics induce neuronal apoptosis in the immature brain. Regional anesthesia using local anesthetics can be an alternative to general anesthesia. Therefore, this study investigated the possible effect of... -
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- Incidence and Risk Factors of Postoperative Nausea and Vomiting in Patients with Fentanyl-Based Intravenous Patient-Controlled Analgesia and Single Antiemetic Prophylaxis
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Choi JB, Shim YH, Lee YW, Lee JS, Choi JR, Chang CH
- KMID: 1799513
- Yonsei Med J.
- 2014 Sep;55(5):1430-1435.
- doi: 10.3349/ymj.2014.55.5.1430
PURPOSE: We evaluated the incidence and risk factors of postoperative nausea and vomiting (PONV) in patients with fentanyl-based intravenous patient-controlled analgesia (IV-PCA) and single antiemetic prophylaxis of 5-hydroxytryptamine type 3... -
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