Tuberc Respir Dis.  2004 Dec;57(6):573-578. 10.4046/trd.2004.57.6.573.

A Case of Idiopathic Hypereosinophilic Syndrome Complicated with Pulmonary Thromboembolism and Disseminated Intravascular Coagulation

Affiliations
  • 1Department of Internal Medicine, and Thoracic Surgery Seoul Paik Hospital, Inje University, Korea. pulho@korea.com

Abstract

The idiopathic hypereosinophilic syndrome (HES) comprises a heterogeneous group of disorders with unknown pathogenesis characterized by persistent peripheral blood and bone marrow eosinophilia. And the eosinophil infiltrates of multiple organs in HES lead to severe organ dysfunction. The disseminated intravascular coagulation (DIC) is a rare complication of HES. We have experienced a case of HES complicated with DIC and pulmonary thromboembolism. After intravenous injection of methylprednisone, blood eosinophil count was normalized but DIC was persisted. With cortico steroid and cyclosporine therapy, the disease activity was favorably remitted.

Keyword

Idiopathic hypereosinophilic syndrome; DIC; cyclosporin; thromboembolism

MeSH Terms

Bone Marrow
Cyclosporine
Dacarbazine
Disseminated Intravascular Coagulation*
Eosinophilia
Eosinophils
Hypereosinophilic Syndrome*
Injections, Intravenous
Pulmonary Embolism*
Thromboembolism
Cyclosporine
Dacarbazine
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