- Development of an Automated Image Analyzer for Microvessel Density Measurement in Bone Marrow Biopsies
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Chung Y, Shin S, Shim H, Sohn JY, Lee DE, Lee H, Eom HS, Kim KG, Kong SY
- KMID: 2470327
- Ann Lab Med.
- 2020 Jul;40(4):312-316.
- doi: 10.3343/alm.2020.40.4.312
Angiogenesis is important for the proliferation and survival of multiple myeloma (MM) cells. Bone marrow (BM) microvessel density (MVD) is a useful marker of angiogenesis and an increase in MVD... -
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- Clinical, Laboratory, and Bone Marrow Findings of 31 Patients With Waldenström Macroglobulinemia
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Ahn A, Park CJ, Cho YU, Jang S, Seo EJ, Lee JH, Yoon DH, Suh C
- KMID: 2466011
- Ann Lab Med.
- 2020 May;40(3):193-200.
- doi: 10.3343/alm.2020.40.3.193
BACKGROUND: Waldenström macroglobulinemia (WM) is a subset of lymphoplasmacytic lymphoma (LPL) with bone marrow (BM) involvement and an IgM monoclonal gammopathy of any level. We aimed to identify the clinical,... -
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- Necrobiotic Xanthogranuloma Coexists with Diffuse Normolipidemic Plane Xanthoma and Multiple Myeloma
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Kim JG, Kim HR, You MH, Shin DH, Choi JS, Bae YK
- KMID: 2467201
- Ann Dermatol.
- 2020 Feb;32(1):53-56.
- doi: 10.5021/ad.2020.32.1.53
Necrobiotic xanthogranuloma (NXG), is a rare multisystem disease that manifests as cutaneous inflammatory lesions, and is commonly associated with lymphoproliferative disease. Diffuse normolipemic plane xanthoma (NX), is also a rare,... -
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- A Case of Donor Cell Leukemia after Allogenic Peripheral Blood Stem Cell Transplantation for Acute Promyelocytic Leukemia with PML-RARA
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Shin WY, Bang HI, Kim J, Kim KH, Won JH, Park R
- KMID: 2466771
- Lab Med Online.
- 2020 Jan;10(1):88-91.
- doi: 10.3343/lmo.2020.10.1.88
Donor cell leukemia (DCL), a rare but fatal complication arising from allogenic stem cell transplantation, is a complex disease associated with multiple pathophysiological processes. Specific diagnosis of DCL distinct from... -
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- Autophagy in neutrophils
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Shrestha S, Lee JM, Hong CW
- KMID: 2466564
- Korean J Physiol Pharmacol.
- 2020 Jan;24(1):1-10.
- doi: 10.4196/kjpp.2020.24.1.1
Autophagy is a highly conserved intracellular degradation and energy-recycling mechanism that contributes to the maintenance of cellular homeostasis. Extensive researches over the past decades have defined the role of autophagy... -
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- Therapeutic Angiogenesis with Somatic Stem Cell Transplantation
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Murohara T
- KMID: 2465659
- Korean Circ J.
- 2020 Jan;50(1):12-21.
- doi: 10.4070/kcj.2019.0288
Therapeutic angiogenesis is an important strategy to rescue ischemic tissues in patients with critical limb ischemia having no other treatment option such as endovascular angioplasty or bypass surgery. Studies indicated... -
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- JL1 Antigen Expression on Bone Marrow Lymphoma Cells from Patients With Non-Hodgkin Lymphoma
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Kim MS, Park CJ, Cho YU, Jang S, Seo EJ, Park CS, Huh J, Im HJ, Seo JJ, Yoon DH, Suh C
- KMID: 2457486
- Ann Lab Med.
- 2020 Jan;40(1):1-6.
- doi: 10.3343/alm.2020.40.1.1
BACKGROUND: JL1, a CD43 epitope and mucin family cell surface glycoprotein, is expressed on leukemic cells. An anti-JL1 antibody combined with a toxic substance can have targeted therapeutic effects against... -
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- Clinical Effects of Hypomethylating Agents in Patients with Newly Diagnosed Myelodysplastic Syndrome Who Received DNA-Damaging Chemotherapy for Metastatic Breast Cancer
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Baek DW, Lee SJ, Sohn SK, Moon JH, Chae YS
- KMID: 2470901
- J Breast Cancer.
- 2019 Dec;22(4):647-652.
- doi: 10.4048/jbc.2019.22.e50
The cumulative risk of therapy-related myelodysplastic syndrome (t-MDS) in breast cancer patients exposed to chemotherapy and/or radiotherapy is significantly high compared to that in other cancer patients. This report reviews... -
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- Management of a dental implant displaced into the mandibular bone marrow space: Case reports
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Choi EJ, Kim HJ, Moon SY
- KMID: 2470515
- Oral Biol Res.
- 2019 Dec;43(4):356-360.
- doi: 10.21851/obr.43.04.201912.356
When an implant fixture is displaced to the bone marrow defect site of the mandible, damage to the inferior alveolar nerve may occur. To minimize postoperative side effects, an accurate... -
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- Treatment Effect with Weekly Teriparatide in the Vertebral Compression Fractures in Patients with Severe Osteoporosis
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Hwang SH, Woo YK, Jeon HS, Suh SP, Kim JY, Kim JN
- KMID: 2469884
- J Korean Orthop Assoc.
- 2019 Dec;54(6):528-536.
- doi: 10.4055/jkoa.2019.54.6.528
PURPOSE: This study examined the effects of a weekly teriparatide on the change in vertebral compression ratio, back pain, and vertebral fracture healing in osteoporosis patients with vertebral compression fractured... -
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- Clinical Use of Mesenchymal Stem Cells in Bone Regeneration
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Park CW, Lim SJ, Park YS
- KMID: 2469880
- J Korean Orthop Assoc.
- 2019 Dec;54(6):490-497.
- doi: 10.4055/jkoa.2019.54.6.490
Owing to the recent advances in biological knowledge on stem cells, many efforts are being made to apply them to clinical practice. Although mesenchymal stem cells were first found in... -
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- Current Trends for Treating Lateral Epicondylitis
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Kim GM, Yoo SJ, Choi S, Park YG
- KMID: 2468836
- Clin Should Elbow.
- 2019 Dec;22(4):227-234.
- doi: 10.5397/cise.2019.22.4.227
Lateral epicondylitis, also known as ‘tennis elbow’, is a degenerative rather than inflammatory tendinopathy, causing chronic recalcitrant pain in elbow joints. Although most patients with lateral epicondylitis resolve spontaneously or... -
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- Potential biomarkers and antagonists for fluoranthene-induced cellular toxicity of bone marrow derived mesenchymal stem cells
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Hoque MM, Lee YE, Kim HR, Shin MG
- KMID: 2466590
- Blood Res.
- 2019 Dec;54(4):253-261.
- doi: 10.5045/br.2019.54.4.253
BACKGROUND: Fluoranthene (FR) is a common environmental pollutant that exists in a complex mixture with other polycyclic aromatic hydrocarbons (PAHs). We identified biomarkers for monitoring FR exposure and investigated the... -
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- Inactivation of the NHEJ Activity of DNA-PKcs Prevents Fanconi Anemia Pre-Leukemic HSC Expansion
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Chatla S, Wilson AF, Pang Q
- KMID: 2465886
- Int J Stem Cells.
- 2019 Nov;12(3):457-462.
- doi: 10.15283/ijsc19074
Fanconi anemia (FA) is a genetic disorder characterized by bone marrow failure and high risk of cancer particularly leukemia. Here we show that inactivation of the non-homologous end-joining (NHEJ) activity... -
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- Comparison of the Cardiomyogenic Potency of Human Amniotic Fluid and Bone Marrow Mesenchymal Stem Cells
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Jain M, Minocha E, Tripathy N, Singh N, Chaturvedi CP, Nityanand
- KMID: 2465885
- Int J Stem Cells.
- 2019 Nov;12(3):449-456.
- doi: 10.15283/ijsc18087
BACKGROUND AND OBJECTIVES: Most studies in cardiac regeneration have explored bone marrow mesenchymal stem cells (BM-MSC) with variable therapeutic effects. Amniotic fluid MSC (AF-MSC) having extended self-renewal and multi-potent properties... -
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- Perivascular Stem Cells Suppress Inflammasome Activation during Inflammatory Responses in Macrophages
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Kim J, Kim WJ, Ha KS, Han ET, Park WS, Yang SR, Hong SH
- KMID: 2465882
- Int J Stem Cells.
- 2019 Nov;12(3):419-429.
- doi: 10.15283/ijsc19115
BACKGROUND AND OBJECTIVES: Perivascular stem cells (PVCs) have been identified as precursors of mesenchymal stem cells (MSCs) that offer promising prospects for application in the development of cellular therapies. Although... -
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- The Effect of Mesenchymal Stem Cells Derived Microvesicles on the Treatment of Experimental CCL4 Induced Liver Fibrosis in Rats
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Sabry D, Mohamed A, Monir M, Ibrahim HA
- KMID: 2465880
- Int J Stem Cells.
- 2019 Nov;12(3):400-409.
- doi: 10.15283/ijsc18143
BACKGROUND AND OBJECTIVES: The release of microvesicles (MVs) from mesenchymal stem cells (MSCs) has been implicated in intercellular communication, and may contribute to beneficial paracrine effects of stem cell-based therapies.... -
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- Bone Marrow Foot Oedema in Adolescents: The Role of Vitamin D
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Pieropan S, Antoniazzi F, Tadiotto E, Caldonazzi F, Maschio M, Aiello G, Melotti G, Cavarzere , Piacentini G
- KMID: 2465025
- J Bone Metab.
- 2019 Nov;26(4):241-246.
- doi: 10.11005/jbm.2019.26.4.241
BACKGROUND: Bone marrow oedema (BMO) in children/adolescents is a rare clinical condition without an etiologic cause. It is associated with typical increased signal intensity on T2-weighted magnetic resonance images (MRI)... -
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- Prognostic Significance of the Imaging Parameters of Adipose Tissue and Bone Marrow on F-18 Fluorodeoxyglucose PET/CT in Patients with Malignant Melanoma
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Lee JH, Lee SM, Kim JE
- KMID: 2464912
- J Korean Soc Radiol.
- 2019 Nov;80(6):1132-1144.
- doi: 10.3348/jksr.2019.80.6.1132
PURPOSE: Fluorodeoxyglucose (FDG) uptake of bone marrow (BM) and adipose tissue is known to reflect systemic inflammatory response to cancer cell. The objective of this study was to evaluate the... -
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- POEMS Syndrome: Bone Marrow, Laboratory, and Clinical Findings in 24 Korean Patients
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Shim H, Seol CA, Park CJ, Cho YU, Seo EJ, Lee JH, Yoon DH, Suh CW, Park SH, Jang S
- KMID: 2450951
- Ann Lab Med.
- 2019 Nov;39(6):561-565.
- doi: 10.3343/alm.2019.39.6.561
POEMS syndrome is a rare paraneoplastic syndrome, which includes polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes due to plasma cell (PC) neoplasm. Diagnosis of this disease is challenging because of... -
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