Korean J Clin Pathol.
1998 Sep;18(3):396-398.
A Case of Wound Infection Caused by Staphylococcus aureus with Decreased Susceptibility to Teicoplanin
- Affiliations
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- 1Department of Clinical Pathology, Catholic University of Korea, College of Medicine, Seoul, Korea.
Abstract
- With increased infection by methicillin-resistant staphylococci, the use of glycopeptides has been increasing. Recently, staphylococci with decreased susceptibility to glycopeptides, especially teicoplanin, are increasingly reported. We isolated a Staphylococcus aureus strain isolated repeatedly from a wound culture, which showed susceptibility to teicoplanin by the disk diffusion method but showed growth on the Mueller-Hinton agar containing 6 g/mL of teicoplanin. This strain was clinically resistant to treatment at 200 mg/day of teicoplanin. By changing the treatment into combining rifampin (600 mg/day) and increasing the dose of teicoplanin (400 mg/day), the S. aureus was not isolated any more.
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