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Inhibition of the interaction between Hippo/YAP and Akt signaling with ursolic acid and 3′3-diindolylmethane suppresses esophageal cancer tumorigenesis

Meng RY, Li CS, Hu D, Kwon SG, Jin H, Chai OH, Lee JS, Kim SM

Hippo/YAP signaling hinders cancer progression. Inactivation of this pathway contributes to the development of esophageal cancer by activation of Akt. However, the possible interaction between Akt and Hippo/YAP pathways in esophageal...
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Radiographic evaluation before surgical extraction of impacted third molar to reduce the maxillary sinus related complication

Seo MH, Sodnom-Ish B, Eo MY, Myoung H, Kim SM

Objectives: Surgical extraction of maxillary third molars is routine in departments devoted to oral and maxillofacial surgery. Because maxillary third molars are anatomically adjacent to the maxillary sinus, complications such...
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Antineutrophil cytoplasmic antibody-associated vasculitis presenting as kidney rupture and gonadal artery hemorrhage

Lee HS, Choi MJ, Song IH, Kim SM

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Reasonable necessity of preoperative laboratory tests in office-based oral and maxillofacial surgery

Seo MH, Eo MY, Mustakim KR, Sodnom-Ish B, Myoung H, Kim SM

Objectives: As medical history before surgery is often based on patient reporting, there is the possibility that patients intentionally hide underlying diseases or that dentists cannot recognize abnormal health states....
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The predictive value of procalcitonin for septic shock in sepsis patients

Lim HB, Kwon HJ, Kim B, Kim SM, Hong Si, Chae B, Kim WY, Ryoo SM

  • KMID: 2543877
  • J Korean Soc Emerg Med.
  • 2023 Jun;34(3):249-255.
Objective: This study examined the difference in procalcitonin between sepsis and septic shock. Methods: The single-center retrospective cohort study was conducted from July 2017 to June 2018 at an emergency department...
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Clinical features and test indications of 11,087 patients undergoing cardiac magnetic resonance imaging during a decade in a tertiary referral center: A retrospective observational study

Jang SY, Kim J, Kim YS, Chang YA, Jung W, Kim HO, Yoo K, Kim EK, Chang SA, Park SJ, Park SW, Kim DK, Kim SM, Huh J, Song J, Kang IS, Cho SJ, Oh JK, Lee SC, Choe YH

Purpose: We evaluated the clinical characteristics of patients undergoing cardiac magnetic resonance (CMR) examinations over 10 years at a tertiary referral hospital. Methods: This retrospective study included 11,087 CMR examinations performed...
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Functional Magnetic Resonance Imaging and Diffusion Tensor Imaging for Language Mapping in Brain Tumor Surgery: Validation With Direct Cortical Stimulation and Cortico–Cortical Evoked Potential

Kang KM, Kim KM, Kim IS, Kim JH, Kang H, Ji SY, Dho YS, Oh H, Park HP, Seo HG, Kim SM, Choi SH, Park CK

Objective: Functional magnetic resonance imaging (fMRI) and diffusion tensor imaging-derived tractography (DTI-t) contribute to the localization of language areas, but their accuracy remains controversial. This study aimed to investigate the...
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A Case of Zosteriform Spiradenoma Following Varicose Veins

Yim SH, Kim SM, Park S, Hong D, Jung KE, Lee Y, Seo YJ

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Low-Density Lipoprotein Cholesterol Levels Are Associated With Subsequent Stented-Territory Ischemic Stroke After Carotid Artery Stenting: A Single Center Retrospective Study

Kim SM, Ryu JC, Koo S, Kim JS, Kim BJ

Objective: The role of low-density lipoprotein cholesterol (LDL-C) after carotid artery stenting (CAS) is not well known with respect to stented-territory infarction (STI) and instent restenosis (ISR). We hypothesized that...
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The introduction to air pollution on pregnancy outcome (APPO) study: a multicenter cohort study

Hur YM, Park S, Kwon E, You YA, Ansari A, Kim SM, Lee G, Park MH, Lee KA, Kim SJ, Kim YH, Jung Ys, Cho GJ, Oh MJ, Na SH, Lee Sj, An TG, Bae JG, Kim YH, Lee SJ, Kim NK, Ha EH, Kim YJ

Objective The air pollution on pregnancy outcome (APPO) study is a prospective hospital-based cohort study designed to investigate the maternal and fetal effects of a particulate matter with an aerodynamic...
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Efficient Generation of Dopaminergic Neurons from Mouse Ventral Midbrain Astrocytes

Han JY, Lee EH, Kim SM, Park CH

Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by tremors, bradykinesia, and rigidity. PD is caused by loss of dopaminergic (DA) neurons in the midbrain substantia nigra (SN) and...
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Clinical significance of drug cessation on medication-related

Mustakim KR, Eo MY, Lee JY, Seo MH, Kim SM

Objectives: Suspending bisphosphonates (BPs) to reduce the risk and severity of medication-related osteonecrosis of the jaw (MRONJ) remains controversial. In this study, we quantitatively evaluated the clinical significance of BP...
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One-Year Clinical Outcomes After Diagnosis According to Early Medication Adherence in First-Episode Schizophrenia: A Nationwide, Health Insurance Data-Based Retrospective Cohort Study

Choi W, Joo SW, Ahn S, Choi YJ, Kim SM, Lee J

Objectives: Early pharmacologic intervention is considered necessary for improving the prognosis in patients with first-episode schizophrenia (FES). However, few nationwide population-based studies have focused on early medication adherence. We investigated...
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Pitavastatin Induces Apoptosis of Cutaneous Squamous Cell Carcinoma Cells through Geranylgeranyl PyrophosphateDependent c-Jun N-Terminal Kinase Activation

Kim KI, Kim SM, Lee YY, Lee Y, Kim CD, Yoon TJ

Background: Pitavastatin is a cholesterol-lowering drug and is widely used clinically. In addition to this effect, pitavastatin has shown the potential to induce apoptosis in cutaneous squamous cell carcinoma (SCC)...
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Comprehensive Analysis of Epstein-Barr Virus LMP2A-Specific CD8+ and CD4+ T Cell Responses Restricted to Each HLA Class I and II Allotype Within an Individual

Jo HA, Hyun SJ, Hyun YS, Lee YH, Kim SM, Baek IC, Sohn HJ, Kim TG

Latent membrane protein 2A (LMP2A), a latent Ag commonly expressed in Epstein-Barr virus (EBV)-infected host cells, is a target for adoptive T cell therapy in EBV-associated malignancies. To define whether...
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Immune-enhancing effect of hydrolyzed and fermented Platycodon grandiflorum extract in cyclophosphamide-induced immunosuppressed BALB/c mice

Lee HS, Kim SM, Jung JI, Lim J, Woo M, Kim EJ

BACKGROUND/OBJECTIVES: The immunomodulatory effect of Platycodon grandiflorum (PG) has been reported, but studies on its mechanism are still lacking. This study was undertaken to confirm whether the hydrolyzed and fermented...
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Clinical Efficacy and Safety of Endoscopic Treatment of Gastrointestinal Stromal Tumors in the Stomach

Joo MK, Park JJ, Lee YH, Lee BJ, Kim SM, Kim WS, Yoo AY, Chun HJ, Lee SW

Background/Aims: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors in the stomach. We evaluated the clinical outcomes of endoscopic treatment for gastric GISTs. Methods: This is a single center,...
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Phytochemicals That Act on Synaptic Plasticity as Potential Prophylaxis against Stress-Induced Depressive Disorder

Yoon S, Iqbal H, Kim SM, Jin M

Depression is a neuropsychiatric disorder associated with persistent stress and disruption of neuronal function. Persistent stress causes neuronal atrophy, including loss of synapses and reduced size of the hippocampus and...
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Subjective Gustatory Dysfunction Is Correlated With Subjective Olfactory Dysfunction in Geriatric Patients Regardless of Cognitive Function

Min HJ, Kim SH, Park SY, Choi JH, Kim SM, Han DH, Kim KS

Background and Objectives Fewer studies are available on geriatric patients’ gustatory dysfunction than on their olfactory dysfunction. Here we aimed to evaluate the relationship between subjective gustatory dysfunction and subjective...
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Clinical features of anaphylaxis and risk factors of severe anaphylaxis in the emergency department

Kim SW, Jin YH, Jeong TO, Yoon JC, Kim SE, Oh TH, Kim SM, Lee JB

  • KMID: 2540092
  • J Korean Soc Emerg Med.
  • 2023 Feb;34(1):79-86.
Objective: This study investigates the triggers and clinical features of anaphylaxis, and determines the risk factors associated with severe anaphylaxis. Methods: This is a retrospective observational study spanning a duration of...
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