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Clinical Characteristics and Outcomes of Patients with Culture-Negative Pyogenic Spondylitis according to Empiric Glycopeptide Use

Lee YD, Jeon YH, Kim YH, Ha KY, Hur JW, Ryu KS, Kim JS, Kim YJ

BACKGROUND: The optimal choice of antibiotics is challenging in culture-negative pyogenic spondylitis (PS). The empiric use of glycopeptides is suggested depending on various risk factors, although clinical data are sparse....
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Pediatric adverse drug reactions collected by an electronic reporting system in a single tertiary university hospital

Park GM, Park JH, Jung JW, Han HW, Kim JY, Lee E, Cho HJ, Kim Y, Yoon J, Yu J, Kim TB, Hong SJ

PURPOSE: The incidence of adverse drug reactions (ADRs) is increasing. However, studies on the prevalence of ADRs in children are rare. The aim of this study was to investigate the...
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Clinical Usefulness of Arbekacin

Lee JH, Lee CS

Arbekacin is a broad-spectrum aminoglycoside used to treat methicillin-resistant Staphylococcus aureus (MRSA). Arbekacin has antibacterial activities against high-level gentamicin-resistant Enterococci, multidrug-resistant Pseudomonas aeruginosa, and Acinetobacter baumannii et al. Here, we...
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Annual Report on the External Quality Assessment Scheme for Clinical Microbiology in Korea (2015)

Chang J, Kim MN, Kim EC, Shin JH, Lee NY, Kim S, Jeong SH, Kim JS, Kim CK, Bae HG, Yoon NS, Joo SI, Song DJ, Kim K, Jeong TJ, Heo J, Clinical Microbiology Subcommittee, Korean Association of External Quality Assessment Service

Annual proficiency surveys were conducted in March, June, and September in 2015 by the Clinical Microbiology Subcommittee of the Korean Association of External Quality Assessment Service. The program covers the...
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A case of peritoneal dialysis-associated peritonitis by Rothia mucilaginosa

Kim BG, Cho AY, Kim SS, Lee SH, Shin HS, Yoon HJ, Kim JG, Sun IO, Lee KY

Rothia muciliaginosa (R. mucilaginosa) is a facultative, Gram-positive coccus that is considered to be part of the normal flora of the mouth and respiratory tract. There are sporadic reports of...
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Copeptin in Hemodialysis Patients with Left Ventricular Dysfunction

Kim JS, Yang JW, Chai MH, Lee JY, Park H, Kim Y, Choi SO, Han BG

PURPOSE: Copeptin has been considered as a useful marker for diagnosis and prediction of prognosis in heart diseases. However, copeptin has not been investigated sufficiently in hemodialysis patients. This study...
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Glycopeptide Antibiotics: Structure and Mechanisms of Action

Kang HK, Park Y

Glycopeptides of the clinically important antibiotic drugs are glycosylated cyclic or polycyclic nonribosomal peptides. Glycopeptides such as vancomycin and teicoplanin are often used for the treatment of gram-positive bacteria in...
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Risk Factors for Prolonged Carriage and Reacquisition of Vancomycin-resistant Enterococci

Lee D, Park ES, Yong D, Choi JY, Lee K, Jee SH

BACKGROUND: Patients infected with vancomycin-resistant enterococci (VRE) are kept in isolation to prevent the spread of VRE in medical facilities. However, decision-making regarding isolation can be challenging at the time...
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Oral Antimicrobial Therapy: Efficacy and Safety for Methicillin-Resistant Staphylococcus aureus Infections and Its Impact on the Length of Hospital Stay

Yoon YK, Kim ES, Hur J, Lee S, Kim SW, Cheong JW, Choo EJ, Kim HB

BACKGROUND: Carefully switching from intravenous to oral antibiotic therapy has shown to reduce treatment costs and lengths of hospital stay as well as increase safety and comfort in patients with...
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Adverse Drug Reactions of Long-term Intravenous Antibiotics in Patients with Pyogenic Spondylitis

Kim DH, Kim HS, Nam KH, Choi BK, Han IH

OBJECTIVE: The purpose of this study was to investigate the incidence, cause, and influence of the adverse drug reactions (ADRs) associated with long-term intravenous antibiotics in patients with pyogenic spondylitis...
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Clinical and Microbiologic Characteristics of Clostridium difficile Infection Caused by Binary Toxin Producing Strain in Korea

Kim J, Seo MR, Kang JO, Choi TY, Pai H

BACKGROUND: Binary toxin-producing Clostridium difficile infections (CDI) are known to be more severe and to cause higher case fatality rates than those by binary toxin-negative isolates. There has been few...
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Effect of Isolation Policy Using Cohorting Rooms on Isolation Rate of Multidrug-resistant Organisms and Antimicrobial Use Density: Focusing on Methicillin-Resistant Staphylococcus aureus and Multidrug-resistant Acinetobacter baumannii

Bak MH, Cho OH, Baek EH, Kim S, Bae IG

BACKGROUND: We evaluated the effectiveness of isolation measures using cohorting rooms and antimicrobial use in reducing the isolation rate of methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant Acinetobacter baumannii (MDR-AB). METHODS: Four...
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New antimicrobials on the horizon

Lee MS

  • KMID: 2305799
  • Korean J Med.
  • 2009 Jul;77(1):35-51.
Recently, infections caused by antibiotic-resistant bacteria continue to climb in the community and the hospital around the world. Our current antimicrobial agents are gradually becoming ineffective and a new pipeline...
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Bacteriologic Features Investigaed by Aspiration technique in Oral and Maxillofacial Infections

Cho HY, Kim IK, Baek MK, Chang KS, Park SH, Park JW, Cho JH

  • KMID: 2005389
  • J Korean Assoc Oral Maxillofac Surg.
  • 2008 Oct;34(5):562-570.
Most purulent maxillofacial infections are of odontogenic origin. Treatment of infection includes the surgical intervention, such as incision and drainage, and adjunctive treatment. The use of high-dose antibiotics is also...
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Prognosis Factors of Clostridium difficile Associated Diarrhea

Kim JH, Kim HJ, Ku NS, Kim YK, Choi JY, Shin SY, Park YS, Kim YA, Kim MS, Jeong SJ, Choi HK, Song YG, Lee K, Kim JM

  • KMID: 1523518
  • Infect Chemother.
  • 2007 Apr;39(2):71-77.
BACKGROUND: Clostridium difficile associated diarrhea (CDAD) has a wide range of clinical manifestations. The prognostic factors of CDAD are not fully understood. MATERIALS AND METHODS: A retrospective cohort study of...
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Clinical implications on vancomycin-resistant enterococci isolated f rom the sp ecimen of pediatric patients in a university hosp ital

Park YH, Kim KJ, Kim KH, Chun JK, Lee TJ, Kim DS, Park ES

PURPOSE: While cases of vancomycin-resistant enterococci (VRE) have increasingly been reported worldwide since it was first reported in the late 1980s, there have been few systemic studies on the pediatric...
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A Survey on Antimicrobial Prescriptions and Stewardship Programs in Korea

Bang JH, Song KH, Park WB, Kim SH, Cho JH, Kim HB, Kim NJ, Oh M, Choe KW

  • KMID: 2285060
  • Infect Chemother.
  • 2006 Dec;38(6):316-324.
BACKGROUND: Previous studies in Korea showed that unnecessary antibiotic use could not be neglected, especially in prophylactic use. Currently many hospitals employ diverse antibiotic stewardship programs, but there are few...
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Change of Antimicrobial Use Density According to Application of Computerized Management Program for Restriction of Antimicrobials Use in a University Hospital

Lee BY, Kim CS, Ryu SY, Kwon KY, Lim JG, Lim TJ, Min BW, Ryoo NH, Cha SD

PURPOSE: Appropriate use of antimicrobials is an essential factor to treat infectious diseases and prevent acquisition of antimicrobial resistant pathogens. This study was undertaken to search that application of computerized...
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A Clinical Study of Infective Endocarditis in Childhood

Choi EN, Kwon JH, Choi KM, Hwang HD, Sin KM, Choi JY, Sul JH, Kim DS

  • KMID: 1875807
  • Korean J Pediatr.
  • 2004 Aug;47(8):844-850.
PURPOSE: Advances in the treatment of congenital heart disease and a decline in the incidence of rheumatic fever has led to changes in the causative organisms and the clinical outcome...
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Effects of Basic Hospital Infection Control Methods on the Isolation Rate of Methicillin: Resistant Staphylococcus aureus

Heo E, Kim ES, Kim BN, Whang DH, Jeong JW, Lee BR, Yum HK, Shin BM, Jun BH

  • KMID: 1990774
  • Korean J Nosocomial Infect Control.
  • 2004 Jun;9(1):17-25.
BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) is highly prevalent in hospitals in Korea. The overall rate of MRSA in hospitals in Korea was estimated over 60%. Recently hospital infections caused by...
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