Korean J Gastrointest Endosc.  2001 Jan;22(1):45-49.

Antibiotics Associated Hemorrhagic Colitis: A report of two cases

• Kwun KA
• Ham JH
• Kim EJ
• Chung IK
• Kim HS
• Park SH
• Lee MH
• Kim SJ

Abstract

Antibiotics related colitis is a well recognized disease entity which in its severest form may result in pseudomembranous colitis, whereas in another form, acute hemorrhagic colitis without pseudomembrane, related to the use of penicillin-type antibiotics is rarely reported. The clinical features of hemorrhagic colitis associated with antibiotics was characterized that the bloody diarrhea, often with abdominal cramping pain begins 2~7 days after starting the antibiotics and rapidly recovered after its withdrawal. Pathogenesis of this disease is not entirely clear. It has been believed that right-sided hemorrhagic colitis is one of the main forms of colitis associated with antibiotics, especially ampicillin derivatives or cephalosporin, but recent reports presented left-sided colitis. We experienced 2 cases of hemorrhagic colitis developed on the left colon after the introduction of quinolone.

Keyword

Antibiotics; Hemorrhagic colitis; Quinolone

MeSH Terms

Ampicillin
Anti-Bacterial Agents*
Colic
Colitis*
Colon
Diarrhea
Enterocolitis, Pseudomembranous
Ampicillin
Anti-Bacterial Agents