J Korean Neurol Assoc.
2006 Dec;24(6):581-584.
Two Cases of Metronidazole-Induced Neurotoxicity Lacking of Clinico-Radiological Correlation
- Affiliations
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- 1Department of Neurology, University of Ulsan College of Medicine, Seoul, Korea. sjchung@amc.seoul.kr
Abstract
- Metronidazole is an antimicrobial agent widely used for the treatment of trichomoniasis, giardiasis, amebiasis, and anaerobic bacterial infections. It has been reported that metronidazole-induced neurotoxicity is associated with responsible lesions on brain MRI. We report 2 patients with metronidazole-induced neurotoxicity, who had no responsible lesions on brain MRI for their neurological deficits. The pathogenic mechanisms are discussed.
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