J Korean Rheum Assoc.  2005 Mar;12(1):52-56.

A Case of Parvovirus B19 Related Arthropathy Associated with Antinuclear Antibody, Anti-Ro/SSA and Anti-La/SSB

• Yoon HJ
• Lee SS
• Juhng HG

Abstract

Parvovirus B19 has been recently identified as the cause of various diseases such as erythema infectiosum, transient aplastic crisis in patients with chronic hemolytic anemias, hydrops fetalis, bone marrow suppression in immunocompromised hosts, and lastly acute and chronic arthropathy mimicking rheumatoid arthritis (RA) and occasionally, systemic lupus erythematosus (SLE). We describe a female patient who presented with fever, chills, polyarthralgia, serologic and PCR evidence of presence of Parvovirus B19, and expression of antinuclear antibody, anti- Ro/SSA and anti-La/SSB. There has been no clinical findings suggestive or diagnostic of any diffuse connective tissue diseases in this patient. Although there has been reports of Parvovirus B19 infection mimicking RA and SLE with manifestations of various autoimmune antibodies including rheumatoid factor, antinuclear antibody, anti-dsDNA, antilymphocyte antibody, and antiphospholipid antibody, there has not been any report of anti-Ro/SSA and anti-La/SSB expression in the setting of parvoviral arthropathy and this is the first case report.

Keyword

Parvovirus B19; Arthropathy

MeSH Terms

Anemia, Hemolytic
Antibodies
Antibodies, Antinuclear*
Antibodies, Antiphospholipid
Antilymphocyte Serum
Arthralgia
Arthritis, Rheumatoid
Bone Marrow
Chills
Connective Tissue Diseases
Erythema Infectiosum
Female
Fever
Humans
Hydrops Fetalis
Immunocompromised Host
Lupus Erythematosus, Systemic
Parvovirus*
Polymerase Chain Reaction
Rheumatoid Factor
Antibodies
Antibodies, Antinuclear
Antibodies, Antiphospholipid
Antilymphocyte Serum
Rheumatoid Factor