- Similar transplant outcomes between haploidentical and unrelated donors after reduced-intensity conditioning with busulfan, fludarabine, and anti-thymocyte globulin in patients with acute leukemia or myelodysplastic syndrome
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Choi M, Heo JY, Shin DY, Lee JY, Koh Y, Hong J, Kim I, Yoon SS, Lee JO, Bang SM
- KMID: 2472005
- Blood Res.
- 2020 Mar;55(1):27-34.
- doi: 10.5045/br.2020.55.1.27
BACKGROUND: Although T-cell-replete hematopoietic cell transplantation (HCT) from haploidentical donors (HIDs) using anti-thymocyte globulin (ATG) has shown promising outcomes, previous studies often adopted heterogenous graft sources and conditioning. METHODS: We retrospectively... -
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- Comparison of clinical outcomes of deceased donor kidney transplantations, with a focus on three induction therapies
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Jeong ES, Lee KW, Kim SJ, Yoo HJ, Kim KA, Park JB
- KMID: 2468162
- Korean J Transplant.
- 2019 Dec;33(4):118-127.
- doi: 10.4285/jkstn.2019.33.4.118
BACKGROUND: Graft survival rate of kidney transplantation recipients improves after induction therapy. However, there is no conclusive evidence on which regimen is superior for deceased donor kidney transplantation (DDKT). This... -
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- Differential impact of anti-thymocyte globulin dosing by disease risk index in alternative donor peripheral blood stem cell transplantation in patients with acute leukemia or myelodysplastic syndrome after reduced intensity conditioning
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Choi M, Shin DY, Lee JY, Kim I, Yoon SS, Bang SM
- KMID: 2466598
- Blood Res.
- 2019 Dec;54(4):290-295.
- doi: 10.5045/br.2019.54.4.290
No abstract available. -
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- Usefulness of valacyclovir prophylaxis for cytomegalovirus infection after anti-thymocyte globulin as rejection therapy
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Ko EJ, Yu JH, Yang CW, Chung BH
- KMID: 2441017
- Korean J Intern Med.
- 2019 Mar;34(2):375-382.
- doi: 10.3904/kjim.2017.040
BACKGROUND/AIMS: Anti-thymocyte globulin (ATG) treatment for acute T-cell mediated rejection (TCMR) can increase the risk of cytomegalovirus (CMV) infection. We aimed to evaluate the effect of valacyclovir prophylaxis against CMV... -
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- Proposal of a Selective Prophylaxis Strategy Based on Risk Factors to Prevent Early and Late Pneumocystis jirovecii Pneumonia after Renal Transplantation
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Lee H, Han A, Choi C, Ahn S, Min SI, Min SK, Lee H, Kim YS, Yang J, Ha J
- KMID: 2430589
- J Korean Soc Transplant.
- 2018 Dec;32(4):92-103.
- doi: 10.4285/jkstn.2018.32.4.92
BACKGROUND: Currently, trimethoprim-sulfamethoxazole is used for Pneumocystis jirovecii pneumonia (PJP) prophylaxis, but it is associated with frequent adverse effects. This study evaluated the efficacy and safety of the current protocol... -
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- Effects and Predictive Factors of Immunosuppressive Therapy Combined with Umbilical Cord Blood Infusion in Patients with Severe Aplastic Anemia
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Zhang X, Li Z, Geng W, Song B, Wan C
- KMID: 2412655
- Yonsei Med J.
- 2018 Jul;59(5):643-651.
- doi: 10.3349/ymj.2018.59.5.643
PURPOSE: To investigate the efficacy and safety of umbilical cord blood (UCB) infusion (UCBI) plus immunosuppressive therapy (IST) treatment in comparison to IST treatment, as well as predictive factors for... -
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- Allogeneic hematopoietic stem cell transplantation in congenital hemoglobinopathies with myeloablative conditioning and rabbit anti-thymocyte globulin
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Park BK, Kim HS, Kim S, Lee JW, Park YS, Jang PS, Chung NG, Jeong DC, Cho B
- KMID: 2451033
- Blood Res.
- 2018 Jun;53(2):145-151.
- doi: 10.5045/br.2018.53.2.145
BACKGROUND: Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative therapy for β-thalassemia major (TM) and sickle cell disease (SCD) in children. Graft-versus-host disease (GVHD) and treatment-related mortality (TRM) remain... -
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- Fatal Invasive Pulmonary Aspergillosis after Combined Induction with Rituximab and Antithymocyte Globulin for Kidney Transplantation in a Sensitized Recipient, and Early Rejection Therapy with Plasmapheresis and Low-dose Immunoglobulin
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Jeong DW, Lee SH, Moon JY, Kim YG, Lee YH, Kim K, Park H, Joo SH
- KMID: 2375681
- J Korean Soc Transplant.
- 2017 Mar;31(1):52-57.
- doi: 10.4285/jkstn.2017.31.1.52
A high degree of sensitization to human leukocyte antigen requires more intensive induction therapy; however, this increases vulnerability to opportunistic infections following kidney transplantation. Although recent studies have suggested that... -
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- Targeted busulfan and fludarabine-based conditioning for bone marrow transplantation in chronic granulomatous disease
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Ju HY, Kang HJ, Hong CR, Lee JW, Kim H, Song SH, Yu KS, Jang IJ, Park JD, Park KD, Shin HY, Kim JG, Ahn HS
- KMID: 2362256
- Korean J Pediatr.
- 2016 Nov;59(Suppl 1):S57-S59.
- doi: 10.3345/kjp.2016.59.11.S57
Chronic granulomatous disease (CGD) is a primary immunodeficiency disease caused by impaired phagocytic function. Hematopoietic stem cell transplantation (HSCT) is a definitive cure for CGD; however, the use of HSCT... -
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- Does anti-thymocyte globulin have a place in busulfan/fludarabine conditioning for matched related donor hematopoietic stem cell transplantation?
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Ji YS, Lee MS, Min CW, Park SK, Kim SH, Yun J, Kim HJ, Kim KH, Kim CK, Lee KT, Won JH, Hong DS
- KMID: 2327751
- Korean J Intern Med.
- 2016 Jul;31(4):750-761.
- doi: 10.3904/kjim.2015.234
BACKGROUND/AIMS: There is controversy about the prophylactic effect of anti-thymocyte globulin (ATG) on graft versus host disease (GVHD) in the setting of matched related-donor hematopoietic stem cell transplantation (HSCT). This... -
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- Successful Allogeneic Hematopoietic Stem Cell Transplantation for a Patient with Very Severe Aplastic Anemia During Active Invasive Fungal Infection
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Seo E, Kim H, Koh KN, Im HJ, Seo JJ
- KMID: 2168910
- Clin Pediatr Hematol Oncol.
- 2016 Apr;23(1):57-60.
- doi: 10.15264/cpho.2016.23.1.57
Allogeneic hematopoietic stem cell transplantation (HSCT) may not be considered feasible in a patient with active fungal infection due to transplant-related mortality. We report a case of HSCT performed on... -
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- Successful Treatment of Relapsed Acquired Amegakaryocytic Thrombocytopenia with Repeat Cyclosporine
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Bae SY, Han TH, Sohn BS, Oh HH, Choi SJ, Park M, Yuh YJ
- KMID: 2155943
- Korean J Med.
- 2016 Mar;90(3):258-261.
- doi: 10.3904/kjm.2016.90.3.258
Acquired amegakaryocytic thrombocytopenia (AAMT) is an unusual disease characterized by severe thrombocytopenia resulting from a marked decrease in bone marrow megakaryocytes. Various pathogenic mechanisms have been suggested, and several treatments... -
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- Graves disease following rabbit antithymocyte globulin treatment of severe aplastic anemia in a Korean child
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Choi IS, Kim HK, Han DK, Baek HJ, Jang HI, Kim CJ, Kook H
- KMID: 2140669
- Korean J Pediatr.
- 2015 Jul;58(7):267-269.
- doi: 10.3345/kjp.2015.58.7.267
Antithymocyte globulin (ATG) is used as an immunosuppressive treatment (IST) to deplete clonal suppressor T cells in patients with severe aplastic anemia (SAA). The depletion of suppressor T cells by... -
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- Comparison of the Clinical Outcomes between Anti-thymocyte Globulin and Basiliximab Induction Therapy in Deceased Donor Kidney Transplantation: Single Center Experience
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Cheon SU, Moon JI, Choi IS, Yoon SH, Hwang WM, Yun SR
- KMID: 2324353
- J Korean Soc Transplant.
- 2015 Jun;29(2):61-67.
- doi: 10.4285/jkstn.2015.29.2.61
BACKGROUND: The aim of this study is to evaluate the clinical outcomes between anti-thymocyte globulin (ATG) and basiliximab induction in deceased donor kidney transplantation (DDKT). METHODS: Between May 2006 and February... -
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- Treatment of Refractory Antibody-mediated Rejection with Bortezomib in a Kidney Transplant Recipient: A Case Report
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Lee JY, Yoo JY, Kwon SH, Jeon JS, Noh H, Han DC, Song D, Jin SY
- KMID: 2202536
- J Korean Soc Transplant.
- 2014 Jun;28(2):87-90.
- doi: 10.4285/jkstn.2014.28.2.87
Antibody-mediated rejection (ABMR) is associated with poor renal allograft survival. It shows poor response to conventional treatment with plasmapheresis, rituximab, and intravenous immunoglobulin. Bortezomib, a proteasome inhibitor used for treatment... -
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- A Case of Delayed Recovery from Antibody-Mediated Rejection
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Cho HJ, Shin EH, Yang YJ, Jung JW, Ji WJ, Choi YK, Park SK
- KMID: 2268501
- Korean J Med.
- 2014 Feb;86(2):237-241.
Antibody-mediated rejection (ABMR) in kidney transplant recipients is mediated by donor-specific antibodies. It is the major cause of graft failure in noncompliant patients and is associated with reduced long-term graft... -
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- Pneumatosis Intestinalis Developed due to CMV Infection in a Pediatric Severe Aplastic Anemia Patient after Hematopoietic Stem Cell Transplantation
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Seon MG, Jung HJ, Noh OK, Park JE
- KMID: 1807604
- Clin Pediatr Hematol Oncol.
- 2013 Oct;20(2):112-115.
A 10-year old girl diagnosed as severe aplastic anemia was transplanted with peripheral stem cells from a CMV seropositive full matched unrelated donor. The conditioning regimen consisted of busulfan, fludarabine,... -
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- Total lymphoid irradiation based conditioning for hematopoietic stem cell transplantation in severe aplastic anemia
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Lee YH, Kim JY, Choi BO, Ryu MR, Chung SM
- KMID: 2316715
- Radiat Oncol J.
- 2012 Dec;30(4):165-172.
PURPOSE: To retrospectively evaluate the outcome and toxicity of total lymphoid irradiation (TLI) based conditioning regimen for allogeneic hematopoietic stem cell transplantation (HSCT) in severe aplastic anemia (SAA) patients who... -
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- Factors influencing lymphocyte reconstitution after allogeneic hematopoietic stem cell transplantation in children
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Bae KW, Kim BE, Koh KN, Im HJ, Seo JJ
- KMID: 2251970
- Korean J Hematol.
- 2012 Mar;47(1):44-52.
- doi: 10.5045/kjh.2012.47.1.44
BACKGROUND: Immune reconstitution (IR) after hematopoietic stem cell transplantation (HSCT) reduces transplantation-related complications such as infection and improves HSCT outcomes. METHODS: We retrospectively analyzed IR of lymphocyte subpopulations in 38 pediatric... -
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- Allogeneic Hematopoietic Cell Transplantation from an HLA-mismatched Family Donor: The Current Status and Future
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Lee KH, Lee JH, Lee JH, Kim DY
- KMID: 2188060
- J Korean Med Assoc.
- 2009 Aug;52(8):819-830.
- doi: 10.5124/jkma.2009.52.8.819
Traditionally, human leukocyte antigen (HLA)-mismatched hematopoietic cell transplantation (HCT) has been considered ill-advised in a routine clinical practice due to excessive serious post-transplant complications, such as graft failure, graft-versus-host disease,... -
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