J Korean Med Sci.  2000 Apr;15(2):199-202. 10.3346/jkms.2000.15.2.199.

Clinical constellation of annular erythema associated with anti-Ro/La autoantibodies

• Lee CW

• KMID: 648124
• DOI: http://doi.org/10.3346/jkms.2000.15.2.199

Abstract

Annular erythema (AE) associated with anti-Ro (SSA) and/or La (SSB) autoantibody in patients with Sjogren syndrome (SS) or with SS/systemic lupus erythematosus overlap syndrome (SS/SLE), has recently been described in Orientals, and it may be a counterpart of annular skin lesion of the subacute cutaneous LE seen mostly in Caucasians. The author examined five Korean AE patients in respect to dinical diversity. In this small-sample study, subtle differences appeared between individual cases regarding the serologic features and the diagnoses of the disease. Among the five cases, four had circulating anti-Ro and anti-La antibodies, and one had only anti-La. Regarding the diagnosis, one was SS/SLE, two were primary SS, and the remaining two were only "AE associated with anti-Ro/La antibody". There seem to be a wide clinical spectrum in the disease expression of AE associated with anti-Ro/La autoantibody than previously thought.

Keyword

Annular Erythema; Anti-Ro/La Antibody; Antibodies, Antinuclear; Sjogren's Syndrome; Lupus Erythematosus, Systemic

MeSH Terms

Adolescence
Adult
Antibodies, Antinuclear/immunology*
Case Report
Erythema/immunology*
Erythema/etiology
Female
Human
Lupus Erythematosus, Systemic/immunology*
Lupus Erythematosus, Systemic/complications
Male
Sjogren's Syndrome/immunology*
Sjogren's Syndrome/complications