- The effects of ascorbic acid on free radical injury in cultured retinal pigment epithelial cells
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Woo KI, Lee J
- KMID: 1735133
- Korean J Ophthalmol.
- 1995 Jun;9(1):19-25.
- doi: 10.3341/kjo.1995.9.1.19
This study was conducted to investigate the effect of ascorbic acid on oxidative injury of cultured porcine retinal pigment epithelial (RPE) cells induced by t-butylhydroperoxide. The porcine RPE cells were... -
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- Effect of t-butylhydroperoxide on Na+/-dependent glutamate uptake in rabbit brain synaptosome
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Lee HJ, Kim YK
- KMID: 2071508
- Korean J Physiol Pharmacol.
- 1997 Aug;1(4):367-376.
The effect of an organic peroxide, t-butylhydroperoxide (t-BHP), on glutamate uptake was studied in synaptosomes prepared from cerebral cortex. t-BHP inhibited the Na+/-dependent glutamate uptake with no change in the Na+/-independent uptake. This... -
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- The mechanism of t-butylhydroperoxide-induced apoptosis in IMR-32 human neuroblastoma cells
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Kim JA, Lee YS, Huh K
- KMID: 1917066
- Korean J Physiol Pharmacol.
- 1999 Feb;3(1):19-28.
Apoptosis has been implicated in the pathophysiological mechanisms of various neurodegenerative diseases. In a variety of cell types, oxidative stress has been demonstrated to play an important role in the apoptotic cell death.... -
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- Effect of Dipyridamole on the Reactive Oxygen Species and Oxidative Stress in Trabecular Meshwork Cells
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Lee KW, Kim JW
- KMID: 2216772
- J Korean Ophthalmol Soc.
- 2013 Mar;54(3):496-501.
- doi: 10.3341/jkos.2013.54.3.496
PURPOSE: To investigate the effects of dipyridamole (DPD) on the production of reactive oxygen species (ROS) and oxidative stress in cultured human trabecular meshwork cells (HTMC). METHODS: Antioxidant activity of DPD... -
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- Role of phospholipase A2 in oxidant-induced alteration in phosphate transport in primary cultured rabbit renal proximal tubule cells
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Park KM, Ko SH, Woo JS, Jung JS, Lee SH, Kim YK
- KMID: 2071540
- Korean J Physiol Pharmacol.
- 1998 Oct;2(5):601-609.
The present study was undertaken to examine the role of phospholipase A2 (PLA2) in oxidant-induced inhibition of phosphate transport in primary cultured rabbit renal proximal tubule cells. Uptakes of phosphate and glucose were... -
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- The effects of hydromorphone on astrocytic responses in cerebral ischemia
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Lee CH, Park YC, Kim JH, Kim WY, Lee YS, Kim YH, Min TJ
- KMID: 2169064
- Anesth Pain Med.
- 2016 Jan;11(1):23-27.
- doi: 10.17085/apm.2016.11.1.23
BACKGROUND: Ischemic insult during operation could cause ischemic-reperfusion injuries in brain and memory impairments. Total intravenous anesthesia (TIVA) is preferred in brain surgery to promote the use of motor evoked... -
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- Antioxidant effects of serotonin and L-DOPA on oxidative damages of brain synaptosomes
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Ham SS, Kim DH, Lee SH, Kim YS, Lee CS
- KMID: 1554130
- Korean J Physiol Pharmacol.
- 1999 Apr;3(2):147-155.
Antioxidant effects of serotonin and L-DOPA on neuronal tissues were examined by studying the oxidative damages of brain synaptosomal components. The study further explored the mechanism by which they exert protective actions. Serotonin... -
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- Role of Ca2+ influx in the tert-butyl hydroperoxide-induced apoptosis of HepG2 human hepatoblastoma cellse
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Kim JA, Kang YS, Kim YO, Lee SH, Lee YS
- KMID: 1109296
- Exp Mol Med.
- 1998 Sep;30(3):137-144.
Oxidative stress appears to be implicated in the pathogenesis of various diseases including alcoholic liver injury. In this study we investigated the mechanism of apoptosis induced by tert-butyl hydroperoxide (TBHP) in HepG2... -
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- Contradictory Effects of Superoxide and Hydrogen Peroxide on KCa3.1 in Human Endothelial Cells
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Choi S, Na HY, Kim JA, Cho SE, Suh SH
- KMID: 1429296
- Korean J Physiol Pharmacol.
- 2013 Jun;17(3):181-187.
- doi: 10.4196/kjpp.2013.17.3.181
Reactive oxygen species (ROS) are generated in various cells, including vascular smooth muscle and endothelial cells, and regulate ion channel functions. KCa3.1 plays an important role in endothelial functions. However,... -
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- Black rice extract protected HepG2 cells from oxidative stress-induced cell death via ERK1/2 and Akt activation
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Yoon J, Ham H, Sung J, Kim Y, Choi Y, Lee JS, Jeong HS, Lee J, Kim D
- KMID: 2313719
- Nutr Res Pract.
- 2014 Apr;8(2):125-131.
BACKGROUND/OBJECTIVES: The objective of this study was to evaluate the protective effect of black rice extract (BRE) on tert-butyl hydroperoxide (TBHP)-induced oxidative injury in HepG2 cells. MATERIALS/METHODS: Methanolic extract from black... -
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- Schisandra Chinensis Baillon regulates the gene expression of phase II antioxidant/detoxifying enzymes in hepatic damage induced rats
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Jang HI, Do GM, Lee HM, Ok HM, Shin JH, Kwon O
- KMID: 2313739
- Nutr Res Pract.
- 2014 Jun;8(3):272-277.
BACKGROUND/OBJECTIVES: This study investigated the antioxidant activities and hepatoprotective effects of Schisandra chinensis Baillon extract (SCE) against tert-butyl hydroperoxide (t-BHP)-induced oxidative hepatic damage in rats. MATERIALS/METHODS: Sprague-Dawley (SD) rats were pretreated... -
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- Assessment of Hemorheological Deformability of Human Red Cells Exposed to tert-Butyl Hydroperoxide, Verapamil and Ascorbate by Ektacytometer
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Kim DH, Kim YK, Won DI, Shin S, Suh JS
- KMID: 1781563
- Korean J Lab Med.
- 2008 Oct;28(5):325-331.
- doi: 10.3343/kjlm.2008.28.5.325
BACKGROUND: Normal erythrocyte is deformable and this facilitates blood flow in the capillaries. Oxidative stress reduces the deformability of erythrocytes, and influences on blood flow in microcirculation. The objective of... -
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- Effect of Ca2+ channel blockers, external Ca2+ and phospholipase A2 inhibitors on t-butylhydroperoxide-induced lipid peroxidation and toxicity in rat liver slices
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Heo J, Kim GH, Lee KS, Go WU, Ju HJ, Park SK, Song CS, Song GA, Cho M, Yang US, Moon HK, Kim YK
- KMID: 1051573
- Korean J Intern Med.
- 1997 Jun;12(2):193-200.
OBJECTIVES: This study was undertaken to examine the effect of oxidant on lipid peroxidation and lethal cell injury in rat liver slices. METHODS: t-Butylhydroperoxide (t-BHP) was employed as a model... -
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- Desalinated underground seawater of Jeju Island (Korea) improves lipid metabolism in mice fed diets containing high fat and increases antioxidant potential in t-BHP treated HepG2 cells
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Noh JR, Gang GT, Kim YH, Yang KJ, Lee CH, Na OS, Kim GJ, Oh WK, Lee YD
- KMID: 2421533
- Nutr Res Pract.
- 2010 Feb;4(1):3-10.
This study was performed to investigate the effect of desalinated underground seawater (named as 'magma seawater', MSW) of Jeju Island in Korea on lipid metabolism and antioxidant activity. MSW was... -
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- Effects of t-butyl hydrogen peroxide on single SR calcium release channels
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Shin JH, Kim KH, Suh CK
- KMID: 711527
- Yonsei Med J.
- 1998 Feb;39(1):56-60.
- doi: 10.3349/ymj.1998.39.1.56
Using lipid bilayer reconstitution technique, we investigated the oxidation effect of t-butyl hydrogen peroxide (tBHP) on the single channel activity of the sarcoplasmic reticulum (SR) calcium release channels isolated from... -
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