- Association of Tardive Dyskinesia with Cognitive Deficit in Schizophrenia
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Jang TS, Oh BH, Cheon JS
- KMID: 2334596
- J Korean Soc Biol Psychiatry.
- 1999 Jul;6(1):89-95.
To understand a mechanism of underlying cognitive deficit in schizophrenia, the risk factors, cognitive function, blood dopamine concentrations and glutamate dehydrogenase activities of male schizophrenics with tardive dyskinesia(N=30) were compared... -
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- Electrophoretic variations of enzyme, GDH (NADP-dependent glutamate dehydrogenase)(EC. 1.4.1.4) in characterizing clones and isolates of Malaysian Plasmodium falciparum
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Ang HH, Chan KL, Mak JW
- KMID: 1715358
- Korean J Parasitol.
- 1996 Sep;34(3):211-213.
- doi: 10.3347/kjp.1996.34.3.211
: Malaysian, African and Thai Plasmodium falciparum isolates were cultured in vitro by the Trager and Jensen method (1976; 1977) and were later cloned by the limiting dilution method (Rosario,... -
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- Simultaneous Detection of Clostridioides difficile Glutamate Dehydrogenase and Toxin A/B: Comparison of the C. DIFF QUIK CHEK COMPLETE and RIDASCREEN Assays
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Yoo IY, Song DJ, Huh HJ, Lee NY
- KMID: 2425979
- Ann Lab Med.
- 2019 Mar;39(2):214-217.
- doi: 10.3343/alm.2019.39.2.214
Various commercial assays have recently been developed for detecting glutamate dehydrogenase (GDH) and/or toxin A/B to diagnose Clostridioides difficile infection (CDI). We compared the performance of two assays for the... -
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- A Case of Persistent Hyperinsulinemic Hypoglycemia Treated with Diazoxide
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Kim MS, Park EH, Kim SY, Lee DY
- KMID: 1520749
- J Korean Soc Pediatr Endocrinol.
- 2007 Dec;12(2):164-167.
Congenital hyperinsulinism (CHI), the most important cause of hyperglycemia in early infancy, is a heterogenous disease characterized by dysregulation of insulin secretion. Mutations in five proteins have been associated with... -
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- A Case of Hyperinsulinism/hyperammonemia Syndrome
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Sung JY, Hong SY, Shin CH, Yang SW
- KMID: 1838802
- J Korean Soc Pediatr Endocrinol.
- 2005 Dec;10(2):236-240.
The hyperinsulinism/hyperammonemia (HI/HA) syndrome is a form of congenital hyperinsulinism. The children with HI/HA syndrome present recurrent symptomatic hypoglycemia and asymptomatic, persistent hyperammonemia, caused by mutations of the GLUD1 encoding... -
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- The Protective Effect of Chlorpromazine on Flurothyl-Induced Seizure
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Kim DW
- KMID: 2007390
- J Korean Child Neurol Soc.
- 2003 Nov;11(2):234-237.
PURPOSE: Chlorpromazine(CPZ) is known to inhibit glutamate ehydrogenase(GDH). Reductive amination of alpha-ketoglutarate is catalyzed by GDH and forms glutamate, a major excitatory neurotransmitter. Thus, I hypothesized that CPZ might have... -
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- Evaluation of a Rapid Membrane Enzyme Immunoassay for the Simultaneous Detection of Glutamate Dehydrogenase and Toxin for the Diagnosis of Clostridium difficile Infection
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Kim H, Kim WH, Kim M, Jeong SH, Lee K
- KMID: 1791926
- Ann Lab Med.
- 2014 May;34(3):235-239.
- doi: 10.3343/alm.2014.34.3.235
We evaluated the new C. DIFF QUIK CHEK COMPLETE (CD COMPLETE; TechLab, USA), which is a rapid membrane enzyme immunoassay that uses a combination of glutamate dehydrogenase (GDH) antigen and... -
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- Regulation of glutamate level in rat brain through activation of glutamate dehydrogenase by Corydalis ternata
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Lee KH, Huh JW, Choi MM, Yoon SY, Yang SJ, Hong HN, Cho SW
- KMID: 1093472
- Exp Mol Med.
- 2005 Aug;37(4):371-377.
When treated with protopine and alkalized extracts of the tuber of Corydalis ternata for one year, significant decrease in glutamate level and increase in glutamate dehydrogenase (GDH) activity was observed... -
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- Glutamate dehydrogenase antigen detection in Plasmodium falciparum infections
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Dominiguez Nd, Rodriguez-Acosta A
- KMID: 1715343
- Korean J Parasitol.
- 1996 Dec;34(4):239-246.
- doi: 10.3347/kjp.1996.34.4.239
The usefulness of malaria diagnosis by Plasmodium falciparum-GDH (NADP+), obtained by affinity chromatography, is demonstrated in ELISA assays, testing IgG antibodies against GDH (NADP+) from patients with acute malaria, who... -
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- The Changes in the Expression of gamma-Aminobutyric Acid Related Enzymes in the Mouse Hippocampus Following Ketogenic Diet
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Noh HS, Kwon OY, Yun HJ, Kang SS, Cho GJ, Choi WS
- KMID: 2224461
- Korean J Anat.
- 2007 Sep;40(3):219-225.
The ketogenic diet (KD) has been used to treat intractable childhood epilepsy. However, its mechanism of action remains unknown. In the present study, we examined the effects of KD on... -
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- A Case of Hyperinsulinism/Hyperammonemia (HI/HA) Syndrome due to a Mutation in the Glutamate Dehydrogenase Gene (GLUD1)
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Jin HY, Choi JH, Kim GH, Ko JM, Yoo HW
- KMID: 2322014
- J Korean Soc Pediatr Endocrinol.
- 2009 Dec;14(2):168-173.
Hyperinsulinism/Hyperammonemia (HI/HA) syndrome is a form of congenital hyperinsulinism (CHI) caused by a mutation in the GLUD1 gene. It is characterized by hyperinsulinemic hypoglycemia accompanying hyperammonemia. A 6-month-old male infant... -
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- Comparison of Simultaneous Use of C. DIFF QUIK CHEK and VIDAS C. difficile Toxin A&B to detect C. difficile in Fecal Specimen
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Cho SY, Rheu JK, Kim MH, Lee HJ
- KMID: 1466831
- J Lab Med Qual Assur.
- 2009 Dec;31(2):281-285.
BACKGROUND: Clostridium difficile is the most common pathogen of antibiotic-associated diarrhea. Toxigenic strains produce toxin A and toxin B. The pathogenicity of C. difficile is due to the production of... -
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- Laboratory Diagnosis of Clostridium difficile Infection in Korea: The First National Survey
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Chung HS, Park JS, Shin BM
- KMID: 2431610
- Ann Lab Med.
- 2019 May;39(3):317-321.
- doi: 10.3343/alm.2019.39.3.317
In May 2015, we conducted a voluntary online survey on laboratory diagnostic assays for Clostridium difficile infection (CDI) across clinical microbiology laboratories in Korea. Responses were obtained from 66 laboratories,... -
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- Genotyping of Giardia duodenalis Isolates from Dogs in Guangdong, China Based on Multi-Locus Sequence
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Zheng G, Alsarakibi M, Liu Y, Hu W, Luo Q, Tan L, Li G
- KMID: 1792186
- Korean J Parasitol.
- 2014 Jun;52(3):299-304.
This study aimed to identify the assemblages (or subassemblages) of Giardia duodenalis by using normal or nested PCR based on 4 genetic loci: glutamate dehydrogenase (gdh), triose phosphate isomerase (tpi),... -
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- Multiplex-Touchdown PCR to Simultaneously Detect Cryptosporidium parvum, Giardia lamblia, and Cyclospora cayetanensis, the Major Causes of Traveler's Diarrhea
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Shin JH, Lee SE, Kim TS, Ma DW, Chai JY, Shin EH
- KMID: 2360527
- Korean J Parasitol.
- 2016 Oct;54(5):631-636.
- doi: 10.3347/kjp.2016.54.5.631
This study aimed to develop a multiplex-touchdown PCR method to simultaneously detect 3 species of protozoan parasites, i.e., Cryptosporidium parvum, Giardia lamblia, and Cyclospora cayetanensis, the major causes of traveler’s... -
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- Human glutamate dehydrogenase is immunologically distinct from other mammalian orthologues
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Jang SH, Kim AY, Bahn JH, Eum WS, Kim DW, Park J, Lee KS, Kang TC, Won MH, Kang JH, Kwon OS, Yoon HY, Lee EY, Cho SW, Choi SY
- KMID: 1109312
- Exp Mol Med.
- 2003 Aug;35(4):249-256.
Five monoclonal antibodies (mAbs) that recognize human glutamate dehydrogenase (GDH) have been selected and designated as monoclonal antibodies hGDH60-6, hGDH60-8, hGDH63-10, hGDH63-11, and hGDH91-14. A total of five mAbs recognizing... -
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- Development of Molecular Diagnosis Using Multiplex Real-Time PCR and T4 Phage Internal Control to Simultaneously Detect Cryptosporidium parvum, Giardia lamblia, and Cyclospora cayetanensis from Human Stool Samples
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Shin JH, Lee SE, Kim TS, Ma DW, Cho SH, Chai JY, Shin EH
- KMID: 2426746
- Korean J Parasitol.
- 2018 Oct;56(5):419-427.
- doi: 10.3347/kjp.2018.56.5.419
This study aimed to develop a new multiplex real-time PCR detection method for 3 species of waterborne protozoan parasites (Cryptosporidium parvum, Giardia lamblia, and Cyclospora cayetanensis) identified as major causes... -
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