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The Risk of Gastrointestinal Cancer on Daily Intake of Low-Dose BaP in C57BL/6 for 60 Days

Zheng Z, Park JK, Kwon OW, Ahn SH, Kwon YJ, Jiang L, Zhu S, Park BH

Background: Benzo(a)pyrene (BaP) is a carcinogenic compound in contaminated foodstuffs. The effect of oral intake of the environmental carcinogen BaP under low doses and frequent exposure on a digestive system has...
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Fascia Suture Technique Is a Simple Approach to Reduce Postmastectomy Seroma Formation

Cong Y, Cao J, Qiao G, Zhang S, Liu X, Fang X, Zou H, Zhu S

Purpose: Seroma formation is a common complication in breast cancer patients undergoing mastectomy, and it negatively affects patient recovery after surgery. The present study aimed to evaluate a simple method...
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Disease Prevention Knowledge, Anxiety, and Professional Identity during COVID-19 Pandemic in Nursing Students in Zhengzhou, China

Sun Y, Wang D, Han Z, Gao J, Zhu S, Zhang H

Purpose: This study aimed to evaluate nursing students’ understanding of the prevention of COVID-19, as well as their anxiety towards the disease and their perception of their professional identity in...
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Comparison of the Distribution Pattern of 21-Gene Recurrence Score between Mucinous Breast Cancer and Infiltrating Ductal Carcinoma in Chinese Population: A Retrospective Single-Center Study

Wu J, Ding S, Lin L, Fei X, Lin C, Andriani L, Goh C, Huang J, Hong J, Gao W, Zhu S, Wang H, Huang O, Chen X, He J, Li Y, Shen K, Chen W, Zhu L

Purpose This retrospective study aimed to evaluate the distribution pattern and prognostic value of 21-gene recurrence score (RS) in Chinese patients with mucinous breast cancer (MC) and compared with infiltrating ductal...
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Selection and optimization of nutritional risk screening tools for esophageal cancer patients in China

Dong W, Liu X, Zhu S, Lu D, Cai K, Cai R, Li Q, Zeng J, Li M

BACKGROUND/OBJECTIVES: Malnutrition has multiple impacts on surgical success, postoperative complications, duration of hospital stay, and costs, particularly for cancer patients. There are various nutrition risk screening tools available for clinical...
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Dietary inflammatory index and risk of gynecological cancers: a systematic review and meta-analysis of observational studies

Liu ZY, Gao XP, Zhu S, Liu YH, Wang LJ, Jing CX, Zeng FF

OBJECTIVE: There has been growing body of literatures showing that chronic inflammation might play an important role in cancer development. This meta-analysis aimed to assess the association between the dietary...
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KLK6 Promotes Growth, Migration, and Invasion of Gastric Cancer Cells

Zhu S, Shi J, Zhang S, Li Z

PURPOSE: Kallikrein (KLK) proteases are hormone-like signaling molecules with critical functions in different cancers. This study investigated the expression of KLK6 in gastric cancer and its potential role in the...
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MicroRNA-200a Targets Cannabinoid Receptor 1 and Serotonin Transporter to Increase Visceral Hyperalgesia in Diarrhea-predominant Irritable Bowel Syndrome Rats

Hou Q, Huang Y, Zhang C, Zhu S, Li P, Chen X, Hou Z, Liu F

  • KMID: 2422855
  • J Neurogastroenterol Motil.
  • 2018 Oct;24(4):656-668.
  • doi: 10.5056/jnm18037
BACKGROUND/AIMS: MicroRNAs (miRNAs) were reported to be responsible for intestinal permeability in diarrhea-predominant irritable bowel syndrome (IBS-D) rats in our previous study. However, whether and how miRNAs regulate visceral hypersensitivity...
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Potential Vaccine Targets against Rabbit Coccidiosis by Immunoproteomic Analysis

Song H, Dong R, Qiu B, Jing J, Zhu S, Liu C, Jiang Y, Wu L, Wang S, Miao J, Shao Y

The aim of this study was to identify antigens for a vaccine or drug target to control rabbit coccidiosis. A combination of 2-dimensional electrophoresis, immunoblotting, and mass spectrometric analysis were...
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Korean pine nut oil replacement decreases intestinal lipid uptake while improves hepatic lipid metabolism in mice

Zhu S, Park S, Lim Y, Shin S, Han SN

BACKGROUND/OBJECTIVES: Consumption of pine nut oil (PNO) was shown to reduce weight gain and attenuate hepatic steatosis in mice fed a high-fat diet (HFD). The aim of this study was...
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miR-30c regulates proliferation, apoptosis and differentiation via the Shh signaling pathway in P19 cells

Liu X, Li M, Peng Y, Hu X, Xu J, Zhu S, Yu Z, Han S

MicroRNAs (miRNAs) are small, non-coding single-stranded RNAs that suppress protein expression by binding to the 3′ untranslated regions of their target genes. Many studies have shown that miRNAs have important...
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Elevated level of renal xanthine oxidase mRNA transcription after nephropathogenic infectious bronchitis virus infection in growing layers

Lin H, Huang Q, Guo X, Liu P, Liu W, Zou Y, Zhu S, Deng G, Kuang J, Zhang C, Cao H, Hu G

To assess relationships between xanthine oxidase (XOD) and nephropathogenic infectious bronchitis virus (NIBV) infection, 240 growing layers (35 days old) were randomly divided into two groups (infected and control) of...
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Fluoxetine Protects against Big Endothelin-1 Induced Anti-Apoptosis by Rescuing Kv1.5 Channels in Human Pulmonary Arterial Smooth Muscle Cells

Dai F, Mao Z, Xia J, Zhu S, Wu Z

PURPOSE: Pulmonary Kv channels are thought to play a crucial role in the regulation of cell proliferation and apoptosis. Previous studies have shown that fluoxetine upregulated the expression of Kv1.5...
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