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Belt & road organ donation capacity improvement cooperation training project (BROAOD)

Balleste C, Manyalich M, Kondi E, Zhao H, Pu M, Zhao J, Zhao Y, Wu Y

Background: China shows a continuous improvement in the practice of organ donation (OD) and transplantation (OT); reaching 4.16 pmp in 2019. China Organ Transplantation Development Foundation (COTDF) in cooperation with...
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Copper Deficiency Myeloneuropathy in a Patient With Wilson’s Disease

Wang Y, Wei Z, Mei J, Han X, Zhao H, Zhu Y, Jin P, Zhang Y

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Preparation, characterization, and in vivo evaluation of a polymorphic form of valnemulin hydrogen tartrate

Zhu X, Xu S, Lu L, Wang S, Zhao Q, Li D, Li J, Zhao H, Xu B

We prepared a polymorphic form of valnemulin hydrogen tartrate (Form I) to overcome the instability and irritating odor of valnemulin hydrochloride that affect its use in the production and application...
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Circular RNA hsa_circ_0005556 Accelerates Gastric Cancer Progression by Sponging miR-4270 to Increase MMP19 Expression

Shen D, Zhao H, Zeng P, Song J, Yang Y, Gu X, Ji Q, Zhao W

Purpose: Circular RNAs (circRNAs) are a new class of RNA molecules whose function is largely unknown. There is a growing evidence that circRNAs play an important regulatory role in the...
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Intravenous Tenecteplase for Acute Ischemic Stroke Within 4.5–24 Hours of Onset (ROSE-TNK): A Phase 2, Randomized, Multicenter Study

Wang L, Dai YJ, Cui Y, Zhang H, Jiang CH, Duan YJ, Zhao Y, Feng YF, Geng SM, Zhang ZH, Lu J, Zhang P, Zhao LW, Zhao H, Ma YT, Song CG, Zhang Y, Chen HS

Background and Purpose Intravenous tenecteplase (TNK) efficacy has not been well demonstrated in acute ischemic stroke (AIS) beyond 4.5 hours after onset. This study aimed to determine the effect of...
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Enhancement of Gastric Ulcer Healing and Angiogenesis by Hepatocyte Growth Factor Gene Mediated by Attenuated Salmonella in Rats

Ha X, Peng J, Zhao H, Deng Z, Dong J, Fan H, Zhao Y, Li B, Feng Q, Yang Z

The present study developed an oral hepatocyte growth factor (HGF) gene therapy strategy for gastric ulcers treatment. An attenuated Salmonella typhimurium that stably expressed high HGF (named as TPH) was...
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Validation of Reference Genes for Quantitative Real-Time PCR in Bovine PBMCs Transformed and Non-transformed by Theileria annulata

Zhao H, Liu J, Li Y, Yang C, Zhao S, Liu J, Liu A, Liu G, Yin H, Guan G, Luo J

Theileria annulata is a tick-borne intracellular protozoan parasite that causes tropical theileriosis, a fatal bovine lymphoproliferative disease. The parasite predominantly invades bovine B lymphocytes and macrophages and induces host cell...
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Effects of Antioxidant Tempol on Systematic Inflammation and Endothelial Apoptosis in Emphysematous Rats Exposed to Intermittent Hypoxia

Zhao H, Zhao Y, Li X, Xu L, Jiang F, Hou W, Dong L, Cao J

PURPOSE: Obstructive sleep apnea and chronic obstructive pulmonary disease are independent risk factors of cardiovascular disease (CVD), and their coexistence is known as overlap syndrome (OS). Endothelial dysfunction is the...
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Dimethyloxaloylglycine promotes spermatogenesis activity of spermatogonial stem cells in Bama minipigs

Cao Y, Dai Z, Lao H, Zhao H

Background: The testis has been reported to be a naturally O 2 -deprived organ, dimethyloxaloylglycine (DMOG) can inhibit hypoxia inducible factor-1alpha (HIF-1α) subject to degradation under normal oxygen condition in...
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Two New Species in the Family Cunninghamellaceae from China

Zhao H, Zhu J, Zong TK, Liu XL, Ren LY, Lin Q, Qiao M, Nie Y, Zhang ZD, Liu XY

The species within the family Cunninghamellaceae are widely distributed and produce important metabolites. Morphological studies along with a molecular phylogeny based on the internal transcribed spacer (ITS) and large subunit...
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Nephroprotective effect of astaxanthin against trivalent inorganic arsenic-induced renal injury in wistar rats

Wang X, Zhao H, Shao Y, Wang P, Wei Y, Zhang W, Jiang J, Chen Y, Zhang Z

  • KMID: 2313710
  • Nutr Res Pract.
  • 2014 Feb;8(1):46-53.
Inorganic arsenic (iAs) is a toxic metalloid found ubiquitously in the environment. In humans, exposure to iAs can result in toxicity and cause toxicological manifestations. Arsenic trioxide (As2O3) has been...
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Potential application of herbal medicine treatment based on pattern identification for canine cognitive dysfunctional syndrome: a comparative analysis of Korea medicine therapy for patients with dementia

Jung K, Zhao H, Choi Y, Jang JH

Canine cognitive dysfunction syndrome (CDS) is a neurodegenerative disease that causes cognitive and behavioral disorders and reduces the quality of life in dogs and their guardians. This study reviewed the...
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Efficacy and Safety of Gabapentin in the Treatment of Chronic Cough: A Systematic Review

Shi G, Shen Q, Zhang C, Ma J, Mohammed A, Zhao H

Despite recent clinical guidelines, the optimal therapeutic strategy for the management of refractory chronic cough is still a challenge. The present systematic review was designed to assess the evidence for...
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SERPINE1 as an Independent Prognostic Marker and Therapeutic Target for Nicotine-Related Oral Carcinoma

Guo X, Sun Z, Chen H, Ling J, Zhao H, Chang A, Zhuo X

Objectives. Nicotine is an ingredient of tobacco, and exposure to nicotine increases the risks of various cancers, including oral cancer. Previous studies have focused on the addictive properties of nicotine,...
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Adverse Events Associated With Synthetic Male Slings: An Analysis of the Food and Drug Administration Manufacturer and User Facility Device Experience Database

Zhao H, Souders CP, Kuhlmann PK, Dallas K, Eilber K, Anger JT

Purpose: We sought to describe and analyze the adverse events associated with synthetic male slings reported to the U.S. Food and Drug Administration (FDA) Manufacturer and User Facility Device Experience...
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The levels of liver enzymes and atypical lymphocytes are higher in youth patients with infectious mononucleosis than in preschool children

Wang Y, Li J, Ren YY, Zhao H

BACKGROUND/AIMS: Infectious mononucleosis (IM) is the clinical presentation of primary infection with Epstein-Barr virus. Although the literature contains a massive amount of information on IM, most of this is related...
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Protective efficacy of a novel multivalent vaccine in the prevention of diarrhea induced by enterotoxigenic Escherichia coli in a murine model

Zhao H, Xu Y, Li G, Liu X, Li X, Wang L

Background: Enterotoxigenic Escherichia coli (ETEC) infection is a primary cause of livestock diarrhea. Therefore, effective vaccines are needed to reduce the incidence of ETEC infection. Objectives: Our study aimed to develop...
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An Integrated Nomogram Combining Clinical Factors andMicrotubule-Associated Protein 1 Light Chain 3B Expression to PredictPostoperative Prognosis in Patients with Intrahepatic Cholangiocarcinoma

Chen L, Fu H, Lu T, Cai J, Liu W, Yao J, Liang J, Zhao H, Zhang J, Zheng J, Zhang Y, Yang Y

Purpose Microtubule-associated protein 1 light chain 3B (LC3B) serves as a key component of autophagy, which is associated with the progression of carcinoma. Yet, it is still unclear whether LC3B is also an...
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Clinical and Genetic Features of Brainstem Glioma in Adults: A Report of 50 Cases in a Single Center

Zhou C, Zhao H, Yang F, Huangfu L, Dong C, Wang S, Zhang J

Background and Purpose Brainstem gliomas (BSGs) in adults are rare brain tumors with dismal outcomes. The aim of this study was to determine the clinical and genetic features in a...
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Cadmium induces apoptosis in primary rat osteoblasts through caspase and mitogen-activated protein kinase pathways

Zhao H, Liu W, Wang Y, Dai N, Gu J, Yuan Y, Liu X, Bian J, Liu ZP

Exposure to cadmium (Cd) induces apoptosis in osteoblasts (OBs); however, little information is available regarding the specific mechanisms of Cd-induced primary rat OB apoptosis. In this study, Cd reduced cell...
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